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发布时间: 2025-05-28 01:39:31北京青年报社官方账号
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  濮阳市东方医院看病专业   

  濮阳市东方医院看病专业   

SAN FRANCISCO, June 20 (Xinhua) -- Google and the British Library announced Monday that the Internet search giant will digitize 250,000 out-of-copyright books from the library's collections, making up to 40 million pages from 1700 to 1870 available to the public online.In a joint statement, the British Library and Google said they will work in partnership over the coming years to deliver the content free through Google Books and the library's website, and full text search, download and reading will be available. Google will cover all digitization costs.The project is going to cover a huge range of printed books, pamphlets and periodicals dated 1700 to 1870, a period of political and technological turmoil, from the Industrial Revolution to the French Revolution, from the introduction of the income tax in Britain and the invention of the telegraph and railway.It will include material in a variety of major European languages and will focus on books that are not yet freely available in digital form online, said the statement.Since December 2004, Google has announced partnership with some 40 high-profile university and public libraries, planning to digitize and make available some 15 million volumes within a decade through Google Books service.The project has triggered controversy as publisher and author associations oppose the plan to put copyrighted titles online in a class action lawsuit.

  濮阳市东方医院看病专业   

WASHINGTON, July 13 (Xinhua) -- Human neural stem cells are capable of helping people regain learning and memory abilities lost due to radiation treatment for brain tumors, a University of California, Irvine (UCI) study suggests.Research with rats found that stem cells transplanted two days after cranial irradiation restored cognitive function, as measured in one- and four-month assessments. In contrast, irradiated rats not treated with stem cells showed no cognitive improvement."Our findings provide solid evidence that such cells can be used to reverse radiation-induced damage of healthy tissue in the brain," said Charles Limoli, a UCI radiation oncology professor.Study results will appear Friday in Cancer Research, a journal of the American Association for Cancer Research.Radiotherapy for brain tumors is limited by how well the surrounding tissue tolerates it. Patients receiving radiation at effective levels suffer varying degrees of learning and memory loss that can adversely affect their quality of life."In almost every instance, people experience severe cognitive impairment that's progressive and debilitating," Limoli said. " Pediatric cancer patients can experience a drop of up to three IQ points per year."For the UCI study, multipotent human neural stem cells were transplanted into the brains of rats that had undergone radiation treatment. They migrated throughout the hippocampus -- a region known for the growth of new neurons -- and developed into brain cells.Researchers assessed the rats one month and four months after transplantation, noting enhanced learning and memory abilities at both intervals.Additionally, they found that transplanting as few as 100,000 human neural stem cells was sufficient to improve cognition after cranial irradiation. Of cells surviving the process, about 15 percent turned into new neurons, while another 45 percent became astrocytes and oligodendrocytes -- cells that support cerebral neurons.Most notably, Limoli said, he and his colleagues discovered that about 11 percent of the engrafted cells expressed a behaviorally induced marker of learning, indicating the functional integration of those cells into memory circuits in the hippocampus."This research suggests that stem cell therapies may one day be implemented in the clinic to provide relief to patients suffering from cognitive impairments incurred as a result of their cancer treatments," Limoli said.

  

