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SAN DIEGO (KGTV) - After moving to San Diego almost three years ago, Derek and Terri Ruff are on a mission to experience everything the city has to offer. “Yes we are, it’s fantastic! We hardly leave the county, there’s just so much to do," said Derek.The couple moved here from New Mexico, and for nine years Derek's colon cancer seemed to be behind them. “I won’t say cancer-free, but I didn’t have any symptoms for years, until last May, whenever I came in for a checkup, and they discovered cancer again," said Derek.It was stage IV metastatic colon cancer.“It’s a lot. It’s a tough diagnosis, it’s really difficult to live through.”After three months of aggressive chemotherapy, Ruff's condition only got worse. His journey brought him to UC San Diego Health's Moores Cancer for a clinical trial, which unfortunately did not work. But he Ruff became a candidate for another trial involving natural killer cells created from stem cells.“These are patients who don’t have a lot of good options in terms of chemotherapy or immunotherapy," said Dr. Sandip Patel, a medical oncologist who is leading the trial at UCSD. Decades of research on natural killer cells have culminated in the new cancer treatment being developed by San Diego-based Fate Therapeutics.Fate is the first to mass produce cancer-killing cells from a type of stem cell called a human-induced pluripotent stem cell (iPSC). "The concept of utilizing the stem cells that are within us, within our blood factory, within our blood marrow, to create a master bank of cells that we can utilize to program in different ways to fight cancer with cellular immunotherapy."The off-the-shelf, iPSC-derived natural killer cell cancer immunotherapy received U.S. Food and Drug Administration approval to move into clinical trials in November 2018. Ruff is the first person in the world to receive the treatment and got his first dose in February.“Being the first is exciting but it was less so hearing that you have stage iv cancer and you don’t have much of a future, and now I feel hopeful, again," said Ruff.While it's too early to tell if the treatment is working, researchers are hopeful this treatment will one day help many cancer patients. 2212

SAN DIEGO (KGTV) - A San Diego nonprofit is hoping to tackle the homeless crisis with a creative solution.The nonprofit, Amikas, envisions a San Diego where every woman and child has a safe place to live in.They hope to build emergency sleeping cabins, which could temporarily house homeless women and children as they look for a permanent place to live. "They're small, they're immediate, they go up in a matter of days, and so we can house a lot of people very quickly with this solution," said Shanna Welsh-Levin, President of Amikas.Designed by San Diego-based Treecycling, the homes are inexpensive and can be built within 24 hours. The cabins are mobile, able to be dismantled within a few hours. "We built these things like houses so they feel like homes," said Gabriel Stafford, with Treecyling. The house built this week is on display at the Meridian Baptist Church in El Cajon. The ultimate goal would be to run a two-year pilot program, creating an emergency cabin village to test the idea. Welsh-Levin is inviting city leaders and the community to come to learn more about the effort. 1105

SAN DIEGO (KGTV) -- A second lawsuit has been filed by family members of a mother and daughter killed by a YouTube star in a deadly wrong-way crash last year.18-year-old Trevor Heitmann, known as McSkillet on YouTube, drove his McLaren the wrong way on I-805 in August 2018. The crash killed Aileen Pizarro and her 12-year-old daughter Aryana. This latest lawsuit was filed August 22nd by Angelo Pizarro and Arcelio Garcia. Pizarro is one of the sons of Aileen Pizarro. Garcia is the father of Aryana. A lawsuit earlier this summer was filed by Aileen Pizarro's other son, Dominic, and her father. The lawsuit claims wrongful death and negligence by the City of San Diego and the County of San Diego. The family is also suing Heitmann’s estate. It states that San Diego police received a “mental case” call that Heitmann was “screaming, paranoid and delusional and threatening to harm his mom.”Police were advised by a licensed psychiatrist that Heitmann needed to be “possibly placed on a 5150 mental hold,” according to court records. However, officers did not speak to or evaluate Heitmann to determine if he was a danger to himself or others. The lawsuit also states that “one or more of the Police Officers represented or implied that they were part of a San Diego County Psychiatric Emergency Team.”Team 10 reached out to both county and city officials. As of Wednesday afternoon, there was no comment regarding the lawsuit from the city. A county spokesperson said they have not seen the lawsuit yet. Cynthia Chihak, the attorney for Pizarro and Garcia, sent Team 10 a statement which reads in part:"I am privileged to represent Angelo Pizarro, the son of Aileen Pizarro, and Arcelio Garcia, the father and sole heir of twelve year old Aryana Pizarro, who were killed on August 23, 2018 when their car was struck head-on by a McLaren automobile driven by Trevor Heitmann... This family is not excusing Mr. Heitmann’ s reckless behavior, but believe this tragic loss of three lives could have been prevented if the City of San Diego has taken seriously earlier reports of his violent and dangerous behavior. The loss suffered by this young man Angelo, of his mother and sister and the loss to Mr. Garcia of his daughter can never be rectified. But with this lawsuit they hope to bring to light the inaction of the City and prevent any other family from suffering their grief."10NEWS RELATED COVERAGE:Popular YouTuber identified in wrong-way I-805 crash that killed mother, 12-year-old daughterYouTuber's parents requested psychiatric evaluation before deadly I-805 crashNeighbor says police were called to YouTuber's home the day he died in wrong-way freeway crashHow YouTuber in I-805 crash made small fortune with gaming videosSon remembers mother and sister after release of driver's autopsy in deadly 805 crash 2829

