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HELSINKI, July 4 (Xinhua) -- A new Finnish research shows that sleeplessness may be hereditary, and insomniacs are more likely to die earlier than people with healthy sleep patterns.The research is the first to link insomnia with mortality risk, Finnish media reported on Monday.The research is conducted by the Institute of Occupational Health in collaboration with the University of Helsinki and the Finnish National Institute for Health and WelfareIn a large-scale twin study, the Finnish researchers followed the health status of 12,500 adult twin pairs during the years from 1990 to 2009. Twenty percent of the participants were suffering from sleeplessness symptoms, including difficulty in initiating sleep, nocturnal awakening and non-restorative sleep.The study found out that compared with unidentical twins, identical twins were more likely to suffer from similar insomnia symptoms. This finding indicates that genetic factors play a role in the formation of insomnia.Moreover, the participants were divided into three groups, according to their sleep qualities. Out of the participants, 48 percent were good sleepers, 40 percent average sleepers and 12 percent poor sleepers. The search result shows that insomnia-related symptoms may increase mortality risk.In addition, compared with good sleepers, 7 percent of the women and 22 percent of the men who were average sleepers were more likely to die earlier; and poor sleepers were 1.5 times more likely to die earlier.According to the researchers, sleeplessness is a common health problem among working-age cohort. Chronic sleeplessness raises the risk of many illnesses and accidents, and thus weakens people's quality of life and ability to operate properly.The experts suggest that insomniacs should seek medical treatment in time, and chronic insomnia patients should be better treated with non-drug therapy.
LOS ANGELES, July 19 (Xinhua) -- Obesity prevalence was 30 percent or higher in 12 states of the United States last year, compared to nine states in 2009, the Centers for Disease Control and Prevention (CDC) said on Tuesday.In 2000, no states in the country had obesity rates that high, and now obesity is a problem in all 50 states, the agency said in a report based on telephone interviews with 400,000 people.Obesity rates vary by region, led by the South at 29.4 percent, followed by the Midwest at 28.7 percent, the Northeast at 24.9 percent, and the West at 24.1 percent, the report said.Mississippi had the nation's highest obesity prevalence at 34 percent, and Colorado the lowest at 21 percent, according to the report.Alabama, Arkansas, Kentucky, Louisiana, Michigan, Mississippi, Missouri, Oklahoma, South Carolina, Tennessee, Texas, and West Virginia all had obesity rates of 30 percent or higher in 2010, said the report.No state met the federal Healthy People 2010 goal of a 15 percent obesity rate. In fact, no state had a rate lower than 20 percent, the CDC said.Obesity rates have kept rising despite a steady drumbeat of warnings that obesity causes serious health problems and increases the risk of premature death, CDC officials said.An adult is considered obese if he or she has a body mass index (BMI) of 30 or greater.

UNITED NATIONS, June 9 (Xinhua) -- China on Thursday called for governments, organizations and individuals to take active actions, enhance solidarity and establish joint prevention and treatment mechanism to deal with AIDS.Yin Li, vice Health minister of China made the remarks as he addressed the United Nations High-Level Meeting on HIV/AIDS held here."As a responsible developing country, the Chinese government has actively fulfilled its commitments in achieving universal access to AIDS prevention and treatment, eliminating social discrimination, and ensuring rights to prevention, treatment and care of people living with HIV/AIDS and their families," he said.Thanks to the efforts over the years, the spread of AIDS epidemic in China has slowed down, the morality rate considerably decreased and life quality of people with HIV/AIDS has significantly improved, Yin added.In order to achieve the goal of zero new HIV infections, zero discrimination and zero AIDS-related deaths defined by the joint UN Program on HIV/AIDS (UNAIDS), China called for all countries, organizations and persons to be mobilized, further enhance solidarity and clearly define responsibilities and establish a joint prevention and treatment mechanism.Yin said that in the face of the common challenge of HIV/AIDS, the developed and developing countries must assume shared responsibilities."The developed countries should further provide developing countries with generous, unconditional financial and technical support. The developing countries should give the same priority to AIDS control as economic development, explore the models of prevention and treatment consistent with their national conditions, " he said.In addition, the private sector and relevant organizations should assume more responsibilities. On one hand, efforts should be made to mobilize more resources in better implementing prevention, treatment and care measures; on the other hand, multinational drug manufactures should reduce drugs and testing equipment prices through technology transfer, contract manufacturing and reduction of monopoly profits in order to provide universal access to treatment services, according to Yin.Yin stressed that the Chinese government would strengthen its working mechanism, enhance coordination across sectors and participation by the entire society, continue to actively participate in global fight against AIDS, assume its responsibilities and obligations so as to make contribution to achieving the goal of global AIDS control.
