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SAN DIEGO (KGTV) - Like Pfizer, Moderna, AstraZeneca, and many others, INOVIO Pharmaceuticals has also raced to develop a COVID-19 vaccine this year.“We’ve been working really hard to move our vaccine through the stages of clinical testing. Some things have taken a little bit longer than we hoped. I think that’s kind of always the case when you’re trying to go at great light speed,” said Dr. Kate Broderick, INOVIO Pharmaceuticals Senior VP of Research & Development based in San Diego.Broderick said with funding from the U.S. Department of Defense, the biotech company started its Phase 2 clinical trial evaluating its DNA vaccine candidate, INO-4800.The first U.S. participants received a dose of the experimental vaccine earlier this month. Approximately 400 adults in the U.S. are expected to be enrolled in the trial by the end of the month.“We hope that in the early part of 2021, we’ll be going into a really large Phase 3 trial where we’re asking the question does our vaccine protect against the disease itself,” she said.Broderick said the company hopes to enroll about 6,000 participants initially in its Phase 3 trial once they get the green light to begin.A press release from the company last week stated that “The Phase 3 segment of the INNOVATE remains on partial clinical hold until INOVIO satisfactorily resolves the FDA’s remaining questions related to the CELLECTRA 2000 device that will be used to deliver INO-4800 into the cells of the skin.”Earlier data released from Pfizer and Moderna’s studies showing high vaccine efficacy was positive news for INOVIO.“We feel that we’re in a really good place. There’s eight billion people on the planet, and we’re certainly going to need quite a few different types of vaccines to ensure everybody is protected,” she said. “The Moderna and Pfizer vaccines are RNA vaccines; ours is DNA vaccine”Broderick said one significant benefit of INOVIO’S DNA vaccine candidate is it doesn’t have to be stored in low-temperature freezers, making it easier to ship out worldwide if approved.“In fact, we can keep it at room temperature, sitting on a desk somewhere for a year with no impact,” she said.INOVIO is projecting to have 100 million doses of its vaccine ready in 2021.“With these vaccines being approved, there is definitely an end in sight, but don’t let your guard down too fast,” she said. “Unfortunately, until everyone in the country gets vaccinated, we will still have to adhere to those kinds of annoying things, wearing masks, socially distancing. I know it’s frustrating, especially before the holidays, but just keep yourself safe and the people you love safe.” 2648

SAN DIEGO (KGTV) — March 14 is bound to be a delicious day for San Diegans.Pi Day, celebrating the mathematical constant 3.14 on 3/14, routinely offers up a slew of deals from pizza pie to apple pie to chicken pot pie for customers.Ready to dig in? Lucky for you we've got more than 3.14 reasons why to love Pi Day in San Diego:Pizza dealsBJ's Restaurant and Brewhouse: Celebrate with mini one-topping pizzas for .14, valid only for dine-in on Thursday. WebsiteBlaze Pizza: Download Blaze Pizza's app and get a custom-built pizza for .14. Valid for in-restaurant orders only on Thursday. WebsitePieology: Buy one artisan thin crust pizza and get another one for .14. Download their Pie Life Rewards app and get off your next order. WebsiteFresh Brothers: Grab a personal pizza with unlimited toppings for .14 at Fresh Brothers in Carmel Valley, using the promo code "PIDAY." Valid for pick up, dine-in and delivery (but not valid with Grubhub, Postmates, UberEats, Doordash).Villa Italian Kitchen: Get a Neapolitan cheese pizza for .14 when signing up for the restaurant's loyalty program. WebsitePie deals Marie Callender's: Get a free slice of pie at Marie Callender's with the purchase of an adult entree. CouponWhole Foods: Take .14 off large bakery pies at Whole Foods locations Thursday.California Pizza Kitchen: Get a slice of Key Lime Pie for .14.Other piesSan Diego Chicken Pie Shop: North Park's Chicken Pie Shop is celebrating Pi Day, offering their famous chicken pot pie, gravy, and a roll for .14, for dine-in or to-go orders. Website 1575

