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WASHINGTON, Nov. 18 (Xinhua) -- The U.S. Food and Drug Administration (FDA) on Friday approved Erwinaze to treat patients with acute lymphoblastic leukemia (ALL), who have developed an allergy to E. coli derived asparaginase and pegapargase chemotherapy drugs used to treat ALL.Acute lymphoblastic leukemia is a type of cancer in which the bone marrow makes too many lymphocytes, a type of white blood cell. White blood cells help the body fight infection and are formed in the bone marrow.Erwinaze is injected directly into the muscle three times a week and works by breaking down one of the body's protein building blocks (the amino acid, asparagine) that is present in the blood, and is necessary for the growth of all cells. Leukemia cells cannot produce this protein building block. When a patient is treated with Erwinaze the leukemia cells die. Normal human cells are able to make enough asparagine for their own needs through biosynthesis and will not be affected by treatment with Erwinaze."The approval of Erwinaze underscores the FDA's commitment to the approval of drugs for conditions with limited patient populations with unmet medical needs using novel trial endpoints," said Richard Pazdur, director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research.Side effects associated with Erwinaze treatment include serious allergic reactions, inflammation of the pancreas, high blood levels of liver enzymes, blood clotting, bleeding, nausea, vomiting and high blood sugar.

SUVA, Jan. 21 (Xinhua) -- Three in four people of the Fiji population are physically inactive causing an increase in health risks, says the country's Ministry of Health.National Advisor on Non-Communicable Disease Dr. Isimeli Tukana said that lifestyle in this Fijian generation has changed a lot, especially for the younger population that have been influenced by technology.Tukana said on Friday many children nowadays are obese and that was of growing concern. That is why the Ministry of Health is working with the Ministry of Education in promoting more physical education in schools and making it compulsory from this school term.Fiji was recently ranked the fourth-most obese nation in the region, according to the Health Ministry.Recent studies in Fiji showed a high incidence of anaemia in children, women and men.Figures released by the ministry said more than 60 percent of the island nation's population is overweight while a significant number are deficient in iron and micronutrients.The figures show that the high rate of premature disability with Non Communicable Diseases (NCD), infection and cancer has taken its toll on the population."The importance of our traditional diets, healthy eating and physical activities is paramount," a ministry statement had said."In the Pacific NCDs have reached epidemic proportions," it said."Nutritional imbalances resulting from not eating local produce instead of canned, processed food contribute to the equation, especially in these times of global economic crisis."Women's Minister Dr. Jiko Luveni has advised mothers in the country this week to stock up on healthy foods for their families.She said having green leafy vegetables was vital and buying fruits for children's snacks instead of salted prepacked ones was the way to keep the family healthy.The National Food and Nutrition Council said Friday that as the school year draws parents should find healthy alternatives for their children.They have urged teachers and parents to include fruits in every child's meal to reduce NCDs.In other countries in the region Tokelau and Nauru's obesity rates stand at 93 percent to 93.5 percent of the population.In American Samoa and Kiribati obesity stands at 81.5 percent of the population, while Marshall Islands at 80.1 percent, Federated States of Micronesia (Pohnpei) at 73.1 percent.

BEIJING, Nov. 28 (Xinhuanet) -- The U.S. FBI and police in the Philippines have arrested four alleged hackers in Manila with connections to a terrorist group in Saudi Arabia, according to media reports Monday.The four who were arrested last Wednesday hacked into AT&T Inc.'s phone systems as part of a plan to funnel money to a Saudi-based terror group, the reports said.The hackers, according to the investigators, worked for a group that helped finance a deadly 2008 terrorist attack in Mumbai, India.Investigators also said the hacking cost AT&T around 2 million U.S. dollars. And an AT&T representative told Reuters that it "ended up writing off some fraudulent charges that appeared on customer bills" but did not comment on the 2 million dollars figure."AT&T and its network were neither targeted nor breached by the hackers," AT&T spokeswoman Jan Rasmussen said. "AT&T only assisted law enforcement in the investigation that led to the arrest of a group of hackers."

BEIJING, Nov. 30 (Xinhuanet) -- Heading football frequently may cause brain damage leading to subtle but serious declines in thinking and coordination skills, a new study suggested as quoted by media reports Wednesday.Researchers used an advanced MRI (Magnetic Resonance Imaging) technique to analyze changes in brain white matter of 32 adult amateur soccer players who head balls 436 times a year on average.The study found players who head football quite frequently -- with 1,000 or more a year -- showed abnormalities similar to traumatic brain injuries suffered in car accidents."This is the first study to look at the effects of heading on the brain using sophisticated diffusion tensor imaging," said Dr. Michael Lipton, a leading researcher and associate director of the Gruss Magnetic Resonance Research Center at the Albert Einstein College of Medicine in New York City."We found the real implication for players isn't from hitting headers once in a while, but repetitively, which can lead to degeneration of brain cells," he added.The researchers compared neurological images of study participants, whose average age was 31, and found those with the highest volume of headers had abnormalities in five areas of the brain, responsible for attention, memory, physical mobility and high-level visual functions.The findings come in the wake of mixed reports on the so-called "cognitive" consequences of frequently heading soccer balls at practice.Dr. Chris Koutures, a pediatrician and sports medicine specialist in Anaheim Hills, California, said the retrospective imaging study was fascinating, but needs more data to effectively determine safe header limits, especially for younger players.Dr. Lipton agreed neuropsychological damage from headers would be hard for a coach or physician to notice since cognitive problems develop gradually, and even players might not be aware of mild memory loss."We can't tell an individual today not to be heading a ball, but caution is a good thing," Lipton said. "We need more research for definitive answers and we have the advanced imaging tools to do it."