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发布时间: 2025-05-30 11:11:46北京青年报社官方账号
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The United Kingdom says it will be the first to conduct COVID-19 vaccine human challenge trials.It's different than other vaccine studies. People will be deliberately infected with the virus, which speeds up the research process.Pending approval, the process will start in January at a London hospital. It will require about 90 healthy young adults between the ages of 18 and 30.The group 1 Day Sooner has recruited from all over the world, including 3,000 Britons.“If the vaccine works, then ideally, people don't get infected and if people do, then they will be closely monitored and treated, but because these are young and healthy people taking part in the trial, I think, researchers feel comfortable doing so because the risks of death are on par with something like kidney donation for people who are young and healthy,” said Abie Rohrig with 1 Day Sooner.Before researchers test the vaccine, they'll do a characterization study. That's where volunteers are infected by getting a vaccine to determine the right amount of virus to give during the trial.Because of the risk, 1 Day Sooner is advocating for the entire process to be made public.Results could come in May. Even though that's likely after other COVID-19 vaccines are licensed, it's still important because we need billions of doses and because of the unique data human challenge trials provide.“Researchers can understand how the virus works in the human body. They can understand the biological markers of immunity. In fact, much of our understanding of other types of coronaviruses come from challenge studies that were conducted in the 1960s in Britain,” said Rohrig.Human challenge volunteers are paid and monitored for at least a year after. 1722

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The Vans Warped Tour, a long-running punk rock tour and festival that pushed the genre into national relevance, will end after 2018.Warped Tour founder Kevin Lyman shared the news on the tour's website, in an essay headlined "All Good Things Must Come to an End.""It will be bittersweet each morning when I see the sun rise and then watch it set knowing that this will be the last time I get to witness it from that exact spot," Lyman wrote. "Though the tour and the world have changed since ’95, the same feeling of having the ‘best summer ever’ will live on through the bands, the production teams, and the fans that come through at every stop."The Warped Tour has been a summer staple in American cities since 1995. Each year, festival tour featured dozens of acts and multiple stages throughout cities in North America. Acts like Fall Out Boy, Blink-182, The Offspring, Simple Plan and Sum 41 got their start on the tour and helped start a pop punk revolution in the late '90s and early 2000sThough Lyman said the 2018 tour would be the festival's last, he also wrote that he is currently preparing a 25th anniversary celebration for the first Warped Tour in 2019.The cities and dates of the final Warped Tour are listed below. 1259

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The state of Oregon became the first in the nation to decriminalize small amounts of hard drugs like heroin and cocaine by overwhelmingly passing Measure 110 on Tuesday.According to The Oregonian, the measure will reduce misdemeanor drug possession to a non-criminal violation, punishable by measures similar to a traffic stop. Violators will be given a ticket and a 0 fine, or be given the option of being screened for a subtance abuse disorder.Those found with larger amounts of drugs, who would have previously been charged with a felony, will now face a misdemeanor charge. The measure also redirects tax revenue from the sale of legal marijuana in the state toward Addiction Recover Centers, where people are screened for drug use and can also receive treatment for drug addiction.Supporters of the measure say the new policy will reduce the state's jail population, and in particular, free many offenders of non-violent crimes. Supporters also say the bill will promote racial equality in the state, as drug laws disproportionately affect Black people and other people of color.Opponents of the measure say it promotes drug use and will lead to more overdose deaths and overwhelm addiction centers in the state.The Oregonian also reports that the measure received funding from many out-of-state donors, including Facebook founder and CEO Mark Zuckerberg.The Associated Press reports that the measure passed with about 60% support.In addition to decriminalizing hard drug use, Oregon also legalized the sale and recreational use of Psilocybin, or magic mushrooms. The Associated Press reports that the measure passed with 56% support. 1650

  

The SAT college entrance exam given to thousands of high school students across the United States may have been leaked in Asia ahead of Saturday's test, the Los Angeles Times reported.High school junior Huzail Hassan of Rancho Cucamonga received a text from a friend who said the College Board, which administers the exam, reused a test from last fall, the LA Times reported.“I checked on Twitter and so many people had taken screenshots,” Hassan told the LA Times. “I looked it up and it was the same exam. It had the exact same questions and it had the answer key.”RELATED: San Diego teachers, students call for free in-school SAT testingScripps station KGTV in San Diego received a statement from the College Board addressing the next steps for students."In response to theft and organized cheating, which affects all high stakes testing, we have significantly increased our test security efforts and resources. We have a comprehensive approach to test security and go to great lengths to make sure that the test scores we report are accurate and valid. In all our efforts, we’ve worked to strike a balance between thwarting those seeking an unfair advantage and providing testing opportunities for the vast majority of students who play by the rules," wrote Associate Director of Media Relations Jaslee Carayol in an email."As part of our comprehensive approach, after every test administration, we take additional quality control steps before scores are released, including conducting a comprehensive statistical analysis of certain test scores. If we determine students have gained an unfair advantage, we will take appropriate actions, including cancelling test scores and, in some cases, prohibiting them from taking another College Board assessment. To protect the security of our tests, we cannot comment on the specifics of question usage and test administration schedules."RELATED: Report of student cheating may have led to AP debacleThe SAT, or Scholastic Aptitude Test, was created in 1926 to serve as a benchmark for the academic performance of graduating students. It measures performance in mathematics and critical reading and writing. Scores range from 400 to 1600, combining the results from the two 800-point section. Students pay , or with the optional essay, to take the SAT.The test is run by the College Board, a nonprofit group with a membership of more than 6,000 educational institutions.  2463

  

The United States could see an increase in immigrants coming to the country after Hurricanes Irma and Harvey, according to new research from the University of Michigan.According to the study, there are multiple reasons this happens, including migrants might find it easier to flee destruction in their own country.Another reason, according to U-M economists Dean Yang and Parag Mahajan, is they are able to secure green cards or legal permanent residency through their families already established in the country."When there's a bigger stock of previous migrants to the U.S., when someone in their home country is more likely to have a connection to some sort of migrant in the U.S., then the effect of hurricanes on migration is larger," Yang said.The researchers first studied the severity of a hurricane in a given country, using data from meteorological reports to estimate actual damage.Yang and Mahajan then analyzed restricted U.S. Census data from 159 counties over 25 years to see if America saw a rise in immigration following large storms in other countries.The largest effect came from Central America and the Caribbean."These regions get hit a lot by hurricanes that cause severe damage, and there are a lot of Central American and Caribbean immigrants in the U.S., so if you're looking for someone to sponsor you, you actually have that opportunity," Mahajan said.One example of that is Hurricane Cesar hitting Nicaragua in 1996. It caused food shortages, .5 million in damage, left 100,000 people homeless and killed 42. Yang and Mahajan found that in 1996 and 1997, there was a 50 percent increase in legal permanent residencies for Nicaraguans than in 1995."Much of this increase came from immediate relatives of U.S. citizens - parents, spouses and children," Mahajan added. "Repeated, similar responses like this in the data helped us conclude that networks of U.S. citizens from sending countries provide opportunities for family members to escape severe weather events." 2007

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