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The Dow Jones Industrial Average had its largest single-day drop in the market's history on Thursday.The Dow finished the day down nearly 1,193 points. The previous largest one-day drop for the Dow was on Feb. 5, 2018, when the index lost 1,175 points.The Dow has lost more than 3,500 points since Friday, marking one of the worst weeks for the market in the last calendar year. Three of the five largest single-day drops in Dow Jones history took place this week.Stocks have been falling amid fears of a worldwide slowdown due to the spread of COVID-19, better known as the coronavirus. Though 607

The 2019 Nobel Prize for Medicine has been jointly awarded to William Kaelin Jr., Sir Peter Ratcliffe and Gregg Semenza for their pioneering research into how human cells respond to changing oxygen levels.Announcing the prize at the Karolinska Institute in Stockholm on Monday, the Nobel committee said that the trio's discoveries have paved the way for "promising new strategies to fight anaemia, cancer and many other diseases."The 2019 medicine laureates, the committee added, have identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen.The importance of oxygen has long been established, the committee explained, but how cells adapt to changes in its levels remained unknown.Randall Johnson, prize committee member, described the trio's work as a "textbook discovery.""This is something basic biology students will be learning about when they study, at aged 12 or 13, or younger, biology and learn the fundamental ways cells work. This is a basic aspect of how a cell works and, from that standpoint alone, it's a very exciting thing."The winnersNew York-born Kaelin established his own research laboratory at the Dana-Farber Cancer Institute in Boston and became a full professor at Harvard Medical School in 2002.Semenza, also born in New York, became a full-time professor at Johns Hopkins University in 1999 and since 2003 has been the Director of the Vascular Research Program at the Johns Hopkins Institute for Cell Engineering.Ratcliffe, who was born in Lancashire, England, studied medicine at Cambridge University and established an independent research group at Oxford University, becoming a full professor in 1996. 1694

The 2019 Scripps National Spelling Bee is here and Google shared America's top spelling searches — and the results are un-bee-lievable. For one, Hawaii can't spell "Hawaii." Secondly, a lot of people apparently struggle with "beautiful" and "grey."Here's each state's top spelling search.Alabama: Niece Alaska: Preferred Arizona: Patient Arkansas: Family California: Beautiful Colorado: Favorite Connecticut: Neighbor Delaware: Veterinarian Washington, D.C.: Enough Florida: Beautiful Georgia: Beautiful Hawaii: Hawaii Idaho: EmbarrassedIllinois: Beautiful Indiana: Activities Iowa: Loose Kansas: Committee Kentucky: Ninety Louisiana: Indict Maine: Guess Maryland: Heart Massachusetts: Grey Michigan: Amazing Minnesota: Especially Mississippi: Fifteen Missouri: Definitely Montana: Comma Nebraska: Delicious Nevada: Appreciate New Hampshire: Recess New Jersey: Grey New Mexico: Patience New York: Bougie North Carolina: Beautiful North Dakota: Independence Ohio: Favorite Oklahoma: February Oregon Phenomenal Pennsylvania: Pneumonia Rhode Island: Message South Carolina: Beautiful South Dakota: Jewelry Tennessee: Intelligent Texas: Beautiful Utah: Important Vermont: BenefitVirginia: Beautiful Washington: Grey West Virginia: Eleven Wyoming: Tear Wisconsin: OpinionSee the full map below. 1301

The nominations for the 71st Primetime Emmy Awards were announced Tuesday.Outstanding lead actor in a limited series or TV movieMahershala Ali, "True Detective"Benicio del Toro, "Escape at Dannemora"Hugh Grant, "A Very English Scandal"Jared Harris, "Chernobyl"Jharrel Jerome, "When They See Us"Sam Rockwell, "Fosse/Verdon"Outstanding lead actress in a limited series or TV movieAmy Adams, "Sharp Objects"Patricia Arquette, "Escape at Dannemora"Aunjanue Ellis, "When They See Us"Joey King, "The Act"Niecy Nash, "When They See Us"Michelle Williams, "Fosse/Verdon"Outstanding lead actor in a comedy seriesAnthony Anderson, "Black-ish"Don Cheadle, "Black Monday,"Ted Danson, "The Good Place"Michael Douglas, "The Kominksy Method"Bill Hader, "Barry"Eugene Levy, "Schitt's Creek"Outstanding lead actress in a comedy seriesChristina Applegate, "Dead to Me"Rachel Brosnahan, "The Marvelous Mrs. Maisel"Julia-Louis Dreyfus, "Veep"Natasha Lyonne, "Russian Doll"Catherine O'Hara, "Schitt's Creek"Phoebe Waller-Bridge, "Fleabag"Outstanding lead actor in a drama seriesJason Bateman, "Ozark"Sterling K. Brown, "This is Us"Kit Harrington, "Game of Thrones"Bob Odenkirk, "Better Call Saul"Billy Porter, "Pose"Milo Ventimiglia, "This Is Us"Outstanding lead actress in a drama seriesEmilia Clarke, "Game of Thrones"Jodie Comer, "Killing Eve"Viola Davis, "How to Get Away With Murder"Laura Linney, "Ozark"Mandy Moore, "This Is Us"Sandra Oh, "Killing Eve"Robin Wright, "House of Cards"Outstanding reality/competition series"The Amazing Race""American Ninja Warrior""Nailed It""RuPaul's Drag Race""Top Chef""The Voice"Outstanding variety talk series"The Daily Show with Trevor Noah""Full Frontal with Samantha Bee""Jimmy Kimmel Live""Last Week Tonight with John Oliver""The Late Late Show with James Corden""The Late Show with Stephen Colbert"Outstanding limited Series"Chernobyl""Escape at Dannemora""Fosse/Verdon"'Sharp Objects""When They See Us"Outstanding comedy series"Veep""The Marvelous Mrs. Maisel""Barry""The Good Place""Fleabag""Russian Doll""Schitt's Creek"Outstanding drama series"Better Call Saul""Bodyguard""Game of Thrones""Killing Eve""Ozark""Pose""Succession""This Is Us"Read below for a list of nominees in major categories and you can see more 2255

TEHRAN, Iran (AP) — Iran's government says 12 people have died nationwide from COVID-19, commonly known as coronavirus, and it has rejected claims of a much higher death toll by a lawmaker from the city of Qom that has been at the epicenter of the virus in the country. The conflicting reports raised questions about the Iranian government’s transparency concerning the scale of the outbreak. Iran's Health Ministry said total infections have risen to 61 while deaths stood at 12. However, a lawmaker from Qom was quoted by a semi-official news agency as saying the death toll was 50. Even with the lower toll of 12, the number of deaths compared to the number of confirmed infections is higher in Iran than in any other country.The 745