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BERLIN, June 1 (Xinhua) -- Germany's disease control center reported on Wednesday 365 new cases of the fatal enterohemorrhagic E. coli (EHEC), which marked a sharp rise since its outbreak in the middle of May.Twenty-five percent of the new cases involved the hemolytic- uremic syndrome (HUS), a serious complication resulting from E. coli infection that affects the blood and kidneys, Germany's Robert Koch Institute said.Until now 17 people in Europe, one in Sweden, the other in Germany have been killed by the deadly disease, while the source of the infection was still not identified.According to the data of Robert Koch Institute, at present 470 patients are suffering from HUS due to the infection, raising concerns that the death toll could be even higher in the future.Germany's Agriculture and Consumer Protection Minister Ilse Aigner defended Germany's previous alert on cucumbers from Spain on Wednesday."The fatal strain of EHEC bacteria was indeed found on Spanish cucumbers. According to the European rules, a quick warning must be sent out," she told a local TV station.Laboratory tests in Hamburg on Tuesday overthrew the previous finding that Spanish cucumbers were the sources of the outbreak.As a result of the alert, Europe and Russia imposed bans on Spanish vegetables, leaving Spanish farmers a loss of 200 million euros (287.5 million U.S. dollars) a week.Spain has expressed its intention to take possible legal actions against authorities in Hamburg and ask for compensations from Germany and the European Union.

SAN FRANCISCO, July 19 (Xinhua) -- Apple Inc. on Tuesday reported strong third fiscal quarter results that top analysts' expectations, citing strong iPhone and iPad sales.For its fiscal 2011 third quarter ended on June 25, Apple reported net income of 7.31 billion U.S. dollars or 7.79 dollars per share, compared with 3.25 billion dollars, or 3.51 dollars per share a year ago.Its revenue reached 28.57 billion dollars, compared with 15.7 billion dollars in the same period a year earlier. International sales accounted for 62 percent of the quarter's revenue.The average estimate is a profit of 5.84 dollars a share on revenue of 24.9 billion dollars.The Cupertino, Califronia-based company sold 20.34 million iPhones in the quarter, representing 142 percent unit growth over the year-ago quarter. It sold 9.25 million iPads in the third quarter, a 183 percent unit increase on a year-over-year basis.The only drawback is the sales of iPods, which had a 20 percent unit decline to 7.54 million from the year-ago quarter."We're thrilled to deliver our best quarter ever, with revenue up 82 percent and profits up 125 percent," Steve Jobs, Apple's chief executive officer, said in a statement."Right now, we're very focused and excited about bringing iOS 5 and iCloud to our users this Fall," added Job.It is the first time since 2008 that Apple's third-quarter earnings does not include the release of a new iPhone, which, slated for launch in September, is reportedly to be thinner and lighter with a faster chip and 8-megapixel camera.Apple has enjoyed double-digit year-over-year percentage revenue growth for the past four quarters. It had previously beaten the average earning projection for at least 29 straight quarters, according to data compiled by Bloomberg.For the fourth fiscal quarter of 2011, Apple's chief financial officer Peter Oppenheimer said the company expects revenue of 25 billion dollars and earnings per share of about 5.5 dollars. Apple has been known for its conservative projections of earnings.Apple has been operating without the daily attention of Jobs since the CEO took a medical leave this January. The Wall Street Journal reported Tuesday that some members of Apple's board have discussed CEO succession with executive recruiters and at least one head of a high-profile technology company.But the people familiar with the matter told the newspaper that it was more of an informal exploration of the company's options and don't appear to have been acting on behalf of the full board.Meanwhile, Apple has recently been busy with a number of legal battles over patent rights with HTC, Eastman Kodak and Samsung.Last week, the U.S. International Trade Commission made an initial ruling that HTC infringed two of Apple's phone patents in its smartphones powered by Google's Android operating system.If upheld, the ruling could let Apple force other Android phone makers to pay significant patent fees.On Tuesday, Google's executive chairman Eric Schmidt said at a conference in Tokyo that Apple's smartphone lawsuits are inspired by jealousy and a lack of innovation in iPhone, noting Google would support HTC's fight against Apple and was confident of a win.

