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BEIJING, Sept. 30 (Xinhuanet) -- Tobacco companies concealed the knowledge of radioactive substance in cigarettes from public for over four decades, a new study revealed.The revelation was made by a research team from the University of California, Los Angeles, published on Thursday in the online edition of the U.S. medical journal Nicotine and Tobacco Research.The researchers analyzed 27 timeworn documents and discovered that tobacco companies had knew the existence of polonium-210, a hazardous radioactive substance, in the tobacco since 1959.The companies studied polonium-210 throughout the 1960s, and concealed their findings about the carcinogenic potential of the radioactive substance.Hrayr Karagueuzian, the study's lead author, said the tobacco companies' deception surprised him.According to the revelation, the companies had knew the "cancerous growths" in the lungs of smokers, and even calculated how much radiation a regular smoker would inhale over 20 years.Karagueuzian and his team conducted again the study recorded in the tobacco documents and found that the radiation in cigarettes would cause up to 138 deaths for every 1,000 smokers over a period of 25 years.However, tobacco manufacturer denied that they had concealed the facts from the public.David Sutton, spokesman of Philip Morris, the largest U.S. tobacco company, said the polonium-210 was a "naturally occurring element in the air" and had been widely discussed by the public health community for years.

WASHINGTON, Nov. 25 (Xinhua) -- In the United States, the AIDS epidemic has plateaued, but it is still at "unacceptable high" level, a U.S. expert said ahead of the World AIDS Day."The situation is stable in the United States, stable in an unacceptable high level for at least 10 years and has not gone down. It's still a serious problem," Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases (NIAID), told Xinhua in an exclusive interview.According to Fauci, there are about 1.1 million people infected with HIV in the U.S., of which about 20 percent do not know they are infected. Those are the ones that more likely will infect other people. Since the world's first AIDS case was reported 30 years ago, the U.S. has seen close to 600,000 AIDS-related death. And among the 65,000 new infections each year in the U.S, about 50 percent are African Americans. In the United States, about 12 percent of the population is African American."Our new approach to prevention is to try and get access at community level, to people at most risk, to seek out to voluntarily test, to link them to care, and to automatically get them treatment," said Fauci. "When you get someone on treatment, it is extremely unlikely that they will infect their sexual partner."Fauci thought the international community's battle against the HIV/AIDS has gotten better over the last 30 years.Early on, when the disease was inaccurately thought to be a disease of developed world. There was a denial in many countries in Asia, in Southern Africa, South America and Caribbean, that this will turn out to be an extraordinary problem in those countries. As the years went by, it was clear that it was not a disease of gay men in the United States and the developed world. It was a disease mostly in the developing world when 90 percent of new infections occur in low- and middle-income countries and 67 percent of the cases are in Southern Africa."The response of the global community first was denial and not full appreciation of the potential impact of the pandemic. As the years have gone by, the response has been better and better," said Fauci, an immunologist that has made substantial contributions to research in the areas of AIDS and other immunodeficiencies, both as a scientist and as the head of NIAID.The advance in the arena of therapy with drugs has been " spectacular" and "very impressive", he said.In the early 1980 before there were any drugs, the median survival period of people in the United States who was infected with HIV, was about six to eight months. "Today in 2010, if someone was newly infected with HIV and he's 20-25 years old, and you put them on therapy, you can predict mathematically that they will live additional 50 years," said Fauci.Over the last couple of years, there has been "significant but slow" advances with vaccines against HIV. For example, there was a trial that was conducted in Thailand in which there was a modest degree of efficacy, about 31 percent of protection."That's not enough to have a vaccine available for widespread use but give us some important clues into what next generation of vaccines would be," said Fauci.As to the "three zeros" target adopted by the United Nations this year, Fauci said that it's "aspirational but not gonna be easy.""It is good to set very high goals for the future. I don't think that we realistically are gonna get to zero new infections, zero new discrimination, zero (AIDS-related) death in the next few years," said Fauci. "I think it will take several years to get there. I believe that if more countries and the international community are engaged to play a role in trying to stop HIV, to prevent and treat and care for HIV-infected individuals, that we will automatically achieve that objective."