WELLINGTON, Aug. 30 (Xinhua) -- Middle-aged women who wolf down their meals are much more likely to be overweight or obese than women who eat slower, New Zealand research has found.In what they claimed to be the first such nationwide study anywhere, Otago University researchers analyzed the relationship between self-reported speed of eating and body mass index (BMI) in more than 1,500 New Zealand women aged 40 to 50, an age group known to be at high risk of weight gain.The study by the university's department of human nutrition could lead to new and more successful methods of treating obesity, say the researchers.Study principal investigator Dr Caroline Horwath said that after adjusting for factors such as age, ethnicity, smoking, physical activity and menopause status, the researchers found that the faster women reported eating, the higher their BMI.Results from the two-year follow-up were expected to be published next year, and if analysis confirmed a causal relationship, the researchers would test interventions that focused on encouraging women to eat more slowly.
LOS ANGELES, July 18 (Xinhua) -- U.S. scientists have proven that oncogenes can change normal cells into stem-like cells, paving the way to a safer and more practical approach to treating diseases like multiple sclerosis and cancer with stem cell therapy.In a collaborative study, researchers from the Keck School of Medicine of the University of Southern California (USC), and the Children's Hospital of Orange County (CHOC) in California and Good Samaritan Hospital Medical Center in New York have successfully converted human skin cells into brain cells by suppressing the expression of p53, a protein encoded by a widely studied oncogene. This suggests that p53 mutation helps determine cell fate -- good or bad -- rather than only the outcome of cancer.Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells.Study findings were appearing Monday on the website of the American Association for the Advancement of Science (AAAS)."The reality may be more complicated than people think," said Jiang F. Zhong, Ph.D., assistant professor of pathology at the Keck School. "What is a stem cell gene? What is a cancer gene? It may be the same thing.""When you turn off p53, people think the cell becomes cancerous because we tend to focus on the bad thing," Zhong said. "Actually, the cell becomes more plastic and could do good things, too. Let's say the cell is like a person who loses his job (the restriction of p53). He could become a criminal or he could find another job and have a positive effect on society. What pushes him one way or the other, we don't know because the environment is very complicated."Stem cells can divide and differentiate into different types of cells in the body. In humans, embryonic stem cells differentiate into three families, or germ layers, of cells. The reasons why and how certain stem cells differentiate into particular layers are not clearly understood. However, from those layers, tissues and organs develop. The endoderm, for example, leads to formation of the stomach, colon and lungs, while the mesoderm forms blood, bone and heart tissue. In its study, Zhong's team examined human skin cells, which are related to brain and neural cells from the ectoderm.When p53 was suppressed, the skin cells developed into cells that looked exactly like human embryonic stem cells. But, unlike other man-made stem cells that are "pluripotent" and can become any other cells in the body, these cells differentiated only into cells from the same germ layer, ectoderm."IPSCs (induced pluripotent stem cells) can turn into anything, so they are hard to control," Zhong said. "Our cells are staying within the ectoderm lineage."Zhong said he expects that suppressing other oncogenes in other families of cells would have the same effect, which could have critical significance for stem cell therapy. Future research should focus on determining which genes to manipulate, Zhong said.The study is slated to appear in the Proceedings of the National Academy of Sciences later this month, according to AAAS.
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