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New York, Sept. 23 (Xinhua) -- A Chinese scientist was presented a prestigious U.S. award on Friday for the discovery of artemisinin, a drug therapy for malaria that has saved millions of lives across the globe, especially in the developing world. Pharmacologist Tu Youyou, 81, became the first scientist on the Chinese mainland to win Lasker Award, known as "America's Nobels" for their knack of gaining future recognition by the Nobel committee.Tu, a scientist at the China Academy of Chinese Medical Sciences in Beijing, pioneered a new approach to malaria treatment that has benefited hundreds of millions of people and promises to benefit many times more. By applying modern techniques and rigor to a heritage provided by 5000 years of Chinese traditional practitioners, she has delivered its riches into the 21st century."Not often in the history of clinical medicine can we celebrate a discovery that has eased the pain and distress of hundreds of millions of people and saved the lives of countless numbers of people, particularly children, in over 100 countries," Lucy Shapiro, a member of the award jury and professor of Stanford University, said while describing Tu' s discovery.Shapiro said the discovery, chemical identification, and validation of artemisinin, a highly effective anti-malarial drug, is largely due to the "scientific insight, vision and dogged determination" of Professor Tu and her team. She thought Professor Tu's work has provided the world with arguably the most important pharmaceutical intervention in the last half century."The discovery of artemisinin is a gift to mankind from traditional Chinese medicine," Tu said while receiving the award. "Continuous exploration and development of traditional medicine will, without doubt, bring more medicines to the world."

WASHINGTON, June 6 (Xinhua) -- Women who have higher levels of the appetite-controlling hormone leptin have fewer symptoms of depression, and this apparent inverse relationship is not related to body mass index (BMI), a new study finds. The results were presented Monday at The Endocrine Society's 93rd Annual Meeting in Boston, the United States."Animal data suggest that leptin may reduce anxiety and improve depression. Our study in women suggests that leptin may indeed have antidepressant qualities," said the study's lead author, Elizabeth Lawson, of Massachusetts General Hospital and Harvard Medical School in Boston.Leptin, the product of fat cells, signals satiety, or fullness. It is low in thin women and high in obese women, according to Lawson. She also said there is an increased prevalence of anxiety and depression in certain conditions in which leptin levels are typically low. These include the eating disorder anorexia nervosa, in which there is abnormally low weight and body fat, and functional hypothalamic amenorrhea, in which women have stopped menstruating despite having normal weight."It is unknown whether low leptin levels contribute to the development of mood disorders in these women," Lawson said.She and her co-workers studied the relationship between leptin levels and symptoms of anxiety and depression in 64 women. Fifteen of the women had anorexia nervosa, 12 were normal weight with hypothalamic amenorrhea, 20 were normal weight and in good health, and 17 were overweight or obese but still healthy.All subjects were asked questions to assess symptoms of depression and anxiety, with high scores indicating more symptoms. Besides measuring leptin levels in the blood, the researchers assessed the women's BMI, a measure of weight for height.The relationship between leptin and depression symptoms was independent of BMI. This finding indicates that leptin may mediate symptoms of depression and that this effect is not a function of low weight, Lawson said."Further research administering leptin to humans will be important in understanding whether this hormone has a potential role in the treatment of depression," she said.

WASHINGTON, Aug. 4 (Xinhua) -- Observations from NASA's Mars Reconnaissance Orbiter have revealed possible flowing water during the warmest months on Mars, the U.S. National Aeronautics and Space Administration (NASA) announced Thursday.Dark, finger-like features appear and extend down some Martian slopes during late spring through summer, fade in winter, and return during the next spring. Repeated observations have tracked the seasonal changes in these recurring features on several steep slopes in the middle latitudes of Mars' southern hemisphere."The best explanation for these observations so far is the flow of briny water," said Alfred McEwen of the University of Arizona, Tucson.McEwen is the principal investigator for the orbiter's High Resolution Imaging Science Experiment and lead author of a report about the recurring flows to be published in Friday's edition of the journal Science.Seven such sites on the planet have been confirmed, with 20 more possible, McEwen said."What makes these new observations so interesting is they occur at much lower latitudes where temperatures are much warmer and where it's actually possible for liquid water to exist," said Arizona State University geophysicist Phil Christensen, one of the scientists who studied the images beamed back from the orbiter.The study does not prove water exists, but identifies it as the best explanation. It's worthwhile to think about alternative reasons for these observations, but none seems to fit as well as briny water, McEwen said."I think it's going to be laboratory experiments on Earth that give us the best confirmation or refutation," he said.

SAN FRANCISCO, Aug. 2 (Xinhua) -- Social networking giant Facebook on Tuesday announced that it has bought Push Pop Press, a digital publishing company that develops the technology to help make interactive books optimized for iPad and other Apple devices."We're thrilled to confirm that we've acquired Push Pop Press, a startup whose groundbreaking software changes the way people publish and consume digital content," Facebook said in a statement.Push Pop Press was co-founded by Mike Matas and Kimon Tsinteris, both former Apple employees, and was known for teaming up with former U.S. vice president Al Gore to create a digital version of his book "Our Choice"."Although Facebook isn't planning to start publishing digital books, the ideas and technology behind Push Pop Press will be integrated with Facebook, giving people even richer ways to share their stories," Push Pop Press said in a statement posted on its website."With millions of people publishing to Facebook each day, we think it's going to be a great home for Push Pop Press," the statement added.Financial terms of the deal were not disclosed by the two companies.

HONG KONG, July 19 (Xinhua) -- A gene controlled by male hormone was critical for the growth of liver tumor, leading to a higher incidence of the disease in men than in women, according to the Chinese University of Hong Kong which made the results public on Tuesday.There is a significant gender bias in liver cancer incidence. In Hong Kong, men are three times more likely to develop liver cancer than women. Such phenomenon prompted researchers from the university to carry out a genomic location analysis in liver cancer cells starting from 2008.The researchers discovered, out of 17,000 human genes, that a gene called Cell Cycle-Related Kinase (CCRK) was directly controlled by androgen receptor. They further found that CCRK was critical for the induction of signaling pathway leading to abnormal liver cell growth and tumor formation.The results also reveal that 70 percent of patients with liver cancer were found to produce high levels of CCRK. More importantly, these patients were more likely to have late-stage cancers and lived shorter than those with low CCRK level.Using mouse models, the researchers found that either lowering the level or blocking the signaling pathway of CCRK in liver cancer cells could significantly reduce the tumor growth rate.The study has validated that CCRK is an important gene that has potential to cause liver cancer and the gene can be tested as a new targeted therapy in future.Vice-Chancellor of the university Joseph Sung, who is also team leader of the research project, said the results explained why men have a higher risk of liver cancer than women and helped push ahead with the development of a novel treatment of the disease.The above study results were published online in July in Journal of Clinical Investigation.