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Their youthful brains were developing normally, with no signs of developmental, psychological or neurological problems. None had ever had a concussion. But by the end of a single football season, 24 children between the ages of 9 and 18 who had more frequent impacts to the head showed signs of damage to brain development, new research says."Repetitive head impact exposure may have a cumulative effect in the rapidly developing brains of youth and high school football players," said study co-author Gowtham Krishnan Murugesan, a radiology research assistant at UT Southwestern Medical Center in Dallas, adding that the results mirror other recent findings.The study outfitted 60 youth and high school football players who had no history of head trauma or developmental issues with a head impact telemetry system that measures the magnitude, location and direction of impacts to the head. The researchers were not looking at whether the impact resulted in a concussion, only that impact occurred.The children were sorted into two categories: high cumulative head impact players (24) and low cumulative head impact players (36).Before beginning to play, each child had a resting state functional scan, known as an fMRI; the scans were repeated at the end of football season. The researchers were trying to see how exposure to repetitive hits affects the normal "pruning" process in the brain that occurs during adolescence."Pruning is an essential part of brain development," Murugesan said, comparing the process to how a tree needs to have dead or unneeded branches cut to keep it healthy and allow it to grow."Disruption in normal pruning has been shown to be related to weaker connections between different parts of the brain," he said.After comparing the functional MRI results to the player's level of impact, the researchers found that youth in the high-impact group had damage to their brains' pruning process after one season."Our study has found a significant decrease in gray matter pruning in the frontal default mode network, which is involved in higher cognitive functions, such as the planning and controlling of social behaviors, " Murugesan said.Although the "teenage years are a critical time for brain development, brain remodeling or synaptic pruning, this was a short-term study and did not follow the players longitudinally over several years. We don't really know the full application," said Dr. Julian Bailes, director of neurosurgery and co-director of the NorthShore University HealthSystem Neurological Institute, who was not involved in the research.Weill Cornell neurologist Dr. Richard Isaacson, who was also not involved in the study, called the research "early" and said the results don't necessarily "translate to a clinical or cognitive outcome." More research is needed to see whether the decline in brain pruning permanently affected the child's cognitive function or whether the brain's natural plasticity allowed it to repair itself."I would call this a pilot study," Isaacson said. "The call to action would be that we need more robust longitudinal studies with a pre- and a post-assessment of more than brain imaging. The study should also measure cognitive and neurological function and look for changes."As we learn more about the issue, Isaacson said, parents should do everything they can to limit contact in sports, "especially in practice before games, where studies show the majority of contact occurs." 3464

Three UCLA basketball players accused of shoplifting in China last week were flying back to Los Angeles on Tuesday, the commissioner of the Pacific-12 athletic conference said, hours after US President Donald Trump said he asked his Chinese counterpart to help in the case.The three freshmen -- LiAngelo Ball, Cody Riley and Jalen Hill -- were allowed to leave China on the US-bound flight after the situation was "resolved to the satisfaction of the Chinese authorities," said Larry Scott, commissioner of the Pac-12 Conference, of which UCLA is a member."We are all very pleased that these young men have been allowed to return home to their families and university," Scott said in a news releaseThe three were arrested last week while their team was in the Chinese city of Hangzhou ahead of the squad's season opener in Shanghai. They were questioned on suspicion of stealing sunglasses from a Louis Vuitton store near their hotel.The trio stayed at the hotel, reportedly awaiting next steps in their case, while their teammates went to Shanghai, where UCLA defeated Georgia Tech 63-60 on Saturday. The three also remained in China as their team returned to the United States over the weekend.Scott did not say how the case was resolved; a conviction of grand larceny in China could result in years of prison. But Trump said Tuesday that he had asked Chinese President Xi Jinping to help.UCLA's trip coincided with Trump's two-day state visit to the Chinese capital, Beijing, as part of his 13-day trip to Asia. Trump told reporters Tuesday that Xi had been helpful in working to resolve the case.Scott acknowledged Trump, among others, in his statement."We are grateful for the role that our Chinese hosts played, and for the courtesy and professionalism of the local authorities," Scott said. "We also want to acknowledge UCLA's significant efforts on behalf of their student-athletes."Finally, we want to thank the President, the White House and the US State Department for their efforts towards resolution."Trump's request was first reported by the Washington Post.  2086

There are now 286 cases of possible and confirmed acute flaccid myelitis in the United States this year, according to the US Centers for Disease Control and Prevention.That includes 116 confirmed cases of the rare polio-like illness, also known as AFM, that leads to sudden onset of paralysis. That's 10 more confirmed cases than the agency reported a week ago. An additional 170 possible cases of AFM are under investigation.More than 90% of the 440 patients with AFM since 2014 have been children younger than age 4. Most of the children with confirmed cases experienced a viral illness with symptoms including fever and cough about three to 10 days before the onset of paralysis, the CDC said this month. 715

The Boston Red Sox made sure to savor their Game 4 win over the New York Yankees in the American League Division Series on Tuesday.The Red Sox played Frank Sinatra's edition of "New York, New York," a staple at Yankee Stadium, as they celebrated advancing to the American League Championship Series.Boston was merely returning the favor after Yankees star Aaron Judge had the song echoing throughout the inside of Fenway Park following New York's Game 2 victory on Saturday.The Yankees nearly erased what had been a 4-0 deficit Tuesday. They scored two runs in the ninth inning off Red Sox closer Craig Kimbrel and had the tying and go-ahead runs on base when Gleyber Torres grounded out to end the game.The Red Sox are headed to the ALCS for the first time since their World Series victory in 2013.  833

Those with half-a-million dollars to spend on a car could bid on a custom Lamborghini that belongs to Pope Francis.The  Huracán RWD Coupé was given to the Pope from Lamborghini last year, and he plans to auction it off via Sotheby's, according to the Vatican. Esquire reports 70 percent of the proceeds will go to Nineveh, a city in Iraq that is under siege by ISIS.See a photo of the Pope and his LamboThe rest will be divided among "Amici per il Centrafrica Onlus," Groupe International Chirurgiens Amis de la Main, and the Pope John XXIII Community Association, Esquire reports.The Pope's Lamborghini goes 198 miles per hour. It is expected to bring in between 0K and 5K, according to Sotheby's, which will do the auction on May 12. 784