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Excessively high or low body mass index measurements have been linked to an increased risk of dying from nearly every major cause except transport accidents, new research says.The?study, published Wednesday in The Lancet Diabetes and Endocrinology and conducted by scientists at London School of Hygiene and Tropical Medicine, revealed that BMI that's either too high or too low is tied to increased morbidity from a range of major diseases.Krishnan Bhaskaran, lead author of the study and associate professor of statistical epidemiology, noted that his team found "important associations" between BMI and most causes of death."BMI is a key indicator of health. We know that BMI is linked to the risk of dying overall, but surprisingly little research has been conducted on the links to deaths from specific causes," he said."We have filled this knowledge gap to help researchers, patients and doctors better understand how underweight and excess weight might be associated with diseases such as cancer, respiratory disease and liver disease."BMI is determined by dividing a person's weight in kilograms by the square of their height in meters.The study authors say they discovered that maintaining a BMI in the range of 21 to 25 kg/m2 is linked to the lowest level of morbidity.BMI outside this range was shown to have a "J-shaped association" with nearly all causes of death, not solely the most prevalent diseases. This means BMIs both lower and higher than the optimal range lead to increased risk of morbidity.The study, which analyzed data from 3.6 million people and 367,512 deaths, showed that obesity, or BMI of 30 or more, was linked to an increased prevalence of two major causes of death: heart disease and cancer."BMI higher than 25, the upper end of healthy, is linked to most cancers, most cardiovascular diseases, respiratory disease, and liver and kidney conditions," Bhaskaran said.Obesity was shown to reduce life expectancy by 4.2 years in men and 3.5 years in women, and it can contribute to other chronic conditions including respiratory disease, liver disease and diabetes.The British Journal of Cancer reported in April that obesity is linked to 7.5% of cancers in UK women.The charity Cancer Research UK estimated that 23,000 women will deal with obesity-related cancers by 2035. Obesity will also become the most common cause of cancer in women by 2043 if trends continue.The study also revealed that being underweight is linked to a "surprising wide range of deaths," including dementia, Alzheimer's, cardiovascular disease and suicide.However, Bhaskaran noted that links between low BMI and causes of death were more "observative," as it was less clear whether low weight was the direct cause of illness or rather a marker of poor health more generally.He also acknowledged the limitations of the study, which included a lack of information on the diet or level of physical activity of the individuals involved and the impact these factors may have had on morbidity.He nevertheless noted that the findings reiterated the importance of maintaining a BMI within the 21 to 25 range. 3130

FALLBROOK (KGTV) - A mobile home fire spread to brush in the Fallbrook area, North County Fire reported Tuesday.The flames broke out about 2:40 p.m. at Highway 395 and Rainbow Valley Road. The mobile home fire sparked three small brush fires nearby.The fires were extinguished within half an hour.There are no reports of injuries or road closures.An employee of a nearby business was unaware of the fire.10News is monitoring breaking developments. 455

FALLBROOK (KGTV) - One person is dead after she was hit by a vehicle while walking along the shoulder of a road in Fallbrook with her husband.CHP officers say the 60-year-old woman was walking with her husband just after 5 p.m. northbound on the east shoulder in the 2700 block of Gird Road north of Laketree Drive. An approaching pickup truck heading northbound left the roadway and struck the woman. The truck stopped for a moment before fleeing the scene northbound on Gird Rd.North County Fire Protection District and CHP responded and crews began life saving measures at the scene, but the woman was pronounced dead. Her 60-year-old husband was not injured.The truck involved in the crash is described as an older model pickup truck that's dark in color. The truck will likely have damage to the right front side.Investigators were reviewing surveillance footage from the area to learn more about what happened.Anyone with information on the whereabouts of the suspected vehicle or information about the crash is asked to call CHP at 858-637-3800. 1060

ESPN is expected to cut at least another 100 employees after Thanksgiving, marking the company's third round of layoffs in the last three years, Sports Illustrated reported on Thursday. According to SI, the layoffs are expected to include several anchors from ESPN's longest-running program "SportsCenter." The layoffs are also expected to include other employees such as producers, executives and other staffers, SI reported. The layoffs to end 2017 come just seven months after ESPN laid off nearly 100 reporters from its roster. Among those laid off were basketball reporter Andy Katz, baseball reporter Jayson Stark and SportsCenter anchor Jay Crawford, to name a few. In 2015, ESPN laid off 300 employees, most of whom were behind the scenes staff. In recent years, ESPN has had to combat rising fees to carry live sports, coupled with a decline in cable television subscriptions. According to eMarketer, nearly 22 million former cable subscribers have "cut the cord" in recent years.   1034

Ensa Cosby, daughter of embattled comedian Bill Cosby, has died at the age of 44, TMZ reported and the Associated Press confirmed on Monday. Ensa Cosby reportedly died Friday night in Massachusetts. The cause of her death is unknown as of Monday afternoon. Ensa Cosby was a steadfast supporter of her father, who has been battling accusations of sexual misconduct. Bill Cosby faced a sexual assault trial in 2017, which ended in a mistrial. Ensa Cosby issued a statement on last year on "The Breakfast Club" radio show backing her father. "The accusations against my father have been one-sided from the beginning. When he tried to defend himself, he was sued in civil court," she said. "I've seen the accusations become more horrific and extreme with time and I've witnessed my father's reputation and legendary works be dismissed without any proof."I strongly believe my father is innocent of the crimes that are alleged against him and I believe that racism has played a big role in all aspects of this scandal. How the charges came against him, how people believed them before they were ever scrutinized or tested, how people who questioned the claims were shut down and ignored."Ensa Cosby did not follow her father into show business. Her only acting credit came in 1989, appearing in one episode of "The Cosby Show."Ensa is the second of Bill Cosby's five children to have died. In 1997, Cosby's son Ennis died during an armed robbery.  1510