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With over 160 vaccines in development, the race to defeat COVID-19 continues.A California company hopes to deliver its vaccine to your mailbox; one that is pain-free and doesn't require a needle and syringe."One of the things I wanted to do was make vaccines more patient-friendly, so they don't hurt and you're not afraid to take them," said Dr. Dan Henderson, a virologist and the CEO of Verndari, Inc.The biopharmaceutical company is based in Napa, California. Dr. Henderson originally came to the wine country to retire but stepped back into the lab during the Ebola crisis. He says some adults avoid vaccines because of a fear of needles, so Verndari set out to do something different. They created the VaxiPatch, a single-dose vaccination kit that uses a dermal patch with a metal microneedle array to deliver vaccines. Once applied, the person wears the patch like a Band-Aid for five minutes. The vaccine uses the COVID-19 "spike" protein that enables the virus to infect human cells and works to enhance a person's immune person.Unlike traditional vaccines, the patch doesn't need to be refrigerated, which Henderson says would make it easier and cheaper to send to developing countries. The company initially set out to make a flu vaccine but switched gears during the pandemic; they continue to adapt to the world's changing needs. "Now, for the First World, it's a shelter-in-place vaccine," said Henderson.They're working with the FDA to see if it could be mailed to your home. The vaccine would leave a temporary blue mark so the patient could take a photo and send it to their health care provider as proof of vaccination. In collaboration with the UC Davis, they've begun clinical trials in animals. Dr. Henderson says so far the results are promising.Other researchers are also working on getting a patch like this on people's arms.Scientists at the University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Center have created a fingertip-sized skin patch that is also showing promising results in animal testing. Verndari hopes to test its vaccine in humans in the fall, and if all goes well, it could be made available to the public early next year. Dr. Henderson believes they could manufacture about 20 million doses a month. "It would mean a lot because it's important to me to make a contribution and a contribution like that, to me, is priceless." 2408

has been born in Baltimore.The Maryland Zoo says the girl was born on Sunday, December 29, 2019, to 24-year-old chimpanzee Raven.“The baby is gripping well and is very vocal,” said Erin Cantwell, mammal collection and conservation manager. “Similar to many new moms, Raven needs a lot of support and encouragement. She’s a first-time mom, and we are using behavior training to guide her on how to carry and nurse the baby properly.”Raven was pregnant for about eight months. Raven is the second chimpanzee to give birth at the Zoo recently. In July 2019, the zoo welcomed baby Lola.Experts say developmental milestones for chimpanzees are similar to those for human babies. The staff will monitor the baby for important abilities, such as the ability to hold her head up on her own, use of her fingers and toes to grasp things, learning vocalizations and facial expressions, and teething.There are currently 14 endangered chimpanzees among the Maryland Zoo’s troop including the newborn. 989

Cost varies. Based on loan term, amount and down payment. For purchase loans, the premium ranges from 0.45% to 1.05%, according to the FHA. 142

YOSEMITE NATIONAL PARK, Calif. (AP) — No employee or resident has tested positive at Yosemite National Park's health clinic, and no visitors have reported being sick since the park began reopening last month, but tests of the park's raw sewage have confirmed the presence of the virus. Dozens of people are believed to have been infected. The public health officer for Mariposa County, who is overseeing coronavirus testing in the Yosemite area, said the emergence of the coronavirus will not likely lead to policy changes because the park is already following local and state restrictions. Eric Sergienko said he believes the confirmed presence of the virus in Yosemite will make people more vigilant. 710

With the talk of a possible COVID-19 vaccine on the way, some wonder if people who’ve recovered from COVID-19 should still get the vaccine.Months after his COVID-19 diagnosis, Robert Marrero’s road to recovery isn’t over. WFTS shared his story when he was released from the hospital in May.“Much better in the sense where I don’t have to struggle talking, but I’m still having difficulty with the brain fog. I’m still having problems with my walking, and the pain from my waist down to my toes,” said Marrero. “It’s very, very slow progress. It’s almost, I guess, [been] nine months already.”USF Health professor Dr. Marissa Levine explained that if you’ve already had COVID-19, the general recommendation they expect will be that you should get a COVID-19 vaccine when it’s approved and available.“Remember that what we’re looking at is an experimental authorization, that there’s a lot more to learn about this vaccine, so we don’t really know a lot about immunity yet, even for people who’ve had COVID, how long does that immunity last, let alone the immunity from the vaccine,” said Dr. Levine.Levine points to precedent, reminding people that vaccines are recommended for those who’ve had certain diseases before, like shingles. While it's believed to be rare, Levine says there is a potential risk of COVID-19 reinfection.“We know that you have immunity for some period of time,” said Levine. “It could be months, it could be longer, and like many other diseases, immunity duration really varies a lot by individuals.”Earlier this week, a CDC advisory committee voted to recommend both health care workers and long-term care facility residents be the first to get a COVID-19 vaccine when it becomes available. Levine says it’s important to keep an eye out for official recommendations for COVID-19 survivors, too.For long-haulers, the people who have lingering COVID-19 symptoms, Dr. Levine suggests people check in with their doctor first. But Marrero says if his doctor gives him the green light, he’ll sign right up.“Just try to be safe. Everything is all fine and dandy until you get it,” said Marrero.This story was originally published by Mary O'Connell at WFTS. 2182