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NEW YORK (AP) — "The Magic School Bus" has traveled everywhere from Pluto to inside the human body. Now it's going somewhere new: the big screen. Scholastic Entertainment said Thursday that it will make "a feature-length, live-action hybrid film" based on the animated TV show that ran from 1994 to 1997. Elizabeth Banks will play the manic science teacher Ms. Frizzle. "The Magic School Bus," adapted from a series of books written by Joanna Cole and illustrated by Bruce Degen, centers on a group of school children who board a yellow school bus for field trips to such unlikely places as outer space or the human digestive system. 641
New research suggests that antibodies the immune system makes to fight the new coronavirus may only last a few months in people with mild illness, but that doesn’t mean protection also is gone or that it won’t be possible to develop an effective vaccine.“Infection with this coronavirus does not necessarily generate lifetime immunity,” but antibodies are only part of the story, said Dr. Buddy Creech, an infectious disease specialist at Vanderbilt University. He had no role in the work, published Tuesday in the New England Journal of Medicine.The immune system remembers how to make fresh antibodies if needed and other parts of it also can mount an attack, he said.Antibodies are proteins that white blood cells called B cells make to bind to the virus and help eliminate it. The earliest ones are fairly crude but as infection goes on, the immune system becomes trained to focus its attack and to make more precise antibodies.Dr. Otto Yang and others at the University of California, Los Angeles, measured these more precise antibodies in 30 patients diagnosed with COVID-19 and four housemates presumed to have the disease. Their average age was 43 and most had mild symptoms.Researchers found that the antibodies had a half-life of 73 days, which means that half of them would be gone after that much time. It dovetails with a previous report from China also suggesting antibodies quickly fade.The results “call for caution regarding antibody-based ‘immunity passports,’ herd immunity, and perhaps vaccine durability,” the California authors write.That’s true, Creech said, but other parts of the immune system also help confer protection. Besides churning out antibodies, B cells develop a memory so they know how to do that again if needed.“They would get called into action very quickly when there’s a new exposure to the virus. It’s as if they lie dormant, just waiting,” he said.Other white blood cells called T cells also are better able to attack the virus the next time they see it, Creech said.Although circulating antibodies may not last long, what we need to know is if and how people remake antibodies if exposed to the coronavirus again and if they protect against another infection, Alison Criss, an immunologist at the University of Virginia, wrote in an email. “We also need to know if there is a protective T cell response” that reappears.Vaccines, which provoke the immune system to make antibodies, might give longer-lasting protection than natural infection because they use purified versions of what stimulates that response, she noted.Creech agreed.“This shouldn’t dissuade us from pursuing a vaccine,” he said. “Antibodies are only a part of the story.”___Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 2967
NEW YORK CITY — Protests erupted in the Borough Park neighborhood of Brooklyn’s for a second night Wednesday over New York Gov. Andrew Cuomo's new restrictions on schools, businesses and houses of worship in the New York City "cluster zones" that are seeing an uptick in coronavirus cases.Some residents in those "cluster zones" have said the state is unfairly targeting Orthodox Jewish communities as it tries to stamp out hot spots before they spread.Cuomo and New York City Mayor Bill de Blasio have insisted the new restrictions are based solely on science and data around coronavirus-case clusters.Demonstrations turned violent Wednesday night when a journalist was allegedly attacked by a group of protesters he said surrounded him and kicked and hit him.Jacob Kornbluh, who identified himself as a reporter for jewishinsider.com, said hundreds of community members attacked him, calling him a "nazi" and "Hitler." 928
NEW YORK (AP) — Macy’s said Santa Claus won’t be greeting kids at its flagship New York store this year due to the coronavirus, interrupting a holiday tradition started nearly 160 years ago. More than a quarter of a million people come to see Santa at Macy’s in New York each year, the company said, making it hard to create a safe environment during a pandemic. Before taking a picture with the jolly old man, crowds walk in tight quarters through a maze-like Santaland that’s filled with Christmas trees, running toy trains and elves in green costumes.That makes it hard to create a safe environment during a pandemic. Santa also won’t be making in-person visits this year at its Chicago and San Francisco stores, which have similar Santalands. But he will still appear at the end of the televised Macy’s Thanksgiving Day parade, the company said.The decision by Macy’s differs from big mall owners, which will still go ahead with in-person Santa visits by banning kids from sitting on his lap and making sure they stay six feet away from him.Macy’s said it will be offering a free online experience on its website at the end of November, where families can play games and get a virtual tour of Santa’s workshop. 1222
NEW YORK CITY — The "Black Lives Matter" mural that had been painted in front of Trump Tower in Manhattan was vandalized on Monday.Police said that about 12:30 p.m. on Monday, a man dumped red paint on the large yellow mural and fled west on 56th Street. Police described the suspect as a white man wearing a black hat and a black T-shirt.The Department of Transportation repaired the mural Monday evening, Mayor Bill de Blasio said."To whoever vandalized our mural on 5th Avenue: nice try," he tweeted. "The #BlackLivesMatter movement is more than words, and it can't be undone." 588
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