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The first participant in a clinical trial for a vaccine to protect against the new coronavirus will receive an experimental dose on Monday, according to a government official.The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle. The official who disclosed plans for the first participant spoke on condition of anonymity because the move has not been publicly announced.Public health officials say it will take a year to 18 months to fully validate any potential vaccine. Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc. There’s no chance participants could get infected from the shots, because they don’t contain the virus itself. The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines — shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent. Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.Also in the works: Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing center in Kansas City, Missouri, followed by a similar study in China and South Korea.Even if initial safety tests go well, “you’re talking about a year to a year and a half” before any vaccine could be ready for widespread use, according to Dr. Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases.That still would be a record-setting pace. But manufacturers know the wait — required because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm — is hard for a frightened public.President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is “moving along very quickly” and he hopes to see a vaccine “relatively soon.”Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola. In the U.S., the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have COVID-19 after being evacuated from a cruise ship in Japan.For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia. The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the United States is more than 50, while infections neared 3,000 across 49 states and the District of Columbia. The vast majority of people recover. According to the World Health Organization, people with mild illness recover in about two weeks, while those with more severe illness may take three weeks to six weeks to recover.___The Associated Press receives support for health and science coverage from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. 3597

Thanksgiving Day has come and gone — but the holiday weather nightmare is not over just yet.As millions of holiday travelers head back home over the weekend, rain and snow will sweep through the Midwest on Saturday then push into the Northeast on Sunday into Monday, CNN meteorologist Haley Brink said.The storm system will cause widespread weather-related hazards through the Thanksgiving weekend as it tracks west to east across the lower 48, the 460

That scene from “Friends” when we find out Ross is still a patient at his pediatrician’s office is getting more common for young adults.One reason is young adults can stay on a parent's insurance until they are 26 years old so it's easier and more affordable to stick with the same doctor.There are downsides though.“If they start to get medical conditions, high blood pressure, hypertension, adult onset diabetes, those more … adult medical conditions, that’s an appropriate time to say, ‘hey maybe it’s time to transition to an adult provider,’ ” said Dr. Christina Johns with PM Pediatrics. The pediatric emergency physician says one benefit of staying on with a pediatrician longer is the patient continues to see someone familiar with their medical history, especially for those with chronic childhood health issues. And she says it prevents the young adults from moving into another trend she's noticing — relying solely on emergency room and urgent care only.“There really does seem to be a large group of adults who use those places as their primary care,” the pediatrician said. “It’s really important to have a relationship with a primary care doctor.”Johns says when young adults become parents and when women need regular OB/GYN care, those are also appropriate times to transition away from a pediatrician.The American Academy of Pediatrics discourages transitioning away from pediatric care solely based on age. Their position is that it’s a decision between a patient and their doctor. It should take into account meeting the needs of the patient and the abilities of the doctor. 1606

The mystery surrounding a little boy found sleeping on a Buffalo porch continues to grow. Buffalo Police updated the media late Tuesday morning, describing this as a, "very, very complicated case." Buffalo Police Captain Jeff Rinaldo says they are working closely with the boy's grandparents who recently arrived from Florida. The boy's grandmother tells 7 Eyewitness News reporter Ali Touhey the boy's name is Noelvin and that they intend to take custody of him. Meantime, we're told, the toddler's parents, 24-year-old Nicole Mersed and 31-year-old Miguel Valentin, haven't made contact with their family since Sunday. According to police, they will be issuing pictures of Noelvin's parents and a family friend, anyone with information on their whereabouts is asked to contact the department's homicide unit at 716-851-4466. The boy's grandmother tried to take custody of him, but that request was temporarily denied. She's expected to be back in Buffalo in October for a custody hearing. 1005

The American workforce isn't what it used to be."I saw an app that said 'dog sitting,' and I thought I could do that in my spare time," says gig worker Lawrence Snell. "It turned out that now I have up to six or eight dogs a day."For 40 hours a week, Snell takes care of other people's dogs through the app Rover.It's a temp job like Lyft, Uber, DoorDash, Postmates and others. It's the kind of work driving--what experts are now calling --"the gig economy". However, the concept isn't completely new. Americans have always worked odd jobs, but the number of people participating in them has gone up, due in part to advanced technology and wages not increasing. For most people, jobs like app-based deliveries or ride-sharing have been a little extra income on the side. But for a growing number of others, it's work that pays the bills without the commitment that comes with a traditional 9-to-5. "Going to work, clocking in, and working for the man… if I can do a gig where I can spend more time with my family and more time renovating my house and doing the things that I love, then yeah, that's more beneficial to me," Snell said says. Certain gig workers don't just stick to one job. Behailu Fitzjames spends his days working as many gigs as he can, turning everyday into a different adventure. Grubhub, Postmates, Uber Eats and Lyft are the main ones he’s a part of."Even some time I have left, I'll go on Craigslist gigs and look up who needs help, what's something new I could do," Fitzjames says. For Behailu it's been a steady source of income giving him freedom and flexibility to control his own schedule. "If you're driving around you can make 0 an hour with Lyft and Uber," Fitzjames says. "It's also varying, so that's kind of cool versus being at a fixed income."But it comes without the work protections many of us are used to having. The Trump Administration's labor department recently said it considers gig workers to be independent contractors. Not only are these workers allowed to control their hours, but they can also work for competing companies. However, the term "independent contractor" leaves them ineligible for things like overtime pay, workers compensation, and benefits. Most gig workers agree they'd like to see that change. "I think it should be offered, and I think it should be offered at a fair rate," Snell says. "I don't see why you should be punished for doing gig work."But some, like Behailu, are concerned that money for benefits would come out of their paycheck. "Being a contractor means you get to set everything up for yourself," Fitzjames says. "Having them offer insurance and all the benefits, I suppose, you wouldn't be making as much money, because more money would be trying to fund that."We partnered with Newsy and the polling firm Ipsos to further understand what people really think. We found most Americans believe gig workers should be afforded the same labor protections as full-time employees. Support for that among gig workers themselves is even higher. That could be because more people are working gigs full-time. The most recent data from the Fed shows that 18 percent of American gig workers rely on their gigs for their primary source of income. "Whether it's unemployment insurance, whether it's minimum wage protections, whether it's the ability to earn overtime - there's been a series of benefits and protections that built up over the course of the 21st century that you only can access if you're an employee," Al Fitzpayne, with Future of Work Initiative, explains. "And so, that is why the employee distinction is so significant relative to that of an independent contractor is a very important consideration." Gig workers are fully responsible for their own healthcare, retirement, and sick time, which can be a struggle, considering the money they're making may not be as much as some people think. For example, Uber once claimed its drivers in major U.S. cities were making between ,000 to ,000 a year. But recent data shows average hourly wages for ride-share drivers are much lower, and companies are taking a bigger cut. "All these companies are making lots of money, and it's time to spread that money around. I think they've got the money to do it, and I think they will do it eventually," Snell says. ********************************************************If you'd like to reach out to the journalist for this story, email elizabeth.ruiz@scripps.com 4458