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WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.

LOS ANGELES, March 18 (Xinhua) -- The moon will move closer to Earth than it has been in more than 18 years Saturday night, space. com reported on Friday.On Saturday afternoon at 3 p.m. Eastern Daylight Time (1900 MGT) , the "supermoon", as dubbed by some observers, will arrive at its closest point to the Earth in 2011: a distance of 221,565 miles ( 356,575 kilometers) away, and only 50 minutes earlier, the moon will officially be full, the report said.At its peak, the supermoon may appear 14 percent larger and 30 percent brighter than lesser full moons (when the moon is at its farthest from Earth), weather permitting, said the report.Yet to the casual observer, it may be hard to tell the difference, according to the report.Scientists say it is a fluke of orbital mechanics that brings the moon closer to Earth.The supermoon will not cause natural disasters, such as the Japan earthquake, NASA scientists say.In December 2008, there was a near-supermoon when the moon turned full four hours away from its perigee - the point in its orbit that is closest to Earth. But this month, the full moon and perigee are just under one hour apart, promising spectacular views, depending on local conditions, the report said.

SAN FRANCISCO, May 26 (Xinhua) -- Internet advertising revenues in the United States surged to 7.3 billion U.S. dollars in the first quarter of 2011, the highest first-quarter revenue level on record for the industry, said a new report released on Thursday.The numbers also represented a 23-percent increase over the same period a year earlier, the Interactive Advertising Bureau ( IAB) and PricewaterhouseCoopers said in the report."The consistent and considerable year-over-year growth we're seeing demonstrates that digital media is an increasingly popular destination for ad dollars, and for good reason," Randall Rothenberg, chief executive officer of the IAB, said in a statement."As Americans spend more time online for information and entertainment purposes, digital advertising and marketing has emerged as one of the most effective tools businesses have to attract and retain customers," he added."These numbers indicate that the interactive advertising field hasn't simply bounced back since the recession; it's growing with dynamic energy," noted David Silverman, a partner at PricewaterhouseCoopers.IAB, a trade association for interactive marketing, comprised more than 500 media and technology companies who are responsible for selling 86 percent of online advertising in the United States.

NEW YORK, May 27 (Xinhua) -- U.S. stocks expanded gains on Friday ahead of the long Memorial Day weekend as surging commodity prices overcame disappointing economic data.European Central Bank Governing Council member George Provopoulos said that Greece might deal with its debt problem if it sticks to the aid program. That comment, which was considered as bullish by investors, drove the U.S. dollar weaker and led commodity prices surge on Friday.The stock market was driven by higher commodities prices, with thin trading volume ahead of the Memorial Day holiday, despite somewhat disappointing economic data on Friday.The Commerce Department said that both personal income and spending rose 0.4 percent in April, in line with market estimates. However, the rise in spending was the smallest in three months, suggesting the consumption situation was still weak.Meanwhile, pending home sales dropped 11.6 percent in April. The reading was a seven-month low. The market expectation was a drop of 1 percent.Moreover, the Thomson Reuters/University of Michigan Consumer Sentiment index came in above analysts' estimates. Concerns about higher gas prices and inflation had knocked the gauge down in March and April.Despite those disappointing data, analysts still held a bullish view toward the stock market. "Despite our near-term caution, we continue to see the S&P 500 reaching 1400 over the coming year," Alec Young, equity strategist of S&P Equity Research told Xinhua.According to Alex, while recent macro headwinds were raising questions about the sustainability of recent earnings momentum, he still believed that a downside trend of market was fairly limited and that the current weakness is more likely to be a correction, rather than the beginning of a new bear market."In our view, 2011 estimated EPS would have to be excessively optimistic to justify a bear market,"he added.The Dow Jones industrial average added 38.82 points, or 0.31 percent, to 12,441.58. The Standard & Poor's 500 was up 5.41 points, or 0.41 percent, to 1,331.10. The Nasdaq Composite Index rose 13.94 points, or 0.50 percent, to 2,796.86.

KIGALI, Feb. 8 (Xinhua) -- Li Zhaozhuo, vice chairman of the National Committee of the Chinese People's Political Consultative Conference (CPPCC), will head a high-level delegation to Rwanda this month to boost friendly and cooperative ties between the two countries.According to a statement released by Rwanda's Senate on Tuesday, the three-day visit will begin on Feb. 18 and is to strengthen regular contacts between Rwandan and Chinese parliamentary chambers on a number of issues and review bilateral projects.Chinese Ambassador to Rwanda Shu Zhan has confirmed that the official delegation from China is "planning an outreach visit" to Rwanda.After a meeting with the Chinese envoy to Rwanda on Tuesday, the president of Rwanda's Senate, Vincent Biruta, said his country's legislative chambers would continue to promote friendly ties with the CPPCC and play a "constructive role" in promoting bilateral cooperation.Rwanda have received training assistance from China in the applications of information communication technology (ICT) in parliaments.The Central African nation has a long-standing bilateral relationship with China in a number of socio-economic areas such as infrastructure, energy, education, health, agriculture and communications.