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U.S. government officials are putting an early end to a study testing an Eli Lilly antibody drug for people hospitalized with COVID-19 because it doesn’t seem to be helping them.Independent monitors had paused enrollment in the study two weeks ago because of a possible safety issue. But on Monday, the National Institute of Allergy and Infectious Diseases, which sponsors the study, said a closer look did not verify a safety problem but found a low chance that the drug would prove helpful for hospitalized patients.It is a setback for one of the most promising treatment approaches for COVID-19. President Donald Trump received a similar experimental, two-antibody drug from Regeneron Pharmaceuticals Inc. on an emergency basis when he was sickened with the coronavirus earlier this month.In a statement Lilly notes that the government is continuing a separate study testing the antibody drug in mild to moderately ill patients, to try to prevent hospitalization and severe illness. The company also is continuing its own studies testing the drug, which is being developed with the Canadian company AbCellera.Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. The experimental drugs are concentrated versions of one or two specific antibodies that worked best against the coronavirus in lab and animal tests.Lilly and Regeneron have asked the U.S. Food and Drug Administration to grant emergency use authorization for their drugs for COVID-19 while late-stage studies continue. Lilly says its request is based on other results suggesting the drug helps patients who are not hospitalized, and that it will continue to seek the FDA’s permission for emergency use.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 1928
Two SWAT team members in Florida have reportedly been suspended for choosing to respond, without permission, to a shooting at a high school in Florida where 17 people tragically lost their lives.According to the Florida Sun-Sentinel, two Miramar, Florida, SWAT team members were on duty, in the area at the time of the shooting. The SWAT officers chose to respond to the school, despite not having been told to. According to the Miramar Police Department, their decision, "created an officer safety issue and left them unaccountable for their actions," the Sun-Sentinel reports. Detective Jeffrey Gilbert and Detective Carl Schlosser were notified of their suspension on February 22, the newspaper reports. They were instructed to turn in their SWAT-issued rifles immediately. The two reportedly remain on active duty for their other assignments.Union officials are defending the actions of the SWAT officers, saying that they were following their natural instincts to help those in need when they responded to the school. “While it may have been a violation of policy to not notify their supervisors that they were going there, their intentions were brave and heroic, I think,” Police Benevolent Association President Jeff Marano told the Sun-Sentinel.On Wednesday, a Florida grand jury has formally indicted Nikolas Cruz in the Parkland school shooting. He has been charged with 17 counts of premeditated murder in the first degree and 17 counts of attempted murder in the first degree. The names of the 17 victims killed on February 14, 2018 at Marjory Stoneman Douglas High School are Luke Hoyer, Martin Duque-Anquiano, Gina Mantalto, Alexander Schachter, Alaina Petty, Alyssa Alhadeff, Nicholas Dworet, Helena Ramsay, Christopher Hixon, Carmen Schentrup, Aaron Feis, Scott Biegel, Meadow Pollack, Cara Loughran, Joaquin Oliver-Padauy, Jaime Guttenberg and Peter Wang. 1930
UPDATE: MARCH 13, 2020The County of San Diego government website on Friday is reporting eight presumptive positive cases of Coronavirus.The new number is a jump from Thursday's announcement of five new cases. Those cases include individuals on repatriation flights (2/5/20 and 2/7/20) from Wuhan, China, or from the Grand Princess cruise ship, who were placed under federal quarantine at Marine Corps Air Station (MCAS) Miramar.No other details were reported at this time. -----SAN DIEGO (KGTV) — San Diego leaders say there have been five new cases of the novel coronavirus in the county.The cases come as a Marine stationed at MCAS Miramar became the second confirmed case of coronavirus in the county by military sources. At last report, the county's first coronavirus patient was doing well.Wilma Wooten, County public health officer, detailed the new cases as:A female in her 70s who was reported to the county by the CDC. The woman was on the Grand Princess cruise ship that arrived in Oakland on Monday. The woman is at home in isolation.A male in his 50s with a history of travel to Colorado.A male in his 40s who may also have a history of travel to Colorado. He is at home in isolation.A female in her 70s who was in federal quarantine at MCAS Miramar after travel on the Grand Princess cruise ship. The woman is in the hospital in isolation.A man in his 50s who is currently hospitalized. The man may have been a case of community transmission.In addition, a public health order starting Friday will ban any mass gathering of 250 people or more through the end of March, San Diego County Supervisor Nathan Fletcher said. Gatherings that are under that limit are being asked to limit social distance to six feet at events."We are strongly recommending that they cancel all non-essential travel, that they prioritize staying in the comfort and security of their own homes, and they do everything they can to avoid large crowds," said Nick Yphantides, San Diego County chief medical officer.Mayor Kevin Faulconer also issued a State of Emergency for the City of San Diego to take advantage of financial assistance in response to combating the virus' spread."Folks we have been planning for this for decades ... and there are certain data driven triggers that give us the ability to know ahead of time if our system is stressed," Yphantides added.The county has installed about 114 hand washing stations around the region. Another 54 stations are being installed by MTS transit centers as well.Leaders also issued a new advisory to seniors 65 and older and to people with chronic illnesses to cancel non-essential activities and avoid big crowds as much as possible.RELATED: What's been canceled, postponed in San Diego, nationally due to coronavirusTo address those experiencing homelessness in the county, about 90 motel rooms have been secured to house and shelter the displaced and homeless who are infected. The goal is to avoid crowding hospitals. A task force has also been handing out hygiene kits to the local homeless population to protect against the virus.Health officials say the risk to the general public remains very low.Thursday, a fourth flight carrying passengers from the Grand Princess cruise ship was expected to land at MCAS Miramar. The base has already received about 400 passengers over multiple flights for quarantine.RELATED: Disneyland, California Adventure to close through March due to coronavirusSymptoms for the coronavirus include fever, cough, and shortness of breath or difficulty breathing. Health experts encourage people to cover their cough or sneeze, wash their hands thoroughly and often, stay home if feeling ill, avoid touching their face and mouth, and clean surfaces often to protect themselves against the virus. 3774
UPDATE: Suspect Brandon Alexander is in custody, and the Xavier Alexander and his mother are safe, Upland police say. They were found in Claremont, California, just west of Upland.SAN DIEGO (KGTV) - A 15-month-old child is missing, and police are looking for the child's father in connection with the abduction.The California Highway Patrol issued an Amber Alert Saturday night for a 2017 grey Jeep Renegade, California license plate 8DQT883.Authorities believe 31-year-old Brandon Alexander, may have kidnapped his son, 15-month-old Xavier Alexander. The pair were last seen at 5:45 a.m. Saturday in Upland, California, which is in San Bernardino County. Brandon Alexander is considered to be armed and dangerous.Brandon Alexander may have also taken the child's mother, according to Upland Police. Police say she is a white female in her early thirties. She has a restraining order against him, police said.Brandon Alexander is described as 5' 10" and 240 pounds with brown hair and blue eyes. Xavier Alexander is 2' 6" and weighs 30 pounds, also with brown hair and blue eyes. The Amber Alert was issued in Kern, Inyo, San Bernardino, Los Angeles, Ventura, Orange, Riverside, Imperial and San Diego counties.Anybody who sees the vehicle or Brandon and Xavier Alexander are asked to call 9-1-1.10News is monitoring this breaking situation. 1369
Truly heartbreaking. Stay safe, El Paso. Please follow all directions of emergency personnel as we continue to get more updates. https://t.co/BU0AH6Y8Rv— Beto O'Rourke (@BetoORourke) August 3, 2019 215