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WASHINGTON, Dec. 28 (Xinhua) -- People with diets high in several vitamins or in omega 3 fatty acids are less likely to have the brain shrinkage associated with Alzheimer's disease than people whose diets are not high in those nutrients, according to a new study published on Wednesday in the online issue of Neurology, the medical journal of the American Academy of Neurology.Those with diets high in omega 3 fatty acids and in vitamins C, D, E and the B vitamins also had higher scores on mental thinking tests than people with diets low in those nutrients. These omega 3 fatty acids and vitamin D are primarily found in fish. The B vitamins and antioxidants C and E are primarily found in fruits and vegetables.In another finding, the study showed that people with diets high in trans fats were more likely to have brain shrinkage and lower scores on the thinking and memory tests than people with diets low in trans fats. Trans fats are primarily found in packaged, fast, fried and frozen food, baked goods and margarine spreads.The study involved 104 people with an average age of 87 and very few risk factors for memory and thinking problems. Blood tests were used to determine the levels of various nutrients present in the blood of each participant. All of the participants also took tests of their memory and thinking skills. A total of 42 of the participants had MRI scans to measure their brain volume. Overall, the participants had good nutritional status, but seven percent were deficient in vitamin B12 and 25 percent were deficient in vitamin D.Study author Gene Bowman, of Oregon Health & Science University in Portland, said that the nutrient biomarkers in the blood accounted for a significant amount of the variation in both brain volume and thinking and memory scores. For the thinking and memory scores, the nutrient biomarkers accounted for 17 percent of the variation in the scores. For brain volume, the nutrient biomarkers accounted for 37 percent of the variation."These results need to be confirmed, but obviously it is very exciting to think that people could potentially stop their brains from shrinking and keep them sharp by adjusting their diet," Bowman said.

BEIJING, Nov. 9 (Xinhuanet) -- Routine bowel screening can cut deaths from bowel cancer by 27 percent, a latest Scottish study finds.The result was presented at the National Cancer Research Institute's (NCRI) conference in Liverpool. Funded by the Scottish government's health department, the study involved over 370,000 people aged 50 to 69 from Scotland. Every participant was given a FOBt (faecal occult blood test) kit-- which was used to collect their stool samples-- every two years between 2000 and 2007. The samples were sent to a laboratory for hidden traces of blood test.Under the monitor of the researchers, the participants saw a 27 percent fewer bowel cancer deaths than a similar number of people from Scotland uninvolved in the trial."For the first time, we can see the effects of an FOBt-based colorectal cancer screening program in the real world of the NHS," cheered author Robert Steele from the Bowel Screening Research Centre in Dundee.According to a BBC report, when bowel cancer is detected at the earliest stage, 90% of patients survive for at least five years. After the disease has spread, the survival rate is just 6%.

WASHINGTON, Jan. 2 (Xinhua) -- A hormone derived from visceral fat called adiponectin may play a role as a risk factor for development of all-cause dementia and Alzheimer's disease (AD) in women, according to a study published on Monday in online issue of the Archives of Neurology.Thomas van Himbergen, from Human Nutrition Research Center on Aging at Tufts University, and colleagues measured levels of glucose, insulin, and glycated albumin, as well as C reactive protein, lipoprotein associated phospholipase A2, and adiponectin in the plasma of patients at the 19th biennial examination (1985 -- 1988) of the Framingham Heart Study.The 840 patients (541 women, median age of 76 years) were followed-up for an average of 13 years and evaluated for signs of the development of AD and all-cause dementia. During that time, 159 patients developed dementia, including 125 cases of AD. After adjustment for other dementia risk factors (age, low plasma docosahexaenoic acid, weight change) only adiponectin in women was associated with an increased risk of all-cause dementia and AD."It is well established that insulin signaling is dysfunctional in the brains of patients with AD, and since adiponectin enhances insulin sensitivity, one would also expect beneficial actions protecting against cognitive decline," the authors write. "Our data, however, indicate that elevated adiponectin level was associated with an increased risk of dementia and AD in women."

WASHINGTON, Oct. 3 (Xinhua) -- Overweight or obesity may put children at three times greater risk for high blood pressure than those of normal weight, according to researchers from the Regenstrief Institute and Indiana University (IU) School of Medicine.Their study will appear in the November issue of Hypertension: Journal of the American Heart Association with advance online publication on Monday.More than 1,100 healthy Indiana school children were followed for nearly five years. The researchers found that when body mass index (BMI) reached or exceeded the 85th percentile for the age and gender of the child -- designated as being overweight -- the risk of high blood pressure nearly tripled. Obesity was defined as a BMI percentile higher than 95th. BMI is a measurement of body fat calculated from weight and height.Among study participants, 14 percent of overweight or obese children were pre-hypertensive or hypertensive, compared with 5 percent of normal weight children. These findings were consistent across age, gender and race.The average age at time of study enrollment was 10.2 years. Each child was assessed approximately eight times during the course of the study. All were healthy children and none were taking medication affecting blood pressure."Higher blood pressure in childhood sets the stage for high blood pressure in adulthood," said Regenstrief Institute Investigator Wanzhu Tu, professor of biostatistics at IU School of Medicine, who led the study. "Targeted interventions are needed for these children. Even small decreases in BMI could yield major health benefits."The researcher also found that leptin, a protein hormone which is involved in body weight regulation and metabolism, was positively associated with increased blood pressure in overweight and obese children.

WASHINGTON, Oct. 3 (Xinhua) -- The Rockefeller University confirmed Monday its Canadian-born cell biologist Ralph Steinman died three days before being awarded the Nobel Prize on Monday as the Nobel committee was unaware of his death at the time."Steinman passed away on September 30," the New York university said in a statement."He was diagnosed with pancreatic cancer four years ago, and his life was extended using a dendritic-cell based immunotherapy of his own design."The Nobel committee was unaware of Steinman's death when announcing this year's winners and it was unclear whether the prize would be rescinded because Nobel statutes don't allow posthumous award."The Rockefeller University is delighted that the Nobel Foundation has recognized Ralph Steinman for his seminal discoveries concerning the body's immune responses," says Rockefeller University President Marc Tessier-Lavigne."But the news is bittersweet, as we also learned this morning from Ralph's family that he passed a few days ago after a long battle with cancer. Our thoughts are with Ralph's wife, children and family.""We are all so touched that our father's many years of hard work are being recognized with a Nobel Prize," says Steinman's daughter Alexis. "He devoted his life to his work and his family, and he would be truly honored.""Ralph's research has laid the foundation for numerous discoveries in the critically important field of immunology, and it has led to innovative new approaches in how we treat cancer, infectious diseases and disorders of the immune system," Tessier-Lavigne says.Steinman, who discovered the immune system's sentinel dendritic cells, is this year's recipient of the Nobel Prize in Physiology or Medicine. He shares half the prize with Bruce Beutler and Jules Hoffmann.