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SAN DIEGO (CNS) - The Collaborative Clinical Trials Unit at UC San Diego has been selected to lead and administer an international seven-year, million grant for HIV/AIDS clinical trials.The National Institutes of Health selected UCSD, along with other American, South African and Indian research hospitals, as part of its seven-year HIV/AIDS funding renewal. Every seven years, NIH competitively renews its funding of the HIV clinical trials networks operating in the United States and internationally.During the current application process, the UC San Diego AntiViral Research Center, University of Colorado Hospital, Houston AIDS Research Team and Durban International clinical research sites were chosen to work collaboratively on research priorities for the NIH/National Institute of Allergy and Infectious Diseases HIV/AIDS Adult Therapeutics Clinical Trials Network.The Chennai Antiviral Research and Treatment Center, University of Southern California and University of Miami clinical research sites were also chosen to join UCSD to serve as qualified reserve or protocol-specific sites as needed for future clinical trials."UC San Diego has helped shape HIV/AIDS research and treatment through innovative research since the inception of the adult and pediatric therapeutic clinical trials networks in 1986," said principal investigator Dr. Constance A. Benson, director of UCSD's Antiviral Research Center."Together, the seven clinical research sites selected by the NIH for the HIV therapeutic clinical trials network bring together a wealth of scientific expertise, experience and the high quality performance required to conduct complex clinical trials," she said.Abouty 38 million people are living with HIV/AIDS globally, with 1.7 million acquiring HIV in 2019 alone. In the United States, 1.2 million people are living with the virus.The UCSD-led clinical trials unit serves several regions in the United States burdened by chronic and new HIV infections as well as global regions impacted by both HIV and tuberculosis.The unit will investigate therapeutic strategies aimed at a cure for HIV, including evaluating viral persistence, researching antibody approaches to treatment and prevention and investigating treatment of inflammation and its impact on HIV comorbidities.In addition, investigators will study new drugs including long-acting drug formulations for HIV treatment and prevention, HIV-related coinfections and comorbidities -- including metabolic and end organ complications and a hepatitis B cure, as well as the treatment and prevention of tuberculosis, including TB preventive vaccines, in persons with mono- and HIV-coinfection."We are honored to lead a talented pool of investigators in a common goal of advancing research that clinically benefits people living with HIV," Benson said. 2830

SAN DIEGO (CNS) - San Diego-area elected officials mourned the death of Supreme Court Justice Ruth Bader Ginsburg, with county Supervisor Nathan Fletcher calling her death, ``a heartbreaking loss for our country.''``Justice Ruth Bader Ginsberg had a brilliant mind, compassionate heart and deep appreciation for our constitution and what American values should represent,'' Fletcher said Friday. ``I had the great honor to have lunch with her a few years back and was blown away by her intellect and playful spirit.``As a professor at UCSD, her dissent in Shelby v. Holder is a masterpiece in constitutional law. There will never be another RBG.''The court ruled in the case that the provision of the Voting Rights Act of 1965 containing the coverage formula determining which jurisdictions are subject to preclearance based on their histories of discrimination in voting was unconstitutional.In her dissent, Ginsburg wrote, ``throwing out preclearance when it has worked and is continuing to work to stop discriminatory changes is like throwing away your umbrella in a rainstorm because you are not getting wet."Fletcher's wife, Assemblywoman Lorena Gonzalez, D-San Diego, tweeted, ``My heart aches. We will truly miss the clear vision and leadership of Ruth Bader Ginsburg. Rest in Power!''Senate President pro Tempore Toni G. Atkins, D-San Diego, said ``We have lost a major force of our time. Justice Ruth Bader Ginsburg was a tireless advocate for justice, a brilliant legal mind, and an outstanding role model for generations of people.``Like millions of Americans, I join Justice Ginsburg's family in mourning her devastating loss, and honoring her legacy of feminism, equality, and progress.''Assemblyman Todd Gloria, D-San Diego, wrote, ``Our nation is better, fairer, and more just because of Justice Ruth Bader Ginsburg. Today, we pause to reflect on her extraordinary life. Tomorrow, we must do the work to ensure her legacy is not undone. Godspeed Notorious RBG.''San Diego City Council President Georgette Gomez called Ginsburg ``a trailblazing advocate for women and a voice of integrity, justice, and equality on the Supreme Court.''``Her life has inspired generations to always pursue justice for all,'' Gomez said. ``In her memory, we must keep fighting to make equality a reality in America.''Ginsburg was the second woman appointed to the Supreme Court, nominated by President Bill Clinton in 1993.The Columbia Law School graduate taught at Rutgers and Columbia and was a fierce courtroom advocate of women's rights, making her an iconic figure to feminists and earned her the nickname ``Notorious RBG.''While heading the Women's Rights Project of the American Civil Liberties Union in the 1970s, she brought a series of cases before the court that helped establish constitutional protections against sex discrimination.Ginsburg died at her home in Washington of complications from metastatic pancreatic cancer, the court announced. She was 87. 2972

