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LOS ANGELES, June 5 (Xinhua) -- A latest study has found no evidence that screening for ovarian cancer may reduce the risk of dying from the disease, it was reported on Sunday.Screening, however, does increase the likelihood of unnecessary invasive procedures, according to researchers at the University of Utah.The researchers presented their findings at an on-going meeting of the American Society of Clinical Oncology in Chicago, The Los Angeles Times said.Researchers studied 78,216 women, ages 55 to 74, who participated in the National Cancer Institute's Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. Half of the women received the usual care from their OB-gyns, and half received a CA 125 screening every year for six years and an ultrasound every year for four years. They were then followed for a maximum of 12 years.The researchers observed 212 ovarian cancers in the screened group and 176 in the normal care group. There were 118 ovarian cancer deaths in the screened group and 100 in the normal care group. The differences were not statistically significant. Overall, there were 2,924 deaths from all causes in the screened group and 2,914 in the normal care group.But the researchers also observed that 3,285 women had false- positive diagnoses from the screening. Among those, 1,080 underwent surgery that included an oophorectomy (surgical removal of one or both ovaries). Fifteen percent of those who had surgery developed major complications as a result. Overall, 1,771 women in the screened group (7.7 percent) had an oophorectomy, compared with 1,304 in the normal care group (5.8 percent)."We conclude that annual screening for ovarian cancer ... does not reduce disease-specific mortality in women at average risk for ovarian cancer but does increase invasive medical procedures and associated harms," the researchers said in the study.New data presented at the meeting also showed that the widely used cancer drug Avastin can improve treatment of ovarian cancer, The Times said.About 21,880 American women are diagnosed with ovarian cancer each year and about 13,850 die from it, according to the American Cancer Society. Because it produces few symptoms, the disease is typically not diagnosed until it has become advanced and spread throughout the body. As a result, five-year survival is only about 30 percent, and the disease is one of the five most deadly cancers among women. Being able to detect the cancer at an earlier stage when it might be more curable could thus, theoretically, improve the survival rate.The tests most commonly used to detect ovarian cancer include a transvaginal ultrasound to look for tumor masses and a blood test that screens for increased levels of a tumor marker called CA 125.
WASHINGTON, Aug. 18 (Xinhua) -- Black scientists were significantly less likely than their white counterparts to receive research funding from the National Institutes of Health (NIH), according to an analysis of data from 2000 to 2006.University of Kansas Professor of Economics Donna Ginther was the lead author on the study commissioned by the NIH, which will appear Friday in journal Science.The researchers found a 10 percentage point gap in research funding -- even after taking into consideration demographics, education and training, employer characteristics, NIH experience and research productivity. For example, for every 100 grants submitted to NIH, 30 grants from white applicants were funded, compared to 20 grants for black applicants.Applications for NIH funding go through peer review that considers the significance, innovation and approach of grant applications, the investigator(s) and the research environment. About half of the applications are determined to be worth scoring. Among those scored, budgets and NIH Institutes priorities determine which applications are funded. Priorities can vary by year and by Institute.The study found that applications from black researchers were less likely to be scored and on average had worse scores. After controlling for the score of the grant, there were no race or ethnicity differences in funding.Applicants self-identify race, ethnicity and gender, but that information is not available during the peer review. However, biographical facts that are included in the review materials can provide clues to the identity of the applicants.The research suggests it is possible that cumulative advantage may explain the funding differences."Small differences in access to research resources and mentoring during training or at the beginning of a career may accumulate to become large between-group differences," the paper says.Additionally, the paper suggests further research is needed to determine why black researchers are less likely to be funded.NIH Director Francis Collins and Principal Deputy Director Lawrence Tabak call the findings unacceptable and commit to immediate action by the NIH."NIH commissioned this study because we want to learn more about the challenges facing the scientific community and address them head on. The results of this study are disturbing and disheartening, and we are committed to taking action," said Collins in an accompanying commentary. "The strength of the U.S. scientific enterprise depends upon our ability to recruit and retain the brightest minds, regardless of race or ethnicity. This study shows that we still have a long way to go."NIH initiated the study in 2008 to determine if researchers of different races and ethnicities with similar research records and affiliations had similar likelihoods of being awarded a new NIH research project grant.