WASHINGTON, Oct. 13 (Xinhua) -- U.S. researchers have corrected sickle cell disease in adult laboratory mice that had been bred to have the inherited blood disorder by activating production of a special blood component, according to a study published online Thursday in the journal Science.Sickle cell disease results from an abnormality in hemoglobin, the protein found in red blood cells that is responsible for transporting oxygen throughout the body. People living with sickle cell disease have two copies of an altered gene that produces sickle hemoglobin instead of normal adult hemoglobin. Sickle hemoglobin changes shape after releasing its oxygen, causing the red blood cell to become stiff, misshapen and sticky, and slowing blood flow to tissues. This process damages organs and causes pain.The study tested a new approach to increasing the production of a third form of hemoglobin -- fetal hemoglobin. Production of fetal hemoglobin predominates before birth, but turns off thereafter as adult hemoglobin production takes over. People with sickle cell disease are unable to make normal adult hemoglobin, and instead make sickle hemoglobin starting in infancy.An elevated level of fetal hemoglobin within the red blood cell reduces the tendency of sickle hemoglobin to change the shape of red blood cells. Considerable research has shown that the drug hydroxyurea increases production of fetal hemoglobin and reduces the number of pain crises and other complications of sickle cell disease in adults and children. However, not all patients respond well to hydroxyurea, and adverse side effects are a concern.The current study explores a more targeted approach to increasing fetal hemoglobin production. It builds upon earlier studies that discovered a protein called BCL11A normally suppresses the production of fetal hemoglobin soon after birth. The researchers viewed the BCL11A protein as a target for therapy and decided to see what would happen if they blocked production of the protein.The paper details how the research team silenced the mouse gene that produces the BCL11A protein in mice with sickle cell disease. Silencing the gene turned off production of the BCL11A protein and allowed the adult mice to continue to produce fetal hemoglobin. It appears to have eliminated disease symptoms without affecting other aspects of blood production."This discovery provides an important new target for future therapies in people with sickle cell disease," said Susan Shurin, acting director of the U.S. National Heart, Lung, and Blood Institute, which co-funded the study. "More work is needed before it will be possible to test such therapies in people, but this study demonstrates that the approach works in principle."Approximately 100,000 Americans live with sickle cell disease. It is most prevalent in people of African, Hispanic, Mediterranean, and Middle Eastern descent. There is no widely available cure for sickle cell disease. Bone marrow transplants have cured some patients, but the treatment is not without risk and most patients do not have relatives who can donate compatible and healthy bone marrow to them.

SAN FRANCISCO, Oct. 5 (Xinhua) -- Apple co-founder and longtime Chief Executive Officer Steve Jobs passed away on Wednesday."Steve died peacefully today surrounded by his family," Jobs' family said in a statement."We are grateful for the support and kindness of those who share our feelings for Steve. We know many of you will mourn with us, and we ask that you respect our privacy during our time of grief," said the statement.Apple's website has changed to "Steve Jobs: 1955-2011," along with the most iconic picture in which the scraggly bearded charismatic visionary posed with one hand up to his chin.Photo taken on Oct. 5, 2011 shows photo of Steve Jobs on the front page of www.apple.com. Apple Board of Directors announced that co-founder and former Chief Executive Officer Steve Jobs passed away on Wednesday"Apple has lost a visionary and creative genius, and the world has lost an amazing human being," the company said in a statement. "Those of us who have been fortunate enough to know and work with Steve have lost a dear friend and an inspiring mentor. Steve leaves behind a company that only he could have built and this spirit will forever be the foundation of Apple."Apple are asking for "thoughts, memories and condolences" to be shared by emailing rememberingsteve@apple.com.Apple Board of Directors also said in a statement that "Steve's brilliance, passion and energy were the source of countless innovations that enrich and improve all of our lives. The world is immeasurably better because of Steve."According to a memo sent by CEO Tim Cook, Apple is planning a celebration of Jobs' life for employees that will take place soon.Jobs took a medical leave of absence earlier this year, the third in his battle with pancreatic cancer that began in 2004. On Aug. 24, he stepped down as Apple CEO, saying "I have always said if there ever came a day when I could no longer meet my duties and expectations as Apple's CEO, I would be the first to let you know. Unfortunately, that day has come."Jobs recommended former CEO Tim Cook take his place as CEO. On Tuesday, Cook gave his first product announcement as CEO unveiling the new iPhone 4S.

KUNMING, Nov. 30 (Xinhua) -- More than 10,000 new HIV infections were reported in southwest China's Yunnan province during the first 10 months of this year, bringing the total number of HIV carriers and AIDS patients in the province to more than 90,000, local AIDS prevention authorities said Wednesday.As of Oct. 31, a total of 93,567 HIV infections had been reported in the province, with the disease claiming 14,340 lives, according to statistics from the Yunnan AIDS Prevention Bureau.The number of HIV infections contracted through sexual contact has been rising and sexual contact is now the main cause of the disease's proliferation, said Xu Heping, director of the bureau.Of the province's infected population, 45.8 percent contracted the disease through sexual contact, while 37.3 percent contracted the disease through intravenous drug abuse, according to the bureau.Sexually transmitted infections accounted for 77.3 percent of new infections during the January-October period, up from 71.3 percent during the same period last year, according to the statistics.Xu said this year's new infections mainly occurred in people between the ages of 20 and 39, accounting for 60.8 percent of the total.Infections among rural residents and unemployed people accounted for 55.3 percent and 18.6 percent, respectively, of this year's total, according to Xu.Lu Lin, director of the Yunnan disease control and prevention center, said migrant workers are particularly vulnerable to the disease due to their nomadic nature and lack of knowledge about the disease.China currently has 346,000 registered HIV carriers and AIDS patients, although the actual number is predicted to hit 780,000 by the end of this year, according to an expert panel consisting of members of China's Ministry of Health (MOH), the World Health Organization and UNAIDS.