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U.S. government officials are putting an early end to a study testing an Eli Lilly antibody drug for people hospitalized with COVID-19 because it doesn’t seem to be helping them.Independent monitors had paused enrollment in the study two weeks ago because of a possible safety issue. But on Monday, the National Institute of Allergy and Infectious Diseases, which sponsors the study, said a closer look did not verify a safety problem but found a low chance that the drug would prove helpful for hospitalized patients.It is a setback for one of the most promising treatment approaches for COVID-19. President Donald Trump received a similar experimental, two-antibody drug from Regeneron Pharmaceuticals Inc. on an emergency basis when he was sickened with the coronavirus earlier this month.In a statement Lilly notes that the government is continuing a separate study testing the antibody drug in mild to moderately ill patients, to try to prevent hospitalization and severe illness. The company also is continuing its own studies testing the drug, which is being developed with the Canadian company AbCellera.Antibodies are proteins the body makes when an infection occurs; they attach to a virus and help it be eliminated. The experimental drugs are concentrated versions of one or two specific antibodies that worked best against the coronavirus in lab and animal tests.Lilly and Regeneron have asked the U.S. Food and Drug Administration to grant emergency use authorization for their drugs for COVID-19 while late-stage studies continue. Lilly says its request is based on other results suggesting the drug helps patients who are not hospitalized, and that it will continue to seek the FDA’s permission for emergency use.___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 1928

Tropical Storm #Wilfred Advisory 1: Wilfred Forms in the Eastern Tropical Atlantic. Get Out the Greek Alphabet For the Rest of 2020. https://t.co/VqHn0u1vgc— National Hurricane Center (@NHC_Atlantic) September 18, 2020 226

UPDATE (10:23 a.m.): San Diego Sheriff's Department says Cannon returned safely to his residence at about 9:30 a.m. Saturday.LAKESIDE, Calif. (KGTV) — An East County diagnosed with early dementia disappeared from his home late Friday, sheriff's deputies say.William Cannon, 84, was last seen Friday at about 9 p.m. driving away from his home in a white Toyota Prius. According to Cannon's son, he has been diagnosed with early stages of dementia.Cannon is described as a Caucasian male, standing about 5-foot 10-inches, weighing 150 pounds, with grey hair, and blue eyes. He was last seen wearing a black baseball hat with the letters "SR71", a beige or white windbreaker jacket, blue jeans, and tennis shoes.His Toyota has the California license plate 7TJT465.Anyone with information is asked to call the San Diego Sheriff's Department at 858-565-5200. 861

Unions representing about 35,000 Disney World workers say Disney is refusing to pay their members ,000 tax cut bonuses.Disney announced the ,000 bonuses last month for 125,000 U.S. employees. The company said at that time that the bonuses would go to full and part-time employees, including those represented by unions "currently working under existing union contracts."But the union members at Disney World are in the midst of contract negotiations. They say rank-and-file workers in December voted 93% against Disney's most recent offer of a 50-cent-an-hour raise over the next two years, coupled with a 0 signing bonus. Most unionized Disney World employees make less than an hour, according to the union.Only 3,000 make more than an hour. The union says the average hourly wage for its members is .71.Eric Clinton, president of the Unite Here local at the theme park, said Disney is forcing the union to accept that same rejected offer for its members to receive the ,000 bonus due to other Disney employees."In other words Disney said you can have ,000 if you agree to stay poor," he said in a video statement posted on the union's Facebook page. "Disney is discriminating against us for having a union locked in negotiations. Let us be clear, Disney cast members deserve a living wage. We will not allow a ,000 trick of a bonus to be held over our heads."He said the union has filed an unfair labor practice complaint alleging that the demand amounts to punishing members for engaging in legally protected contract negotiations.Disney was not immediately available for comment on the union's statement, but a spokesperson told the Orlando Sentinel, "Wages and bonuses are part of our negotiation process. We will continue to meet with the union to move toward a ratified agreement."Several union members appeared in the same video denouncing the demand from Disney."This company seems to think they can trick us into taking this ,000," said union member R.J. Green. "This bonus is a short-term solution to long-term problems. There is no reason we should not be able to provide for our families."  2142

UPLAND, Calif. (AP) — The pilot of a small plane that crashed into a Southern California house and burned Thursday has died, authorities said.A father and child inside the home escaped without injuries after the late morning crash.The single-engine Cirrus SR22 went down in Upland, east of Los Angeles. Authorities believe the pilot, who was not immediately identified, was the only person aboard.Upland police Capt. Marcelo Blanco said the cause of the crash was not immediately known.TV news helicopters showed a large portion of the house gutted and smoldering. A parachute was draped over trees.Cirrus aircraft are equipped with parachutes that pilots can deploy in an emergency.The home is near Cable Airport, about 35 miles (55 kilometers) east of Los Angeles. 774