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LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).
VANCOUVER, Sept. 17 (Xinhua) -- The fourth International Health Qigong Tournament and Exchange kicked off the competition portion of the Vancouver event Saturday to showcase the health benefits of this increasingly popular activity.At a gala opening ceremony in the War Memorial Gymnasium at the University of British Columbia, the biennial tournament was being held outside of China for the first time in an effort to promote the exercise that involves controlled breathing, body postures, movement and mental concentration.The Vancouver tournament has attracted 44 Health Qigong groups from 25 countries and regions, 327 participants in all. The event was last held in Shanghai in 2009.Xiao Min, the All-China Sports Federation vice president, said after three successful events in China, it was important to explore the possibilities of rotating the host venues around the world to boost the exposure of Health Qigong to a wider audience, effectively strengthening the interaction of the Eastern and Western cultures.Calling it "one of the best Chinese traditional sports," Xiao added, "we still have a long way to go in promoting Health Qigong. However, we will try our best to promote it so as to bring health benefits to more people in the world."Sending a message read by Vancouver-based federal politician Wai Young, Canadian Prime Minister Stephen Harper said such a tournament would allow people to "cultivate their interest in and learn more about the benefits of this ancient Chinese healing system.""I would like to commend the organizing committee for putting together a program that promotes cultural exchange and encourages others to embrace Qigong teachings and practices for health, fitness and personal growth. I'm certain that the enthusiasts will make the most of this exciting opportunity and will leave inspired to put what they have learned into practice," wrote Harper, who will be making his second official visit to China later this year.In his speech to the dignitaries and public gathered for the opening ceremony, Liang Shugen, the Chinese Consul General in Vancouver, said it didn't matter who won medals during the competition as everybody participating was a winner."However, it is all the more important that your group build up friendship among the different peoples from different countries, so therefore I wish you all do your best and hope that through this competition you bring the friendship of the Chinese people, of the people from different countries, back to your home country and it is such a course that will be building a harmonious world."With participants representing countries and regions from North America, Europe, Australia, South America, Asia and all over China, which has competitors from 10 provinces, as well as Macau and Hong Kong, the eight-day tournament is providing an extensive overview of what Health Qigong is about.In addition to the two-day competition taking place over the weekend, there is also a referee clinic, a Duan examination and training sessions in the different Health Qigong disciplines, Yi Jinjing, Wu Qinxi, Liu Zijue and Ba Duanjin, among them.Ken Low, who is considered Mr Wushu in Canada, has been instrumental in organizing the Vancouver event. As the president of the Canada International Health Qigong Association he said people need to know about what's involved in the exercise and how it's different from traditional martial arts."It is more than fitness, it's actually mental and physical. It builds inner strength and it builds your, strengthens your joints and muscles and tendons, particularly in your neck area, your shoulders, your spine and your inner organs and your breathing and your focus," he said."So it's not a martial arts, although it is connected somewhat to martial arts because the movements have no self-defence meanings. All the movements are designed to enhance your health."One person who turned to the exercise for health reasons is Diane Hynes. A member of the 12-strong team representing the USA Health Qigong Association, the 50-year-old New Jersey native offers classes in Health Qigong with a cliental of students ranging from five to 84 years.She explained Qigong "helps refine that movement of our eternal energy and makes more as you breathe and move. It has to do with your breath, your ability to relax, bringing your mind to your heart and really moving it out, the energy out to the limbs. That's why it helps with sleep and stress."Hynes, who looked healthy and fit, said she realizes that she is influencing others who want to know what the mother of nine-year-old is doing to look good."And I'm not taking drugs to look well or having surgery," she said, adding the practice is destined to get bigger among westerners as the Baby Boomer generation ages and puts greater emphasis on health. ( "Medication can help for awhile but that takes from you as well, that takes from your energy. This just helps to build energy and move it in your body. Because the thing is, in Chinese medicine, it's about movement, everything's a flow and moving in a circle so it's a give and take."It's a movement and if you are not moving in harmony and you're stuck and stagnant then you are going to be uneasy or diseased or unwell. You're not necessarily sick but you're stuck."

