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SAN DIEGO (KGTV) — The CDC is making plans to distribute millions of doses of a coronavirus vaccine by late next month, but government officials have gotten these predictions wrong in the past.Doctors and scientists say there are reasons to be skeptical of the timelines laid out by Operation Warp Speed based on the lessons of 2009 and 1976.During the height of the H1N1 Pandemic in 2009, San Diegans waited in long lines to get vaccinated only to find there were not many doses to go around.The CDC initially projected there would be 120 million doses of vaccine ready by October 2009. Then federal officials scaled back the projection to 45 million.By the end of October, only 23 million doses would become available due to delays in the manufacturing process.“The lesson of H1N1 is that you may make all the plans on paper, but the actual nuts and bolts of rolling it out is really challenging and not to be underestimated,” said Dr. Peter Chin-Hong, an infectious disease specialist at UC San Francisco.Manufacturers had trouble growing the H1N1 vaccine in chicken eggs, the most common method for producing flu vaccines. There were also issues with testing the vaccine’s potency and problems switching production lines from the seasonal flu vaccine to the H1N1 strain, according to an after-action report by the Department of Health and Human Services.A lot goes into making a vaccine, said Dr. Rahul Gupta of March of Dimes.“It's not just the vaccine but also the syringes, and the needles, and the stoppers, and the alcohol pads,” he said. “There are so many other things that go along when we talk about a vaccine.”By the time the vaccine was widely available, the pandemic had petered out.Experts say there are also some parallels to what happened in 1976.During the height of an election cycle, President Gerald Ford fast-tracked a vaccine after some soldiers on a military base in New Jersey got sick with a strain of H1N1, then called Swine Flu, that was genetically similar to the strain that killed millions in 1918.“Some scientists were telling Gerald Ford that this was going to be as bad as Spanish Flu,” said Dr. Chin-Hong.The U.S. launched a huge media campaign, urging Americans to get vaccinated.President Ford rolled up his sleeve and got the vaccine, along with one-quarter with the U.S. population, beginning in October of 1976.However, the viral strain they were worried about never spread beyond the military base, and there were rare side effects linked to the vaccine. Of the 45 million people inoculated, about 450 people developed Guillain–Barré syndrome and about 30 people died.One month after the vaccinations began, Ford lost the election and the episode became known as the “Swine Flu Affair.”Experts say it’s normal to have adverse reactions and production delays on the road to a vaccine.“We have to understand that’s a process. And we learn as we go along. And people have to trust the process as well,” Dr. Gupta said.But doctors say it’s a process that takes a lot of coordination, and there are aspects you just don’t want to rush. 3081

SAN DIEGO (KGTV) — The National Institutes of Health highlighted research Tuesday out of UC San Diego that could unlock a new way to treat COVID-19.The research reveals new insight into how the coronavirus hijacks cells, and how doctors might be able to set traps or decoys to combat the virus. The findings were published in the journal Cell last month.“It does open up another avenue for a potential treatment,” said UC San Diego distinguished professor Dr. Jeffrey Esko. “It’s not a cure. It would be something that would tamp down infection potentially.”Since January, scientists around the world have understood that SARS-Co-V2, the official name of the new coronavirus, enters cells by latching onto a specific receptor on the cell’s surface, called ACE2.The UCSD team, led by Dr. Esko and visiting scholar Dr. Thomas Clausen, discovered that this entry mechanism is actually a two-step process, and the virus must also attach to a long chain of sugars called heparan sulfate.“We’ve shown this is fundamental to the infectious mechanism, so it needs to be part of every study from now on,” said Clausen.All cells are coated with a complex layer of sugars, or carbohydrates, called glycans. Heparan sulfate is one type of glycan that is known to play a key role in the infection process in several viruses, including herpes and other coronaviruses.It’s a complicated process to picture so the researchers offer an analogy: imagine a bird, soaring over trees, hunting a worm on the forest floor. The bird is the coronavirus and the trees are the thick layer of glycans that coat the surface of the cell.To reach the worm, which in this case is the receptor ACE2, the bird must navigate its way through the trees, specifically through heparan sulfate.The UCSD found that by removing the heparan sulfate trees with an enzyme, they were able to prevent the virus from infecting cells. In laboratory testing, they also found a second technique worked to foil the virus: introducing more trees as bait.The team found that heparin, an FDA-approved drug that is similar in structure to heparan sulfate, successfully acted as decoy. Heparin is a widely used drug designed to treat blood clots. Since blood clots and strokes are common complications with COVID-19, many doctors already administer heparin to patients.The UCSD team demonstrated that the two approaches can block infection in lab-grown cells about 80 to 90 percent of the time.“Certainly in the laboratory you can demonstrate that it works, but to deploy it and use it as a therapeutic has not been demonstrated,” Esko said.The NIH noted that more studies are planned to explore whether heparin, heparan sulfate, or drugs that target heparan sulfate might yield a viable COVID-19 treatment.Dr. Esko said he’s already been in talks with companies that plan to use their study as a rationale for a clinical trial.“It is very humbling when you realize we’re working on a pandemic right now, and maybe what we’ve done can contribute to a treatment for the disease,” he said. 3038