BERLIN, June 1 (Xinhua) -- Germany's disease control center reported on Wednesday 365 new cases of the fatal enterohemorrhagic E. coli (EHEC), which marked a sharp rise since its outbreak in the middle of May.Twenty-five percent of the new cases involved the hemolytic- uremic syndrome (HUS), a serious complication resulting from E. coli infection that affects the blood and kidneys, Germany's Robert Koch Institute said.Until now 17 people in Europe, one in Sweden, the other in Germany have been killed by the deadly disease, while the source of the infection was still not identified.According to the data of Robert Koch Institute, at present 470 patients are suffering from HUS due to the infection, raising concerns that the death toll could be even higher in the future.Germany's Agriculture and Consumer Protection Minister Ilse Aigner defended Germany's previous alert on cucumbers from Spain on Wednesday."The fatal strain of EHEC bacteria was indeed found on Spanish cucumbers. According to the European rules, a quick warning must be sent out," she told a local TV station.Laboratory tests in Hamburg on Tuesday overthrew the previous finding that Spanish cucumbers were the sources of the outbreak.As a result of the alert, Europe and Russia imposed bans on Spanish vegetables, leaving Spanish farmers a loss of 200 million euros (287.5 million U.S. dollars) a week.Spain has expressed its intention to take possible legal actions against authorities in Hamburg and ask for compensations from Germany and the European Union.
CANBERRA, Sept. 23 (Xinhua) -- A genetic study on Friday found Aboriginal Australians are descended from the first people to leave Africa up to 75,000 years ago.Researchers from the University of Western Australia, Murdoch University and an international team analyzed genetic material of a 100-year-old West Australian Aboriginal man's hair, and found he was directly descended from a migration out of Africa into Asia.The study revealed that Australian Aboriginal ancestors split from the first modern human populations to leave Africa, between 64,000 and 75,000 years ago, at least 24,000 years before other human migrations.According to Dr. Joe Dortch, an archaeologist at the University of Western Australia, the discovery rewrites the history of the human species by confirming humans moved out of Africa in waves of migrations rather than in one single out-of-Africa diaspora.It also rewrites the story about how Aborigines arrived in Australia some 50,000 years ago."So far there are no [archaeological] sites that are over 50, 000 years old so it puts a time limit on that and focuses our future efforts," he said in a statement released on Friday.Dr. Dortch believes the finding will foster a sense of pride in modern Australian Aborigines."No-one else in the world can say 'I am descended from people who have been here 75,000 years'."Associate Professor Darren Curnoe, leader of the Human Evolutionary Biology Lab in the School of Biological, Earth & Environmental Sciences at the University of New South Wales, said the study powerfully confirms that Aboriginal Australians are one of the oldest living populations in the world, certainly the oldest outside of Africa."Australians are truly one of the world's great human populations and a very ancient one at that, with deep connections to the Australian continent and broader Asian region. About this now there can be no dispute," he told Xinhua in an email note.Meanwhile, Professor Alan Cooper, Director of the Australian Centre for Ancient DNA (ACAD) at the University of Adelaide, said while this is a major step forward, the key unresolved question remains the unique story of Aboriginal history within Australia, such as what has happened in those 50,000 years of life in the harsh Australian environment."Unfortunately, the information from a single individual tells us very little about this fascinating, and critically important part of human history. Aborigines are one of the oldest continuous human populations outside Africa, as they note in the paper, and due to the geographic isolation and limited archaeological records remain one of the most mysterious chapters in human history," he told Xinhua on Friday.The study is published on Friday in the journal Science.Indigenous Australians are the original inhabitants of the Australian continent and nearby islands. They together make up more than 2.5 percent of Australia's population.
VIENNA, Sept. 22 (Xinhua) -- Climate change and rising temperature in the long term can lead to water shortages in the Alps region, international experts warned Thursday at the Water-Scarce Final Conference in the Austrian eastern city Graz.The Alpine region originally is rich in water resources due to a large number of glaciers, spring and abundant rainfall either in summer or winter. But global warming may change this situation which has been shown in the past years that the water reserve has reduced gradually due to climate change, warned the experts.Observation data have shown a significant decrease of 25 percent in groundwater recharge in the past 100 years which has also resulted in the reduction of mountain spring.Director of the Provincial Department of Water Resources of Styria Johann Wiedner point out, in 2003, droughts occurred in the eastern part of the Alps, including the state of Styria and water shortages were also found in other regions of the Alps. He said the phenomenon was giving a warning that people "have to do something."To this end, the European Union begun a project called "Alp Water Scarce" three years ago to observe water reserves, air temperature, water temperature and water table in this region and study the relationships among them.Wiedner also admitted that there is no shortage of water at least in the short term and water supply for the local residents is totally insured.
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