BEIJING, Aug. 24 (Xinhuanet)-- A new study shows that a diet rich in cholesterol-friendly foods, such as soy products and tree nuts, can decrease LDL (bad) cholesterol significantly, according to media reports on Tuesday.The study, published in the Journal of the American Medical Association, found that people who ate a healthy diet filled with cholesterol-lowering foods experienced a 13 percent decrease in their LDL cholesterol levels.For patients with high levels of so-called bad cholesterol, doctors usually have two prescriptions: cholesterol-lowering statin drugs and a diet that cuts out foods high in saturated fat, such as ice cream, red meat and butter.But the new study found that when it comes to lowering artery-clogging cholesterol, what you eat may be more important than what you don't eat.David Jenkins of St. Michael's Hospital and the University created the "portfolio diet," which includes regular consumption of tree nuts and high amounts of fiber from oats, barley and vegetables. The diet, which replaces butter with plant sterol-enriched margarine and substitute soy-based products for meat, allows maximum benefit in lowering cholesterol and preventing heart disease. "The study highlighted the power of food to lower risk for cardiovascular disease: What you do eat and what you don't eat are both important," said Dr. Jane Klauer, a New York internist specializing in metabolism and nutrition.A high overall cholesterol level makes a person nearly twice as likely to suffer a heart attack or stroke as someone whose total cholesterol falls into a healthy range.
SAN FRANCISCO, Sept. 13 (Xinhua) -- Microsoft released on Tuesday a test version of Windows 8 to developers, posing to regain ground of the tablet market dominated by Apple and Google.At its developer-focused BUILD conference held in Anaheim, California, the software giant handed out new Samsung tablet computers with a test version of the code-named "Windows 8," the first detailed preview of the system for developers and people outside Microsoft.Generally expected to be launched in fall 2012, Microsoft did not say when the system will ship or its price.Microsoft Windows President Steven Sinofsky introduces the new tablet running a test version of its touch-enabled Windows 8 at the Build conference in Anaheim, California September 13, 2011Featuring a home page filled with colorful application tiles, the new system boots up in seconds. Microsoft said the system will run on low-power ARM-based chips that power smartphones and tablets. Windows 8 also introduces a new "Metro style" interface, which run full-screen and users can multitask in two at a time."We reimagined Windows," said Steven Sinofsky, president of the Windows and Windows Live Division at Microsoft, in his keynote address to the thousands of developers in attendance. "From the chipset to the user experience, Windows 8 brings a new range of capabilities without compromise."Analysts said the new system is consumer-oriented and intuitive but it will take time to see whether it is an "iPad killer."As professionals and consumers began to spend more time on smartphones and tablets, Microsoft has not got a significant bite of the market, losing ground to Apple's iPad and devices running Google's Android system.
WASHINGTON, Aug. 4 (Xinhua) -- Researchers have found a way to turn mouse embryonic stem cells into sperm and this finding opens up new avenues for infertility research and treatment, according to a study published Thursday in the online edition of journal Cell,A Kyoto University team coaxed mouse embryonic stem cells into sperm precursors, called primordial germ cells (PGCs), and shown that these cells can give rise to healthy sperm. The researchers say that such in vitro reconstitution of germ cell development represents one of the most fundamental challenges in biology.When transplanted into mice that were unable to produce sperm normally, the stem cell derived PGCs produced normal-looking sperm, which were then used to successfully fertilize eggs. These fertilized eggs, when transplanted into a recipient mother, produced healthy offspring that grew into fertile male and female adult mice. The same procedure could produce fertile offspring from induced pluripotent stem cells that are often derived from adult skin cells."Continued investigations aimed at in vitro reconstitution of germ cell development, including the induction of female primordial germ cell-like cells and their descendants, will be crucial for a more comprehensive understanding of germ cell biology in general, as well as for the advancement of reproductive technology and medicine," the researchers wrote.
来源:资阳报