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BEIJING, Feb. 8 (Xinhuanet) -- China's railroads and highways will see their busiest day of the Spring Festival holiday on Tuesday when the number of travelers returning to major cities hits its peak, just as a cold snap sweeps across much of the country, the ministries of railways and transport said on Monday.The Ministry of Railways said on its website that there had been a sharp rise in the number of travelers leaving smaller cities on Monday bound for such places as Beijing, Shanghai and Guangzhou.The ministry said the number of people on the move on Tuesday is likely to make the day the Spring Festival travel peak.The nation's roads are also likely to be at their Spring Festival maximum on Tuesday and Wednesday, the Ministry of Transport reported on Monday on its official website.The National Meteorological Center (NMC) added on Monday that a moderate cold snap was expected on Tuesday, causing temperatures to fall by between four and six degrees in most parts of China.The weather pattern will bring widespread rain and snow to the southern part of China from Wednesday to Friday, the NMC said.The Ministry of Railways said on its website that it has asked its local branches to be prepared for the upcoming icy weather.Meanwhile, the local authorities in big cities have been bracing for the arrival of massive numbers of travelers as the Spring Festival holiday winds down.In Shanghai, tens of thousands of public transportation workers cut their holidays short and put 27 additional bus lines on the road to meet demand as passengers began arriving in large numbers at the city's railway stations.The influx began on Saturday night, according to local newspaper Wenhui Daily.On Sunday, the pressure intensified on the Qinghai-Tibet railway, two days earlier than expected.As a result, the railway company organized additional workers to facilitate the flow of people through Xining Railway Station in Northwest China's Qinghai province.Many volunteers have also been pitching in to help keep people moving and have offered to do various jobs at stations, such as helping people buy tickets and assisting them in checking their travel schedules.Among them, Liu Chen, a student from the Guangzhou-based Zhongkai University of Agriculture and Engineering, has been helping people at Guangzhou Railway Station by carrying their bags."One day, I helped more than 70 passengers with their luggage and, after all of them got on the trains, it felt like my legs were almost paralyzed," he said.The Hohhot railway bureau in North China's Inner Mongolia autonomous region said it is expecting so many extra passengers that it has scheduled four additional trains for lines to Chongqing and Beijing.With so many people scrambling to get back from family gatherings and holidays to their jobs in China's big cities, the rush to buy tickets has been phenomenal. Tickets for trains that will leave Nanjing on Tuesday for Beijing, Guangzhou, Harbin and Changchun had virtually all gone on Monday morning, Jiangsu's Yangtse Evening Post reported.On Sunday, the fourth day of Spring Festival, the country's railways carried a total of 5.3 million travelers, which was up by 12.8 percent on the 4.7 million who rode the rails a day earlier, according to the Ministry of Railways.Another 38.6 million travelers made Spring Festival trips on Sunday on buses and ships, according to the Ministry of Transport.The traditional chunyun period, or Spring Festival travel season, runs for 40 days and is calculated in two phases: 15 days before Spring Festival Eve and 25 days after it, as stipulated by the central government.China's railways moved about 77.3 million passengers during the first 15-day period, which ran from Jan 19 to Feb 2, the Ministry of Railways reported.

IWATE, Japan, March 14 (Xinhua) -- A 15-strong Chinese international search and rescue team Monday morning set out to join the relief work in Oofunato, Iwate, a city severely damaged by a 9.0-magnitude earthquake Friday.The Chinese international search and rescue team, which arrived in Oofunato at around 10:30 p.m. Sunday night, is the first overseas team to join and help out the relief work in the city.Team leader Yin Guangfui said they have brought along life exploration device and some other equipment to help carrying out the rescue.The team, with good experience in search and rescue, will strive to do the relief work, Yin added.The team members, including rescue and medical personnel, gathered at a primary school in Oofunato on Sunday and set off at 7:30 a.m. to the disaster-hit area together with the Japanese rescue teams after a briefing. The team is expected to be here for seven to 10 days.The catastrophic earthquake hit northeast of Japan on March 11, triggering severe tsunami and causing extensive damage and loss in different areas. According to local media, a total of 985 people have been confirmed dead, 707 others injured and over 1,700 others missing.

LUQA, Malta, Feb. 28 (Xinhua) -- Four chartered planes of China Eastern Airlines left Malta Monday, taking home 1,115 Chinese nationals evacuated from Libya. The forth Airbus A340 plane with 275 evacuees on board took off from the Malta International Airport at about 08:40 p.m. local time (1940GMT), bringing the total number of Chinese nationals back home from Malta to 2,223.The flight CES 266 with 275 Chinese nationals on board flew to Beijing while the other three will land in Shanghai, according to Chinese Embassy in Malta.Three chartered flights are expected on Tuesday, the embassy said.In the past 48 hours, three chartered cruise ship with 4,800 Chinese evacuees have reached Valletta, capital of Malta.

WASHINGTON, April 25 (Xinhua) -- A class of drugs that shows promise in breast and ovarian cancers with BRCA gene mutations could potentially benefit colorectal cancer patients with a different genetic mutation, a new study from the University of Michigan Comprehensive Cancer Center finds.Working in cell lines from colorectal cancer patients, researchers found that the class of drugs called PARP inhibitors worked against tumors with mutations in the MRE11 gene.About 15 percent of all colorectal cancers have what's called microsatellite instability, a type of error in the DNA. About 82 percent of those tumors have the MRE11 gene mutation."This is a potential broader application for PARP inhibitors, beyond breast and ovarian cancer. This is a class of drug that's already shown safety in early clinical trials and now might benefit some colorectal cancer patients as well," says lead study author Eduardo Vilar-Sanchez, a hematology/oncology fellow at the university, in a statement.The study, which was published Monday in Cancer Research, also found that PARP inhibitors are even more effective when both copies of MRE11 were mutated. Each person carries two copies of each gene, which means mutations can occur in either one or both copies. The researchers suggest that PARP inhibitors could be targeted specifically to colorectal cancer patients who have two copies of the mutated gene.Researchers are planning a phase I clinical trial to look at using PARP inhibitors in colorectal cancer patients with two mutated copies of MRE11. Future trials are being considered using PARP inhibitors to prevent colorectal cancer and other cancers in people with Lynch syndrome whose tumors have this mutation.Microsatellite instability is also seen in prostate cancer and endometrial cancer, suggesting potential for PARP inhibitors to play a role in additional types of cancer as well, Vilar-Sanchez says, adding that more research is needed in these areas.