WASHINGTON, July 5 (Xinhua) -- Intake of high levels of folate, a water-soluble B vitamin that occurs naturally in food, may reduce colorectal cancer risk, according to a new study published Tuesday in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute. "We found that all forms and sources of folate were associated with lower risk of colorectal cancer," said lead author Victoria Stevens, of the American Cancer Society. "The strongest association was with total folate, which suggests that total folate intake is the best measure to define exposure to this nutrient because it encompasses all forms and sources."Total folate includes naturally occurring food folate and folic acid from fortified foods and dietary supplements.The research team investigated the association between folate intake and colorectal cancer among 99,523 participants in the Cancer Prevention Study II Nutrition Cohort; a total of 1,023 participants were diagnosed with colorectal cancer between 1999 and 2007, a period entirely after folate fortification began. Neither higher nor lower risk was observed during the first two years of follow-up (1999 to 2001), while associations were statistically significantly inverse for the subsequent years (2002 to 2007). The findings of this study add to the epidemiologic evidence that high folate intake reduces colorectal cancer incidence.Folates are essential nutrients needed to make components used for functions required for normal cell growth, including DNA synthesis and repair. Because these processes are critical for cell growth and differentiation, the relationship between folate intake and cancer development has been investigated in several cancers, and most extensively in colorectal cancer.

LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

PARIS, June 19 (Xinhua) -- Commercial Aircraft Corporation of China Ltd. (Comac) on Sunday set up its European office in Paris, the second overseas branch after its U.S. office, marking a new step for China's aviation industry in opening-up and international exchanges."The establishment of Comac Europe office is very significant. It represents the strategic cooperation between China and France and will deepen the two sides' collaboration in aerospace and all areas concerned," Chinese Ambassador Kong Quan said at an opening ceremony, citing Europe's influence in global aerospace industry and civil aviation market."Taking self-dependent innovation as the strategic cornerstone, Comac meanwhile actively conducts international cooperation and draws upon advanced technologies and experience in global civil aviation industry...," Comac President Jin Zhuanglong said.French Secretary of State for Transport Thierry Mariani (4th L), Chinese Ambassador to France Kong Quan (3rd L) and General Manager of the Commercial Aircraft Corporation of China (COMAC) Jin Zhuanglong (2nd R) attend the unveiling ceremony of COMAC Europe Office in Paris, France, June 19, 2011. The COMAC Europe Office was offically opened here Sunday.The Chinese aerospace manufacturer has built up cooperative relationship and partnership with dozens of enterprises and institutions in many countries and regions since its establishment in May 2008 in Shanghai.Regional jet ARJ21 and the trunkliner C919 are two flagship products of the young Chinese company. The group is now working to achieve certification and delivery of ARJ21-700 aircraft by the end of this year, Jin said.With regard to China's C919 trunkliner program, Jin said COMAC has signed cooperation agreements with 17 international companies in the United States and Europe, and has actively explored collaboration with GECAS, British Airways and Ryanair."In the context that the world economy is on recovery from the financial crisis, the civil aviation industry is facing great challenge. We are willing to keep close contact with all relevant public administrations and forge friendly relations and cooperation with overseas suppliers to contribute to the development of world civil aviation industry," Jin said.For the French State Secretary for Transport Thierry Marianne, who also attended the opening ceremony, the Chinese aviation market has great potential in the years to come, and China is estimated to need 3,000 new planes."We have understood that China had decided to build its own aerospace industry. It is a legitimate choice," Marianne said.A demo mock-up of the full-scale forward fuselage of C919 will be displayed during the 49th Paris Air Show on June 20-26, which will be the first time that the 1:1 demo mock-up is to be showcased at an international stage outside China, Jin told Xinhua.During the air show, Comac is going to sign agreements with an international airline and an airborne-system supplier and carry out a series of activities concerning international cooperation and exchanges, according to the group.

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