SAN DIEGO (KGTV) -- The man accused of killing his wife in their City Heights apartment appeared in court Tuesday. Bail was set at million at the arraignment for Abdiaziz Kerow, 45, who was arrested in Panama on March 20 and extradited to San Diego.Kerow is accused of killing his 36-year-old wife, Muna Salad Kuri. Kuri’s sister found the victim’s body in a bed in the couple’s home on the 4000 block of Van Dyke Avenue on March 4. RELATED: Husband suspected of killing wife in City Heights apartment found, arrested in PanamaKuri had suffered traumatic injuries to her upper body, according to police. Hundreds of Kuri's family members as well as members of the community attended the arraignment. So many people showed up, the courtroom was unable to accommodate the crowd. The victim's sister, Amiina Salad said her sister was "sweet, humble, she's funny. She's always there for you, no matter what happens, she's there."Salad also had a message for Kerow. "My sister is in heaven. You're going to rot in here and you're going to rot in hellfire.''Somali community leader says this is the first time domestic violence death that has affected a Somali woman in their San Diego community. Kerow's next court appearance is scheduled for April 12. City News Service contributed to this report. 1304

SAN DIEGO (KGTV) - The federal watchdog agency that aims to protect consumers from unfair, deceptive, or abusive practices is suing a San Diego-based company.On Tuesday, the Consumer Financial Protection Bureau (CFPB) sued Encore Capital Group and its subsidiaries, claiming they violated the terms of a 2015 legal agreement.The CFPB claims, “Since September 2015, Encore and its subsidiaries violated the consent order by suing consumers without possessing required documentation, using law firms and an internal legal department to engage in collection efforts without providing required disclosures, and failing to provide consumers with required loan documentation after consumers requested it.”The lawsuit says after the effective date of the consent order, “Encore filed more than 100 lawsuits to collect consumer debts after the applicable statutes of limitations had expired."The lawsuit also claims Encore failed to disclose that consumers might incur international-transaction fees.In response to the lawsuit, the company's Executive Vice President, General Counsel, and Chief Administrative Officer Greg Call said Encore is built on a foundation of treating their consumers fairly and respectfully."We are disappointed that the CFPB has chosen to file this lawsuit on outdated issues, but we will continue to engage with the CFPB and work to ensure that we maintain policies and practices that fully comply with all applicable legal requirements. We believe that there will be no material operational impact as a result of the suit," said Call. "We fully corrected the issues underlying the allegations in this lawsuit years ago and are unaware of any unresolved consumer impact."DEBT COLLECTION LAWSUITSPart of the complaint talked about debt-collection lawsuits.In July Team 10 discovered a 157% increase in the number of rule 3.740 collections lawsuits filed in San Diego County court from 2015 to 2019. That involves any debt collection company."If you look not just in the county of San Diego, throughout the state of California, and in fact the dockets throughout the nation, we have a massive epidemic right now," said attorney Abbas Kazerounian during a July interview.Kazerounian said if someone's been sued or contacted by a debt collection company, they need to know their rights."The amount of debt is irrelevant," he said. "It's the method of collection that's controlled by these statutes."RESOURCES:Coping with debthttps://www.consumer.ftc.gov/articles/0150-coping-debtHelp available for renters, homeowners struggling to pay for housing during pandemichttps://www.10news.com/rebound/coronavirus-money-help/help-available-for-renters-homeowners-struggling-to-pay-for-housing-during-pandemic 2724

