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The pandemic has raised awareness about convalescent plasma donation to treat coronavirus patients. But for hundreds of thousands of people who rely on regular plasma infusions to survive, a looming shortage is raising alarm bells.Mother, wife and rare disease advocate Deborah Vick lives with myasthenia gravis, a neuromuscular disorder that disrupts nerve to muscle communication.“The messages are no longer being able to reach the muscles to make them work--whether that is to walk or move or swallow or breathe--it's all interconnected,” described Vick.There is no cure, so every two weeks, she requires plasma infusions.“Being in crisis is the worst time to have to wait for treatment,” she explained. “I know, for me, my treatments are every two weeks and days before my treatment starts, my breathing is extremely labored.”Many types of primary immunodeficiency disorders like Vick’s result in an inability to produce antibodies or immunoglobulin to fight off infection.“There's about 250,000 of us in the United States alone,” said John Boyle, president and CEO of the Immune Deficiency Foundation.Canceled drives and fear of COVID-19 exposure, he says, have contributed to a drop in plasma donations for non-COVID therapy.This comes as the Red Cross says hospital distributions of convalescent plasma have increased 250 percent in November compared to September.“To not meet the rising demand is one thing, but to actually have less plasma is potentially very, very, very problematic,” said Boyle.Experts say it takes seven to 12 months to turn around plasma for patient infusion therapies. We are now nine months into the pandemic and a crisis say some could be around the corner.“There is a growing concern about the ability to meet patient clinical need,” said Amy Enfantis, president and CEO of the Plasma Protein Therapeutics Association.She says while the call for convalescent plasma therapies for COVID-19 has raised awareness, there is still an increased need for other rare-disease patients.“Our companies are making therapies every day for patients who have a perpetual need for plasma,” said Enfantis. “And that is ongoing regardless of a pandemic.”For those who rely on plasma donation and infusion treatment like Vick, it could mean the difference between life and death.“The biggest fear is not having the treatments that keep me alive. I mean, reality is I don't know what kind of life I will have, if any, how it will function without my infusions.”It’s why so many are hoping those who can, will give. 2536

The pandemic has exposed a long-standing problem across the county: a lack of internet access in homes. And for most families, the switch to virtual learning came without warning. "Yes, there was an announcement, and my initial thought was not fear, more of daunting. I was overwhelmed," said San Diego mother Paula Gosswiller. Because for Gosswiller, it meant having to convert her kitchen into a classroom for five. Ranging from ages 5 to 13, all of her school-aged kids are in different grades."We did not have internet at the time in our house, and just the thought of homeschooling without internet or technology was daunting," said Gosswiller.The kids attend St. Ritas Catholic School in southeast San Diego, which was able to secure enough devices for each student before the school year, thanks to a donation. When school went virtual, they deployed the iPads and Chromebooks to students in need."The inconsistency of internet and things like that, really made it challenging for a lot of our families," said Principal Gina Olsen. Olsen says nearly half of the students needed to borrow a device when the school went virtual. She says they were also grateful to receive a grant from the Southeastern San Diego COVID-19 Rapid Response Fund, to help cover missed tuition payments for students. Like many families, the Gosswiller's were forced to add an internet bill to their list of expenses, but not all can afford to do this."I think the statistics are something like 1 in 4 kids in the U.S. don't have access to WiFi at home. Before the pandemic, they could stay after school, they could go to a library, maybe a McDonald's parking lot or a Starbucks," said Angela Baker, who runs corporate responsibility at Qualcomm.Located in San Diego, the tech giant Qualcomm helped turned our cellphones into smartphones with its modem chips. Now, they're putting some of that technology into computers."With people getting so used to their smartphones, and the experience of always being on, great battery life, being able to use it anywhere you are, no matter where you are, we kind of took that concept and applied it to the PC market," said Pete Lancia, who runs external communications at Qualcomm. With help from manufacturing partners, Qualcomm built computers with cellular connectivity that don't require WiFi to get online. They donated 900 to students in the San Diego Unified School District."We really need to make sure that kids have access to broadband at speeds that will let them do their homework, watch videos, see the instruction if that's being done, now that we know so many schools are probably going to be online," said Baker. And like your smartphone, the battery is designed to last all day. "I think this was a wake-up call for everyone," said Gosswiller.She says her family is making it work, navigating the challenges as they go."We're ready to take it on and mark the days off the calendar when they can go back to school physically," she said. 2981

The man accused of setting a Southern California fire that has burned more than 19,000 acres appeared in court Friday and said, "It's all a lie!" as a judge read the charges against him.Forrest Gordon Clark, 51, did not enter a plea during the brief appearance in an Orange County courtroom. When the judge explained the process further to him, Clark said, "I comprehend. I do not understand though."He is due back in court August 17 for arraignment and bail review.Clark was charged Thursday with aggravated arson and criminal threats, among other offenses, in starting the Holy Fire in Cleveland National Forest that has scorched 19,107 acres and was 10% contained as of Friday night, according to forest officials. 725

The leaders of North and South Korea met Saturday for a second time, South Korea's presidency announced.North Korean leader Kim Jong Un and South Korean President Moon Jae-in held a surprise meeting at the Demilitarized Zone, the South Korean presidency said in a statement.The two leaders "exchanged their opinions" on among other things successfully carrying out a future US-North Korea summit, according to the statement. President Donald Trump canceled a June 12 summit with Kim this week, then told reporters Friday he's still open to a meeting. 558

The number of people hospitalized due to a multistate E. coli outbreak linked to chopped romaine lettuce continues to grow, the US Centers for Disease Control and Prevention said.About 53 people have been reported sickened in 16 states since March 13, the CDC said. Thirty-one of those ill have been hospitalized. Five of them developed a type of kidney failure associated with an E. coli illness called hemolytic uremic syndrome, which can be life-threatening.No deaths have been reported, the CDC said.The higher number of E. coli cases have been in Pennsylvania, Idaho, New Jersey and Montana.The outbreak has also reached consumers in Alaska, Arizona, California, Connecticut, Illinois, Louisiana, Michigan, Missouri, New York, Ohio, Virginia and Washington.Symptoms of E. coli typically begin two to eight days after consuming the bacteria, although most patients become ill three or four days after consumption. Symptoms include severe stomach cramps, diarrhea and vomiting. Most people recover in five to seven days. Those most at risk for E. coli illness include the very young, the very old and individuals with compromised immune systems.Health officials had issued a warning for residents and restaurants about chopped romaine lettuce grown in the Yuma, Arizona, area last week."Most people reported eating a salad at a restaurant, and romaine lettuce was the only common ingredient identified among the salads eaten," the CDC said in a statement."The restaurants reported using bagged, chopped romaine lettuce to make salads. At this time, ill people are not reporting whole heads or hearts of romaine," the center added.The agency recommends that people across the United States stay away from chopped romaine lettuce."Consumers anywhere in the United States who have store-bought chopped romaine lettuce at home, including salads and salad mixes, should not eat it and should throw it away, even if some of it was eaten and no one has gotten sick. If you do not know if the lettuce is romaine, do not eat it and throw it away," the CDC said.  2069