BEIJING, June 20 (Xinhuanet) -- More Chinese cities have seen month-on-month declines in the prices of both new and secondhand homes, according to the National Bureau of Statistics (NBS) on Saturday.The NBS said in a statement on its website that month-on-month price growth for new commercial homes was reported in 50 out of the NBS's statistical pool of 70 major cities. That compared to 56 cities reporting month-on-month growth in April.New home prices declined from a month ago in nine cities and stood unchanged in 11 cities, while 27 cities posted smaller monthly price gains, said the NBS.As for resold housing units, 23 cities reported second-hand home price declines month-on-month in May, up from 16 in April. Secondhand home prices stayed unchanged in 11 major cities in May from April, according to the NBS.On a year-on-year basis, the prices of new commercial homes declined in three cities, including Hangzhou and Sanya, both of which were hot spots for real estate speculation in the past. Meanwhile, 36 cities saw lower year-on-year growth, up from 29 in April, said the NBS.Secondhand home prices dropped in four cities from one year ago, while 29 cities reported declines in year-on-year price growth from April.The NBS stopped releasing overall housing prices for 70 major cities in January, citing the fact that overall price figures for the cities failed to reflect regional differences. The NBS is also using a new surveying method to determine price changes.The government has adopted various measures to cool the property market and curb rising prices, including restricting residents in major cities from buying second or third homes, requiring higher down payments for mortgages and instituting new property taxes in the cities of Chongqing and Shanghai.But there has not been a significant drop in home prices. The latest central bank survey of urban bank depositors found that more than one-third of respondents anticipated home prices would remain stable in the second half of the year.The survey, which is carried out quarterly among 20,000 urban bank depositors in 50 major cities, said 25.9 percent of respondents believed prices would continue to rise, while only 18.9 percent expected a decline.Meanwhile, the survey showed that 74.3 percent of residents said housing prices in the second quarter were "too high to afford", almost the same as during the first quarter.Experts and market observers said the Chinese property market is stagnant with home transactions remaining grim and no clear trend in prices.Yang Hongxu, an analyst with the Shanghai-based E-house China Research and Development Institute, said the May figure has continued April's downward trend in prices, but the cooling of the market will happen gradually.The NBS announced on Tuesday that property developers sold 329.32 million square meters of commercial houses nationwide in the first five months of this year, an increase of only 9.1 percent year-on-year.The NBS said that investment in the nation's property sector has maintained strong growth by rising 34.6 percent year-on-year to reach 1.87 trillion yuan (8.6 billion) in the January-May period, which might have been a result of affordable housing investment.Figures from the NBS also reflected that property developers are getting less funding from banks, as the government continued to raise borrowing costs for developers and tighten liquidity in the market.Developers obtained 580.3 billion yuan from domestic loans in the first five months, up 4.6 percent year-on-year. Meanwhile, they used 26.6 billion yuan of foreign investment in the sector, posting a year-on-year rise of 57.3 percent.

  

WASHINGTON, Aug. 2 (Xinhua) -- The weakness of aging is associated with leaky calcium channels inside muscle cells and a drug already in Phase II clinical trials for the treatment of heart failure might plug those leaks, according to a report published Tuesday in the online edition of Cell Metabolism.Earlier studies by the research team led by Andrew Marks of Columbia University showed the same leaks underlie the weakness and fatigue that come with heart failure and Duchenne muscular dystrophy."It's interesting, normal people essentially acquire a form of muscular dystrophy with age," Marks said. "The basis for muscle weakness is the same." Extreme exercise like that done by marathon runners also springs the same sort of leaks, he added, but in that case damaged muscles return to normal after a few days of rest. A microscopic view shows smooth muscle cells derived from human embryonic stem cells showing the nuclei (blue) and proteins of the cytoskeleton (green) in this handout photo released to Reuters by the California Institute for Regenerative Medicine, March 9, 2009The leaks occur in a calcium release channel called ryanodine receptor 1 (RyR1) that is required for muscles to contract. Under conditions of stress, those channels are chemically modified and lose a stabilizing subunit known as calstabin1.Calcium inside of muscle cells is usually kept contained. When it is allowed to leak out into the cell that calcium itself is toxic, turning on an enzyme that chews up muscle cells. Once the leak starts, it's a vicious cycle. The calcium leak raises levels of damaging reactive oxygen species, which oxidize RyR1 and worsen the leak.The researchers made their discovery by studying the skeletal muscles of young and old mice. They also showed that 6-month-old mice carrying a mutation that made their RyR1 channels leaky showed the same muscular defects and weakness characteristic of older mice.When older mice were treated with a drug known as S107, the calcium leak in their muscles slowed and the animals voluntarily showed about a 50 percent increase in the amount of time spent wheel running. Now in clinical trials for patients with heart failure, the drug is known to work by restoring the connection between costabilin and RyR1.Despite considerable effort to understand and reverse age- related muscle wasting, there are no established treatments available. The new work suggests there may be hope in approaching the problem from a different angle."Most research has focused on making more muscle mass," Marks said. "What's different here is that we are focused not on muscle mass but on muscle function. More muscle doesn't help if it is not functional."

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