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SORRENTO VALLEY, Calif. (KGTV) - Another San Diego-based company is moving forward on developing a vaccine for the coronavirus. Sorrento Therapeutics is working on several projects that they believe could lead to viable vaccines or treatments. One of them was announced on Monday. Sorrento Therapeutics said it was partnering with Boston-based Smartpharm to create a gene-encoded antibody vaccine. “In the effort to more quickly resolve the global COVID-19 crisis, our company has initiated a rapidly accelerated program for the identification of potent neutralizing antibodies against SARS-CoV-2 coronavirus antigens that may be used for either treatment or prophylaxis,” said Henry Ji, CEO of Sorrento Therapeutics. Sorrento Therapeutics is also working on another vaccine called the I-Cell project. That vaccine uses a decoy virus to activate a person’s immune system to train it to attack the real virus. It’s also developing a protein called COVIDTRAP that can bind to the receptors on the coronavirus, thus blocking it from being able to bind to the receptors on healthy human cells. If proven succesful, it could be used as a treatment or preventative measure.How long will it take for them to be ready?“That all depends on what leeway the FDA gives us,” said Mark Brunswick, Senior Vice President of Regulatory Affairs at Sorrento Therapeutics. If they can get fast tracked, he estimates they can start clinical trials in 2 months, as opposed to 9-12 months normally. 1483

Severe storms in the South and Central US claimed four lives Saturday.Three people in Kentucky died in storms that included at least one tornado, and one death was reported in Arkansas.A 79-year-old woman died when she was hit by debris in her southwestern Kentucky home, the Logan County Sheriff's Office said. A tornado that passed through the area was likely EF-2 in strength, the National Weather Service said. That means winds may have gusted up to 110 mph.The county's emergency management office said some structures, including barns and grain bins, were damaged.A man was found dead in Simpson County, Kentucky, after his car became submerged in a creek, CNN affiliate WSMV reported.In Robertson County, on the other side of the border with Tennessee, there were also reports of overturned vehicles, windows blown out, and downed trees.Another unidentified man in Union County, Kentucky, died when his car was submerged in a ditch filled with storm water.In Knobel, Arkansas, Albert Foster, 83, died when his trailer home was blown away by storms passing through, Clay County Sheriff Terry Miller said in a post on the department's official Facebook page.Power outages, downed power poles and flooded roads were reported in the county, the sheriff's office said.Ohio Governor John Kasich issued an emergency declaration for 17 counties - along the Ohio River and in southern Ohio - "due to dangerous conditions resulting from severe storms and heavy rain.""I urge people to stay safe by staying informed, not taking any chances and checking in on your neighbors, especially seniors and families with young kids," Kasich said in a press release.Parts of Kentucky and Tennessee were under a tornado watch until early Sunday morning, according to the National Weather Service. 1809

Six people have been arrested after Saturday's apparent assassination attempt on President Nicolas Maduro in the Venezuelan capital of Caracas, the nation's interior minister said on national TV.Maduro survived the assault after several drones armed with explosives flew toward him during a speech at a military parade, an attack he blamed on far-right elements and Colombia's outgoing president, Juan Manuel Santos.Those arrested are accused of "terrorism and assassination," Interior Minister Nestor Reverol said Sunday.Reverol said one of the detained had an outstanding arrest warrant for his alleged role in the August 2017 attack on a military base in Valencia. 675

South Floridians breathed a collective sigh of relief on Sunday as Tropical Storm Isaias made a minimal impact as it traveled up the state's east coast.Once a hurricane, Isaias weakened into a tropical storm as it made landfall over the Bahamas on Saturday. And while the storm brought heavy rain, wind and storm surge to the Sunshine State, it never officially made landfall.Scripps station WPTV in Palm Beach reports that Tropical Storm Isaias caused some power outages in the area and caused rip tides off area beaches, but spared the region of major damage.Now, Isaias has its sights set on the Carolinas. In a 5 a.m. update on Monday, the National Hurricane Center said that the storm is expected to regain hurricane strength before reaching the Carolina coast early Tuesday morning. The agency said coastal areas near the North and South Carolina border could see "life-threatening storm surge."Isaias is also expected to bring flash-flood-causing rains to the Carolinas and the mid-Atlantic through the early part of this week. The National Hurricane Center urges anyone in those areas to heed the advice of local officials. 1139

Senate Majority Leader Mitch McConnell, R-Kentucky, said Thursday that he hasn't visited the White House in more than two months and noted that he's avoided visiting President Donald Trump in-person due to the White House's lax COVID-19 protocols."I actually haven't been to the White House since August the 6th because my impression was their approach to how to handle this is different from mine and what I insisted that we do in the Senate, which is to wear a mask and practice social distancing," McConnell said at an event in Kentucky on Thursday.McConnell added that he and the Trump speak "frequently" on the phone.Given McConnell's status as the most powerful lawmaker in the President's party, Thursday's revelation was surprising. In the past two months, the Senate has been negotiating more COVID-19 stimulus and begun the process of filling a Supreme Court vacancy, all while both McConnell and Trump embark on re-election campaigns that are intrinsically linked.Several White House officials have tested positive for COVID-19 in recent days, including Trump. While Trump has said that he supports masks, he himself rarely wears them, and White House officials are often spotted without them. In the days prior to testing positive for COVID-19, Trump ridiculed Democratic presidential nominee Joe Biden for wearing masks during a presidential debate.Less than a week before confirming he had contracted the virus, dozens of top Republican lawmakers visited the White House to celebrate the nomination of Judge Amy Coney Barrett to the Supreme Court. While the ceremony itself took place outdoors, many later moved indoors and were photographed shaking hands and hugging without masks or face coverings. Nearly a dozen people who were in attendance at that ceremony have since contracted the virus.USA Today also reports that after regularly testing and conducting temperature checks for visitors in the late spring and early summer, the White House eased off those protocols in recent months.Trump was hospitalized for about three full days last weekend while battling the virus but has since said he's feeling much better. McConnell said he's also seen improvement in Trump's health."I think he's perfectly fine. He seems normal," McConnell said Thursday. "And we've been discussing the very issues that you all are discussing with me right now. And of course, the biggest thing that we're doing at the moment is the Supreme Court." 2453