SAN DIEGO (CNS) - Southwestern College President and Superintendent Kindred Murillo will retire at the end of this academic year after serving 24 years in the California Community College System, the college confirmed Wednesday.Beginning as an adjunct faculty member at Desert Community College District, Murillo has served in various roles. She spent 11 years as a chief business official and served her last nine years in the system as a college president, first at Lake Tahoe Community College District, and then at Southwestern College for more than four years."It is the commitment faculty, classified professionals and administrators have had to the success and achievement of our students that has made my career so rewarding," Murillo said. "Southwestern College has been the most remarkable community college I have had the privilege of serving during my entire academic career. We have worked together to establish a path of transformation for our students and our community."Murillo guided the college's accreditation status from warning to reaffirmation within her first year. According to a college statement, she also tackled a backlog of personnel investigations and complaints, increasing accountability at the district.Early in her tenure, she formed an Advisory Task Force on Inclusion & Race Relations that was intended to acknowledge a history of racism and inequity by design and to "develop transformative interventions designed to strengthen, enhance and support culture change," a college document said.Governing Board President Nora Vargas credits Murillo's commitment for positioning Southwestern College as a model of equity in the California Community College System."Murillo's transformative changes would have taken any other leader a decade to accomplish," Vargas said. "The work she has done will continue to benefit our students and our community for years to come. This will be her legacy."According to the college, some of her other accomplishments include:-- Implementing hiring practices, procedures and professional development that have resulted in the diversification of Southwestern College faculty, staff and administrators by almost 8%, and the leadership of the college by 14%, over a three-year span-- Moving from a 17% diverse executive leadership team to 75% diverse executive leadership-- Increasing graduation rates as measured by the College Scorecard by 10% in a little more than three years-- Entering into a partnership with San Diego State University to launch an SDSU Microsite at Southwestern College that will provide access to four-year degrees to Southwestern graduates on the Southwestern College Chula Vista campusMurillo said she is looking forward to retirement with her husband Michael and her son Vance. She lives in South San Diego County and plans on spending more time paddle boarding on the San Diego Bay and enjoying bike riding on the Bayshore Bikeway.The Southwestern College Governing Board will conduct a national search for her replacement that will include opportunity for community input. 3077

SAN DIEGO (CNS) - Police Tuesday were searching for two men who carjacked a man at gunpoint in the parking lot of the Mission Valley mall.It happened around 7:35 p.m. Monday in the parking lot of the Nordstrom Rack at 1640 Camino Del Rio North, San Diego police Officer John Buttle said.A man, whose age was not immediately available, was sitting in his blue 2007 Hyundai Sonata -- with California license plate 5XXK569 -- when two men approached the driver's side of his car, Buttle said.One of the men pulled out a black semi-automatic handgun and pointed it at the victim, demanding he give up his car, the officer said.The victim got out of the car and both men got in, then one of the men noticed the man's cell phone in the vehicle and demanded the passcode before the pair fled eastbound on Camino De La Reina in the Hyundai, Buttle said. 853

SAN DIEGO (CNS) - The San Diego County Health and Human Services Agency announced Tuesday that it will make its inclement weather shelter program available to homeless residents in the county's unincorporated areas. The agency's Housing and Community Development Services division activates the shelter when rain is expected for at least two days, reaches two inches in a 24-hour period or when a storm includes a threat of flash flooding. County officials monitor seven unincorporated zones to determine when to activate the shelter program. Homeless residents can contact 211 San Diego between noon and 7 p.m. to be connected to a shelter provider. In some cases, residents are eligible to receive assistance with transportation to an inclement weather shelter. Check 10News Pinpoint Weather storm conditions``By calling 211 people will be directed to the correct program and place,'' Housing and Community Development Services Director David Estrella said. ``We instituted the program because we know that when people are exposed to inclement weather, they are more likely to experience health issues that could be life-threatening.'' 1145

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