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CHICAGO, Ill. – Scientists have identified nearly 70 drugs that could be effective in treating the coronavirus. But already, some drugs are being improperly prescribed or hoarded even before they can be adequately investigated and tested. For some who rely on the life-saving drugs for other ailments, shortages are already being felt. Across the country, some people with chronic illnesses are finding their much-needed medications are on backorder. One drug in short supply is Plaquenil, generically known as hydroxychloroquine sulfate. It’s used to treat malaria and chronic rheumatic diseases. “It prevents them from having severe pain, from their symptoms getting worse, from forming modules. This is a daily medication that these people absolutely need,” said Erin Fox, who’s with the American Society of Health-System Pharmacists. Fox, who maintains a list of nationwide drug shortages, says four of the eight producers of hydroxychloroquine are running out. “We’ve definitely seen a rapid increase in demand for this product,” she said. “I think it’s a frustrating problem and I think it’s really scary for those patients that rely on this medication day in and day out.” While hydroxychloroquine is not FDA-approved as an off-label treatment option for novel coronavirus, it has already been touted by the president as a potential game-changer. “Millions of units are ordered, and we’re going to see what happens,” said President Donald Trump. “We’re going to be talking to the governors about it, and the FDA is working on it right now.” Last week, a French study of just 20 people reported 70% of coronavirus patients treated with Plaquenil after six days tested negative for the virus, compared to 12.5% of the control group. Hospitals across the country are stockpiling it as a precaution. The state of New York has already acquired 70,000 doses as part of its own drug trials this week. But with no large-scale clinical data available, public health officials warn it’s too early to know whether the drug is effective against coronavirus. When asked about hydroxychloroquine’s efficacy at a White House coronavirus task force brief late last week, Dr. Anthony Fauci, Director of the National Institute of Allergy and Infectious Diseases, said more studies are needed. “The information that you’re referring to specifically is anecdotal; it was not done in a controlled clinical trial,” said Fauci. “So, you really can’t make any definitive statement about it.” Dr. Jessica Nouhavandi, the lead pharmacist and CEO of L.A.-based online pharmacy 2574
It’s hard to know exactly what your symptoms mean, especially these days.“In actuality, the differences are really very small and almost negligible,” said Cleveland Clinic Dr. Baruch Fertel.According to Fertel, there are little differences between COVID and flu symptoms.“The muscle aches, the fever, the cough, GI symptoms like diarrhea, headache those symptoms can be found with both,” said the doctor.But there is one difference."I would say the only major difference, which is actually a minor difference is that loss of taste or smell that’s something that seems to be unique to the COVID-19 coronavirus and not something we’ve seen in the past with the flu,” said Fertel.He says this flu season will be much different from others."I think in the past, I certainly made an empiric diagnosis of the flu, I told people to stay home, stay out of work for a couple days, no problem,” said Fertel. "I think it's really important to get testing for a number of reasons, the isolation period for COVID is longer than that of the flu. The infectivity of COVID is more than that of the flu and understating for contract tracing and other such public health measures what.”He’s encouraging folks to get a flu shot this time, even if you haven’t in the past."If we could prevent that and have less fibril illnesses because people have gotten the flu shot, it will just make it that much easier to deal with schools, work, things like that and prevent so much disruption,” said the doctor.Fertel adds because we’re already doing things that help slow the spread of a viral infection, this all could help this flu season be less deadly."When people pay attention when they wash their hands whatever measures we put in place to stop the spread of coronavirus will absolutely work as well for the flu,” he said.This story originally reported by Amanda VanAllen on News5Cleveland.com. 1894