SAN DIEGO (KGTV) -- Local gym owners are faced with another difficult decision as San Diego County moves into the purple tier, the most restrictive of the state’s classifications of COVID-19 spread.Under the new regulations, gyms may not operate indoors, meaning those who cannot operate outdoors will be mandated to close.The restrictions take effect Saturday.RELATED: County moves into California's COVID-19 purple tier“You want your members happy. You want your staff happy. You’ve got to put food on your table. And you’re trying to do the right thing, you’re wearing a mask and you’re indoors, so it’s going to be just an unbelievable, worrisome time,” said Bryan Welch, general manager of the Point Loma Sports Club.Welch said the new restrictions will not have a significant impact on his gym because the Point Loma Sports Club had already moved 90% of its operations outside. But he said he empathizes with gyms that do not have usable outdoor space or a cooperative landlord.Even some gym owners that can move outside may not choose to do so. They say limits would force them to operate at an untenable loss, leaving them to choose between operating indoors in violation of public health orders or going out of business. One owner, who did not wish to be identified, told ABC 10News he plans to continue indoor operations in order to stay in business.RELATED: Restrictions to hit retailers as holidays approachWhile Welch is empathetic to gyms facing that tough decision, he said he believes the only way to safely reopen all businesses is for the portion of the public that has eschewed safety measures to commit to wearing masks and social distancing.“I think your freedom actually grows. And you have to wear a piece of cloth on your face. Who cares?” said Welch. 1783

SAN DIEGO (KGTV) -- In just hours, Rady Children's Hospital is expected to get their first shipment of the Pfizer COVID-19 vaccine. It is unclear how many doses the hospital will receive, but once they arrive they will be stored in ultra low temperature freezers, until they are given to hospital staff. FedEx is in charge of making the historic delivery.The hospital's chief operating officer, Dr. Nicholas Holmes, says most of the hospital's staff wants to get the vaccine. It will not be mandated, since it's only approved for emergency use. The first to get the vaccine at the hospital will be front-line healthcare workers in the 1-A category. The category includes physicians, respiratory therapists, nurses, and other staff who have high chances of exposure to the virus. Dr. Holmes says a team at the hospital spent the last four days planning the logistics for distribution. Staff working in the same departments will get the vaccines on a rolling basis, just in case they experience side effects and to prevent an entire department from having to miss work at once. Once the staff receives it's first dose, they'll get a second dose 21 days later. 1166

SAN DIEGO (KGTV) - It was an emotional day in a Southern California courtroom for the family of a murdered Army veteran.Nearly 20 people who were close to Julia Jacobson read victim-impact statements during the sentencing hearing for her killer, ex-husband Dalen Ware.Julia’s brother, Tony Jacobson, spoke exclusively with 10News reporter Jennifer Kastner. “It was kind of both a celebration to her as well as an understanding that this isn't just some random person. It really is someone that truly did touch her community, served her country and people really did love her very much. Unfortunately, [Ware] took her away from us all,” says Tony Jacobson of his own impact statement that he read in the courtroom.RELATED: Ex-husband of former Army veteran pleads guiltyWare will serve 15 years to life in prison, after pleading guilty to her murder. It was more than a year ago that the retired Army captain and her dog disappeared over Labor Day weekend.Her SUV was discovered abandoned near her home in University Heights. Ware was later arrested in Phoenix where he was living, and charged with her murder.Her remains were discovered in a shallow grave, in Riverside County. Even though Monday’s sentencing was painful, it still brought back a flood of positive memories for the Jacobson family, as they shared old stories.RELATED: Police searching for Julia Jacobson find remains“One of them that I remember so vividly just came rushing back to me. When she would laugh, she would snort a little bit which was makes it sound so embarrassing for her but it was one of her things that made her so personable,” adds Tony. What's next for the Jacobsons remains unclear.“I don’t know if there's really ever closure in something like this. The fact that Dalen has 15 years to life just tells me that in roughly 14 years we’ll have to revisit this again,” says Tony. 1896