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A protester was accidentally run over and killed by a car during a demonstration over rising fuel prices, a top official in eastern France said Saturday.Mass demonstrations causing roadblocks across the country are part of the "gilets jaunes" or "yellow vests" movement, which opposes mounting gas prices and eco-taxes on polluting forms of transport.The death occurred when a driver "panicked" and ran over someone after arriving at a blockade for an undeclared protest not far from the city of Lyon, Louis Laugier, the prefect of the Savoie region, said at a news conference.A further 227 people were injured -- six severely -- in protests across the country, and 73 people were taken into police custody, the Interior Ministry said in a statement. Five police officers suffered slight injuries, and one was severely injured. Another five gendarmes were hurt as well.Speaking about the death, French Interior Minister Christophe Castaner said: "That's the reason why we were worried to have people (who are) not experienced organizing protests."Ecology Minister Fran?ois de Rugy called on citizens to "respect caution and safety recommendations" in order for protests to go ahead "without a new tragedy," in a tweet Saturday. He also offered his condolences to the family of the victim.More than 1 million people were expected to turn out Saturday for demonstrations across the country. Partway through the day, the numbers were much lower than that.About 280,000 people participated in more than 2,000 demonstrations, the Interior Ministry said."Honestly we're satisfied, even if it's true we are not hundreds of thousands people here, but still, people have come. The day is not over yet, and we're glad that there are no incidents here," Thierry Paul Valette, who helped organize a protest on the Champs Elysées in Paris, told CNN."We can't stand Macron's taxes any more. It's too much. We couldn't make ourselves heard through political parties or trade unions, so we had to do something."The protest was billed as likely to be one of the toughest tests yet of Emmanuel Macron's 18-month-old presidency.Website blocage17novembre said protests were planned in all 95 of France's mainland departments, while a petition on change.org calling on the French government to lower the cost of fuel has gotten more than 850,000 signatures.In addition to concerns over spiraling fuel prices, the protests also reflect long-running tensions between the metropolitan elite and rural poor. 2490

A viral video of a police officer hitting a 14-year-old girl during an arrest has caused outrage in a Florida community.The video -- posted to Instagram on Friday -- shows a girl being held down by two officers, one man and one woman. The male officer hits the girl in the side twice as he holds her shorts."Why you hitting her?" someone in the video yells. "She can't do that, her hands underneath her, the f*** you hitting her for?"The police department in Coral Springs, about 29 miles northeast of Fort Lauderdale, said in a statement on Facebook on Friday that the video does not show the entire incident that led to the arrest. 641

A surge in COVID-19 cases is further straining the already-depleted supply of prescription drugs in the U.S., according to researchers and doctors at the University of Minnesota."The supply lines are really stressed and stretched," said Dr. Stephen Schondelmeyer, a co-principal investigator for the Resilient Drug Supply Project at the University of Minnesota.Schondelmeyer's work focuses on critical drugs and their supply chains. He tracks the supply chain process for every drug on the marketplace — more than 100,000 in total.Most of the prescription drugs used by Americans are made outside of the country — meaning the U.S. is reliant on foreign companies to manufacture the drug and shipping companies to deliver them safely."We're identifying where it comes from — the first thing you need to know is about 70% of all the drugs that come into the U.S. marketplace are made outside of the US.," Schondelmeyer said.He and his team want to predict and identify when and where there will be failures in the system. Right now, the U.S. has a "fail and fix" system — and right now, there are some critical breakdowns in the supply chain."Seventy-five percent of the COVID-19 drugs are currently in shortage," Schondelmeyer said. "That means three-fourths of the drugs we're using for COVID-19 were already in shortage, and that's before we had this last surge we're seeing.""We should, as a matter of national policy, have a map like we're building of the global drug supply from the beginning all the way until the drug reaches the patient," Schondelmeyer said.But it's not just COVID-19 drugs that are in short supply. Dr. Beth Thielen, an assistant professor of pediatrics at the University of Minnesota Medical School and an infectious disease physician, says even some routine drugs are hard to come by."As a physician working in the hospital — the University of Minnesota — we're a big urban center and yet we're regularly dealing with this issue of shortages in routine things like antibiotics," Thielen said. "It's very concerning to think about the supply chain breaking down and seeing drugs not available in pharmacies or the hospital."Doctors say COVID-19 has unmasked a problem that's been a concern for decades. The pharmaceutical supply chain is complicated and dependent on other countries — and there are supply and demand dilemmas."Start the conversation now with your healthcare provider," Thielen said. "There might be some within class substitutions of medicines, so a drug that is related may not be the exact same drug but might fulfill the same purpose."Schondelmeyer adds that anyone with a regular prescription should ask their doctor about getting a 90-day supply of essential drugs — but adds that there's no reason to hoard medication."We shouldn't panic. We shouldn't treat drugs like we did toilet paper and stock up on so much that we're totally out — and that's an example of what can happen when there's rumors of shortages," Schondelmeyer said. "People act out of fear, and they hoard more than they really need."In the meantime, Schondelmeyer is pushing for a national stockpile of critical medications, so that the U.S. is covered should there be a complete breakdown in the supply chain. 3236

A short stint as a car salesman taught me that dealers are pros who negotiate all day for a living — and they always have the home field advantage.Later, while buying dozens of test vehicles for an automotive website, I was on the other side of negotiations, and experienced the tricks dealers use to pressure buyers.I’ve found that simple, nonconfrontational negotiating tactics can help even car shoppers who hate to haggle still get the best deal possible. These strategies, combined with online tools, can keep car shopping from turning into a battle with the dealer.Here are five ways to level the playing field:1. Know your numbers 650

A report released from the Centers for Medicare and Medicaid Services says a patient died after a nurse at the Vanderbilt University Medical Center in Nashville selected the wrong medication to give them, putting at risk the hospital's ability to receive Medicare payments.In fact, the paralyzing anesthetic that was given to the patient by mistake is one of the drugs Tennessee uses to execute death row inmates during lethal injections.The incident happened in December of 2017. According to a report conducted by CMS, the patient checked into the hospital with a subdural hematoma and vision loss.The patient was sent to the hospital’s radiology department for a full body scan. When the patient told caregivers they were claustrophobic, doctors prescribed Versed, a standard anti-anxiety sedative.  The report from CMS said a nurse told the patient they were going to give them "something to help him/her relax."The patient instead received a dose of vecuronium from that unnamed nurse.  Vecuronium is a neuromuscular blocking drug that causes paralysis.  As such, the CMS report says it can also stop the body from being able to breathe, in a painful experience for patients, who remain conscious and aware."Patients can experience intense fear when they can no longer breathe.  They can also sense pain," 1418

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