SAN DIEGO (KGTV) — The holiday season is underway in San Diego, as locals prepare to jump into December this weekend.Outdoor ice skating can be found at Viejas Casino and Resort's massive outdoor ice rink, and Carlsbad welcomes the "big man" to town to help light their Christmas tree!Legoland also jumps into the season with Holidays at Legoland and several street festivals and art shows give you the chance to get a jump on holiday shopping for friends, family, and pets!Not interested in anything here? Check out the 10News?community events calendar for a look at even more things to do!But Thanksgiving is first on the list. The 72nd annual Mother Goose Parade in El Cajon will ring in the season for being together with family and friends, as local gather to watch floats, bands, and Santa glide through town.Here's a look at this weekend's big events:THURSDAYOutdoor ice skating at ViejasWhere: Viejas Casino & Resort; Cost: - (Runs Thursday - Sunday) Holiday lights and entertainment have arrived at Viejas! Get into the winter spirit with ice skating at one of the biggest Southern California rinks around. A 90-minute session for kids will run while adults and teens can skate for . Art of the Holiday?ShowWhere: Fallbrook Art Center; Cost: Free(Runs Thursday - Saturday) Explore handmade crafts and jewelry by talented artists at Fallbrook Art Center's free Art of the Holiday Show. Wearable art, glass and ceramics, ornaments, and more can be found as a unique and creative gift this season! FRIDAYTree Lighting & Santa ArrivalWhere: Carlsbad Premium Outlets; Cost: FreeWelcome in the holiday season with Santa as he helps light Carlsbad's outlet Christmas tree. Enjoy holiday performances by Samantha Robertson, Singers Company, and the Carlsbad Company Theatre as well, and get a start on your holiday shopping. Del Mar Antique Show & SaleWhere: Del Mar Fairgrounds; Cost: Free(Runs Friday - Sunday) Del Mar Fairgrounds will be packed with vintage collectibles and antiques spanning glass, pottery, jewelry, art, and much more at the Antique Show & Sale. Have your own treasure? Appraisal team members can take a look and see if you've struck vintage gold! SATURDAYPadres Pedal the CauseWhere: Petco Park; Cost: - 5Pedal the Cause rallies the San Diego community to raise awareness and funding for cancer research in San Diego. The challenge includes four cycling courses, spin classes, or a 5K run/walk ending in centerfield inside Petco Park! You choose! Holidays at LegolandWhere: Legoland California; Cost: (Runs Saturday - Sunday) Holiday magic kicks off at Legoland, where a 30-foot high Lego Christmas tree will play centerpiece to a park full of holiday cheer. Make sure to visit Lego Santa and a cast of characters at the new Holiday Village! 10th Annual Doggie Street FestivalWhere: Liberty Station; Cost: FreeLiberty Station's Doggies Street Festival brings together live entertainment, auctions, and, of course, everything cats and dogs for pet owners and those looking to adopt a furry friend. Visit with rescue societies and get tips from vets and pet services, and bring your own doggo to enjoy the festival too!  SUNDAY72nd annual Mother Goose ParadeWhere: El Cajon; Cost: FreeEl Cajon's Mother Goose parade is billed as the largest parade in San Diego County! Celebrate Thanksgiving as thousands line the streets to watch Santa, marching bands, and more as the parade begins on Main St. at El Cajon Blvd. marching toward First St. 28th annual Encinitas Holiday Street FairWhere: Downtown Encinitas; Cost: FreeHead out for free fun in Encinitas, including two stages of live entertainment, delicious food, children's rides and games, and more during the Encinitas Holiday Street Fair. Vendors will also be out giving guests the chance to get some holiday shopping done, offering handmade crafts, art, and more! Taco TKOWhere: Liberty Station; Cost: Help discover San Diego's best taco during an all-you-can-eat taco showdown at Liberty Station! Taco TKO pits local restaurants against each other for the title of "San Diego's Most Awesome Taco," as part of the San Diego Bay Wine + Food Festival. 4299

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