SAN DIEGO (KGTV) -- A school bus crashed into a San Diego Center for Children dormitory Wednesday afternoon, creating a massive hole in the side of the building.Officials say a San Diego Unified School District bus driver lost control of the bus on the 3000 block of Armstrong Street, causing the bus to collide with the building.No children were inside the building or the bus at the time of the crash. The bus driver was taken to the hospital as a precaution.Contractors have responded to the scene of the crash to assess the damage to the building. Officials with the center say all eight rooms in the dormitory are unusable following the incident. 659

SAN DIEGO (KGTV) - An Orange County-based company believes it could change the current healthcare landscape with one-hour COVID-19 testing.According to officials at Fluxergy, initial tests by researchers using a synthetic SARS-CoV-2 virus suggest this system has the potential to change the landscape for point-of-care diagnostic testing for COVID-19. It would dramatically reduce the time it takes to get results and deliver those results directly at the patient’s bedside. The company said it could be able to identify the virus in as little as 45 minutes."The typical laboratory tests that you do in a central lab or the doctor's office, you collect the sample and get that sent out to a central lab," said Fluxergy President Tej Patel. "We do those same types of tests, but in a single device, I want to say that's the size of a small PC or a shoebox-size device."Last week, the research team at UC San Diego began an initial benchtop evaluation of the Fluxergy system using the SARS-CoV-2 virus from patients in San Diego the company said.Patel told 10News Fluxergy technology aims to take that same test, put it in a single device, and make it portable. He said the changes to the system will make for easier access by removing some medical barriers."Our goal is to kind of democratize testing and increase the accessibility to testing," Patel said. "So when you try to focus your system more on point-of-care testing, where you make testing much easier to gain access to, where you don't have to go through your doctor or other provider, and not have to worry about reimbursement. If you can just go and do these tests, it's going to really elevate in general the whole healthcare system.""We need to test and test," said UC San Diego’s Dr. Davey Smith. "The countries that have done best to lower their mortality have done best by flattening the curve by testing where the infections are happening and knowing who's getting infected."Dr. Davey Smith is the head of the UCSD Division of Infectious Diseases and Global Public Health.Smith said immediate testing would give doctors an advantage."It's only going to be in certain situations, really point-of-care contact, and it will be for special circumstances that we’ll be able to make clinical decisions on right away," Smith said.According to Fluxergy, "The Fluxergy system is currently available as a Research Use Only, or Investigational Use Only device for the development of new diagnostic products. The Fluxergy system has not yet been reviewed or approved by the FDA. However, as noted, if the physician-scientists at UCSD obtain promising validation results using the system, they intend to begin immediate use of the diagnostic consistent with FDA's guidance and pursue an Emergency Use Authorization (EUA). An EUA would then enable the UCSD CLIA-certified diagnostic laboratory to continue to utilize the Fluxergy system with patients who need to be tested for the SARS-CoV-2 virus, subject to the terms and conditions set forth by FDA in the authorization." 3035

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