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BEIJING, August 1 (Xinhuanet) -- U.S. researchers have discovered a genetic mutation unique to African Americans that links to heighten their asthma risk, according to reports published on Sunday in the journal Nature Genetics.Researchers of University of Chicago found a gene, PYHIN1, and its variations may account for asthma risk in people of African descent. In their study, they examined data from nine previous genome-wide association studies, totaling more than 2 million single nucleotide polymorphisms in 3,246 asthma patients and 3,385 control patient, 1,702 patient-parent groupings, 355 family-based cases, and 468 family-based controls.In the study, the researchers found that between 26 percent and 29 percent of people of African-descent carried at least one copy of the gene. In particular, one polymorphism of the gene was 34 percent more likely found in African-American and Afro-Caribbean people with asthma. More interestingly, this variant of the gene is rarely found in Caucasian people and in Latino population, it was found in less than 5 percent.This new variant is part of a family of genes linked with the body's response to viral infections. It is thought to be involved in interferon signaling, which could influence the occurrence of asthma.The team stressed that each gene variant on its own plays only a small role in increasing asthma risk, but that risk could be multiplied when combined with other risk genes and with environmental factors.
WASHINGTON, June 14 (Xinhua) -- Short sleep duration may contribute to the development or worsening of hyperactivity and inattention during early childhood, suggests a research abstract that was presented Tuesday at SLEEP 2011, the 25th Anniversary Meeting of the Associated Professional Sleep Societies LLC.Results show that less sleep in preschool-age children significantly predicted worse parent-reported hyperactivity and inattention at kindergarten. The sample consisted of approximately 6,860 children, and analyses controlled for gender, ethnicity and family income."Children who were reported to sleep less in preschool were rated by their parents as more hyperactive and less attentive compared to their peers at kindergarten," said lead author Erika Gaylor, senior researcher for SRI International, an independent, nonprofit research institute in Menlo Park, California. "These findings suggest that some children who are not getting adequate sleep may be at risk for developing behavioral problems manifested by hyperactivity, impulsivity, and problems sitting still and paying attention." According to the authors, attention-deficit/hyperactivity disorder (ADHD) is not generally diagnosed until the school-age years. However, the onset of developmentally inappropriate inattention, hyperactivity and impulsivity is often much younger. Sleep problems, particularly difficulty falling asleep and staying asleep, are frequently reported in children and adolescents with ADHD. However, the direction of causation, if any, has been difficult to determine. Longitudinal studies may provide a window into the direction of this complex relationship.Last year at SLEEP 2010, Gaylor reported that having a regular bedtime was the most consistent predictor of positive developmental outcomes at four years of age. Having an earlier bedtime also was predictive of higher scores for most developmental measures.

JERUSALEM, July 25 (Xinhua) -- A new study carried out by a Tel Aviv University researcher indicates that the common backache may not only be caused by bad positions or aging, but also by your genes.Prof. Gregory Livshits of the Sackler Faculty of Medicine says that genes play a major role in back pain, especially in the lower back, and in spinal deterioration.In a decade-long project with 2,500 identical and non-identical twins, Livshits found that, in one Arab family, the same back problems appeared in all the members of the family, whether young or old.According to the study, non-identical twins were three times more likely to have back pain, while identical twins were six times more likely to have the same back problems.Livshits believes the discovery of the link between back pains and genes could lead to much better treatment.The research was developed in collaboration with a team of scientists at Kings College, London, led by Prof. Tim Spector and Dr. Fran Williams and was recently published in the journal " Annals of the Rheumatic Diseases."In order to better investigate the genetic causes for one of the world most common pains, Livshits and his colleagues hope to put together an international consortium of research groups.
CANBERRA, Aug. 3 (Xinhua) -- As many as a quarter of Australian women have experienced some form of assault or sexual abuse, and the higher proportion of the abuse, the higher rates of metal illness a woman tends to suffer from, a new study released on Wednesday found.Researchers from the University of Melbourne and the University of New South Wales conducted the study survey of 4451 Australian women aged 16 to 85. It looked at their experience of the four most common types of gender-based violence - sexual assault, rape, stalking and being badly beaten by their partners.About 15 percent of Australian women report sexual assault, while eight percent report rape, 10 percent said they have a stalker and eight percent report being beaten by their partner.It found strong links between those four types of violence and mental health problems including attempted suicide, posttraumatic stress disorder, panic attacks, depression, anxiety, and substance abuse.Among the women who experienced at least one form of violence, 30 percent had a mood disorder, nearly 40 percent an anxiety disorder, 23 percent were abusing substances and 15 percent were affected by posttraumatic stress syndrome.For the women who suffered higher levels of violence, the rates of anxiety disorders was 77 percent, 52 percent for mood disorders, substance abuse 47 percent and posttraumatic stress syndrome 56 percent.More than six percent of women experienced one form of violent had attempted suicide, compared to 35 percent of women who suffered at least three forms of violence.Public health expert Dr Susan Rees from the University of New South Wales' school of psychiatry, who led the research, said she is especially concerned about the suicide rate of women who are abused."What we found was that there's a high association or a strong association between exposure to gender-based violence and all the three broad classes of mental disorder - so that includes mood, anxiety, substance abuse - and a very high association with attempted suicide," she said in the report released on Wednesday."Women who've not experienced gender-based violence have about a 1.6 percent rate of attempted suicide and that increased to six percent of women who had experienced one type of gender-based violence."She said that gender-based violence was also associated with physical disability, impaired quality of life and a worsening of any existing mental disorders.Dr Rees called for the health care system, particularly psychiatric services, to work closer with women's services to improve support for victims of violence.She added that the federal government also need to underscore the importance of getting to the root cause of the violence against women by looking at attitudes towards women and gender inequality.The study was published in the Journal of the American Medical Association.
NEW YORK, July 15 (Xinhua) -- A Gallup survey released on Friday found a total of 59 percent of Americans support a ban on smoking in all public places.The July 7-10 survey among 1,016 national adults showed a change in the public's attitude toward public smoking ban. In 2001, when Gallup first asked about a ban on public smoking, 39 percent were in favor, an attitude that stayed roughly the same through 2007.At the same time, the poll also found that fewer than two in 10 people supported the idea of making smoking totally illegal.According to the American Lung Association, 27 states plus the District of Columbia have passed comprehensive smoke-free laws. A New York City law bans smoking in virtually all public places, including outdoor plazas and beaches.
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