Once a week, Karelia Lanuza comes by Viola Zilio's apartment to help her with whatever she might need, whether it’s finishing a puzzle, helping with chores or reminding her to take her medications. The two will often run errands or go for walks. Often times, they’ll even stop at Zilio’s favorite café to get the traditional Cuban coffee. Lanuza isn’t a traditional caregiver. She more of a companion, according to Zilio. The pair met when Lanuza signed up to work for Papa, a new app and phone-based service for seniors. "Papa connects college students to older adults for companionship, assistance, and transportation,” says CEO and founder Andrew Parker. “It’s kind of like a grandkid on-demand." Parker thought pairing college students with seniors could fill a void he saw. “My grandfather, who we call papa, needed help but wasn't really ready for traditional healthcare services, and I thought it was weird there was nothing available before that,” Parker says. “So, I thought it would be interesting to connect him to college student, and he loved it.” Lanuza is a sophomore pre-med student, and she needed a job that fit with her busy class schedule. She passed the company's background and personality checks and got the gig. “I came over. I met Viola and we clicked instantly,” Lanuza says. “And from there, I’ve been coming every Tuesday to see her, and we hang out. It’s just like hanging out with a friend.” Zilio says Lanuza gives her someone to talk to. "Seeing her once a week is kind of like being like another grandmother to me,” Lanuza says.Currently in the Miami area, Papa costs around an hour. The service is only operating across Florida right now, but the company says they have plans to expand to several more cities nationwide soon. 1777
In New York City, it easy to hear the present. But to hear the past, you’ll have to step into Rick Kelly’s shop. “Just celebrated 50 years of guitar making,” Kelly says. “1968. I started that. Was the first one I made in high school.” What sets Kelly’s craft apart from other guitar makers is the material he uses.“If you start with really old materials, you're going to have a better instrument,” he explains. The pieces were once part of the deep roots of Manhattan. “Using New York City wood from these old buildings,” Kelly says. “I call it the bones of old New York, because it's the bones of these old buildings from the 1800's down here.” The guitars are handmade of hand-picked scraps of old pine. “We actually have the largest depository of old pine in the world right here in New York City,” Kelly says.All of the building bones is transformed into detailed pieces of playable art. “You can kind of just smell the history back here,” says customer Kelly Wilson. 985
CANARY ISLANDS -- Imagine rowing almost non-stop across the Atlantic Ocean with a group of four people. No bathroom, no shade and a limited supply of food. “You’re totally exposed to the elements,” said Evan Stratton, a U.S. veteran. Evan and three others rowed across the Atlantic Ocean from the Canary Islands off of Spain to Antigua, near Puerto Rico, as part of the Talker Whiskey Atlantic Challenge — a yearly ocean rowing race. The path is 3,000 nautical miles. “Our row took 50 days, 11 hours, and 35 minutes,” he said. “Which seems like a really long time, but we actually set a world record for our boat class.” The team, titled Fight Oar Die, was the only American team to compete this year. More than just a physical challenge, the race is a test of the mind as well. We sat down with Evan, who walked us through it. “It’s really a challenge in mental strength,” he said. “It’s an introspective look at yourself whether you want one or not because you remove all inputs,” he explained. “There’s no work phone calls, no e-mails, no TV, no radio.” Through their journey, psychologists are hoping to learn something. “We got involved as part of that research component,” said Dr. Trey Cole, a clinical psychologist and former veteran himself. Dr. Cole oversees the researchers from the University of Denver that have been working with the Fight Oar Die rowing team throughout their experience. “There’s a lot to do with motivation and sleep and purpose and those type of factors we’re trying to take a closer look at,” Dr. Cole said. He helped the men prepare beforehand too — with conflict resolution, stress management, and other skills. “It’s hilarious to be sitting in your off shift in the cabin hearing two guys on the boat yell at each other but they’re still just rowing,” Evan said. “The end goal is you gotta get there.” It was a team effort with personal mental challenges each rower dealt with individually. Part of Evan’s way of getting through was the photos and cards his wife packed for him, cards he could open when he hit “the wall,” when he was “almost home,” and on his son’s first birthday that he missed while rowing. Evan said a challenge like this took the support of his family, but it all starts with motivation. “It just takes getting out and doing it,” he said.Evan spent four years of his life as a Marine earlier on in his life. “I went through my own battles with PTSD and mental health,” he said. Bringing awareness to mental health was part of his motivation for joining the rowing team this year. “We really wanted to show veterans that life doesn’t end after the military, that you can still go out and do really big things and really hard things and really incredible things,” Evan said. This awareness is at the forefront of Fight Oar Die’s mission — to provide a platform for veterans' mental health issues.“The hope is that we can generate some conclusions from that that could be helpful in informing the future of veteran and service member care,” Dr. Cole said. Cole and other researchers will continue to look into the data from the rowing teams each year. 3122