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Quibi, a streaming service specializing in short-length videos, is reportedly shutting down, according to multiple reports.The Wall Street Journal first reported the news Wednesday morning, citing people familiar with the matter. They explain the service had trouble nearly from the moment it launched in April, facing low viewership and low download numbers during a global pandemic.Quibi was once seen as having a lot of potential, raising .75 billion in capital. It focused on mobile devices and short-length videos.Jeffrey Katzenberg, one of the founders of the company, is a former Disney executive who started DreamWorks, and helped raise that money for Quibi by partnering with most of the major Hollywood studios, Google, Alibab, among others, according to The Information.Meg Whitman was Quibi’s CEO.No word on what will happen to the content reportedly under production for Quibi. 900

Reservations will be required on Amtrak's Pacific Surfliner route during the Thanksgiving holiday period to safely manage the increase of travelers and control the spread of COVID-19.The company announced Thursday that a reservation will be required on trains that travel between San Diego, Orange, Los Angeles, Ventura, Santa Barbara, and San Luis Obispo counties beginning Monday, Nov. 23 through Nov. 30 to help manage the capacity and allow customers to socially distance.Additionally, the Rail 2 Rail program will be suspended during this period, and monthly Metrolink and COASTER passes will not be accepted onboard Pacific Surfliner trains on these dates.Amtrak monthly and 10-ride passes may still be used. However, multi-ride ticket holders will be required to confirm each trip through the Amtrak RideReserve program on Amtrak.com, the Amtrak app, or with an Amtrak agent before traveling.Additional cars are being added when possible to increase the number of available seats on select trains.Visit pacificsurfliner.com for additional information on booking and safety precautions. 1100

Reporters are pressing McConnell to discuss the presidential election/the President’s allegations, but McConnell keeps saying he has already said what he wanted to say. I asked: if Joe Biden wins, will there be a peaceful transfer of power? He did answer that one. @LEX18News pic.twitter.com/DQ3KTyHeq0— Karolina Buczek (@Karolina_Buczek) November 6, 2020 363

President Donald Trump's niece offers a devastating portrayal of her uncle in a new book. Mary Trump writes that a “perfect storm of catastrophes” have exposed the president at his worst. Early copies of the book, “Too Much and Never Enough: How My Family Created the World’s Most Dangerous Man," slated for publication next week, became available on Tuesday.She writes that the coronavirus pandemic, the possibility of an economic depression and deepening social divides have brought out the “worst effects" of Trump's "pathologies." Multiple media outlets, including CNN and the New York Times, are reporting on details from the book, including that Mary Trump alleges President Trump paid to have someone take the SAT for him. She says the combination of emergencies are problems that “no one is less equipped than my uncle to manage." Mary Trump is the daughter of Trump's eldest brother Fred Trump Jr., who died in 1981. Trump's other brother Robert, filed injunctions to stop the publication of the book. Robert Trump's lawyers argued Mary Trump had agreed not to publish such a book without permission from the family. Last week, a New York court ruled the book could be released. 1196

Researchers published what they say is the first case of a living person diagnosed with the degenerative brain disease chronic traumatic encephalopathy or CTE.While unnamed in the study, lead author Dr. Bennet Omalu confirmed to CNN that the subject of the case was former NFL player Fred McNeill -- who died in 2015.Omalu is credited with first discovering CTE in professional football players. Until now, the only way to diagnose the disease is with a brain exam after death.The diagnosis was first made using an experimental brain scan that can trace a signature protein of CTE called tau. The authors then confirmed the diagnosis with an autopsy. The case study was published in the journal Neurosurgery this week.'It looked like just depression'Omalu first presented these findings exclusively to CNN's chief medical correspondent, Dr. Sanjay Gupta, in 2016. McNeill's wife, Tia, and his two sons, Gavin and Fred Jr., told Gupta then that they saw Fred transform from a fun loving family man at the center of their lives into a man who was dealing with symptoms of memory loss, anger and depression that tore their family apart."There are some times where the father is the stronghold in the family, or the anchor. If you lose that, everything kind of falls apart. That's kind of what happened for us. It looked like financial issues at first; it looked like marital issues, and they separated; then it looked like just depression," Gavin told Gupta.CTE is known for plaguing people with Alzheimer's like symptoms such as memory loss, rage, mood swings, and in some cases, suicidal ideation.Severity of the disease is categorized into four stages, with stage 4 being the most severe. While researchers don't know exactly why certain people develop the disease and others don't, they believe that it results from repeated blows to the head that trigger a build up of tau proteins in the brain.CTE has been called football's "concussion crisis," however experts point out that CTE can develop from any repeated head injury. According to the Boston University CTE Center, "this trauma includes both concussions that cause symptoms and subconcussive hits to the head that cause no symptoms." These subconcussive hits can include the repeated trauma the brain experiences from constant plays, hitting the turf, and tackling. Wrestlers, boxers, and military troops have also been diagnosed with the disease.Seeing CTEWhile McNeill is the first case to be confirmed with an autopsy, the experimental technology has been used on at least a dozen other former NFL players, including Pro Football Hall of Famer, Dallas Cowboy Tony Dorsett. Omalu helped develop and is invested in the diagnostic exam, which uses a radioactive "tracer" called FDDNP to bind to tau proteins in the brain. The tau proteins can then be seen on a PET scan of the brain.Critics have said the protein also can highlight another protein called amyloid, which may be indicative of Alzheimer's or other forms of dementia. But Omalu noted that in CTE, tau makes distinctive patterns in the brain. It has a "specific topographic signature," he said, and that pattern can be detected in imaging.Omalu said he and his team are currently raising money to start a phase 3 clinical trial to further test the technology and replicate what they have seen in McNeill. He anticipates that once funds are raised, it will take another two to three years for the trial and then another year, at least, for approval from the US Food and Drug Administration. When asked, how soon a commercial test could be available, Omalu predicted it could be as soon as a few years. "We are looking at less than five years," he said.  3711