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INDIANAPOLIS — The U.S. Food and Drug Administration on Monday granted emergency use authorization to Eli Lilly and Company's experimental COVID-19 antibody treatment bamlanivimab.According to a statement from the company, the drug is authorized for the treatment of mild to moderate COVID-19 in adults and pediatric patients 12 years and older with a positive COVID-19 test who are at high risk for progressing to severe COVID-19 and/or hospitalization. Lilly said in a statement the drug should be administered as soon as possible after a positive COVID-19 test and within 10 days of symptom onset. The authorization allows for the distribution and emergency use of bamlanivimab, which is administered via a single intravenous infusion."This emergency authorization allows us to make bamlanivimab available as a COVID-19 treatment for recently diagnosed, high-risk patients — adding a valuable tool for doctors fighting the now-increasing burden of this global pandemic," David A. Ricks, Lilly's chairman and CEO, said. "The rapid development and availability of bamlanivimab could not have been achieved without the relentless work of our Lilly team, collaboration across the industry and the urgent work being done by the government to ensure appropriate allocation to patients who need it the most."The emergency use authorization is based on data from BLAZE-1, a randomized, double-blind, placebo-controlled Phase 2 study in patients with recently diagnosed mild to moderate COVID-19 in the outpatient setting. Patients treated with the drug showed reduced viral load and rates of symptoms and hospitalization, Lilly said in the statement. Infusion reactions and other allergic hypersensitivity events have been reported, Lilly said. The emergency use authorization includes a warning for hypersensitivity including anaphylaxis and infusion-related reactions.Lilly said the drug is not authorized for use in patients who are hospitalized due to COVID-19 or who require oxygen therapy due to COVID-19 or who require an increase in baseline oxygen flow rate due to COVID-19 in those on chronic oxygen therapy due to underlying non-COVID-19 related comorbidity."The BLAZE-1 data show bamlanivimab, when given early in the disease course, may help patients clear the virus and reduce COVID-related hospitalizations, supporting our belief that neutralizing antibodies can be an important therapeutic option for patients fighting this virus," Daniel Skovronsky, M.D., Ph.D., Lilly's chief scientific officer and president of Lilly Research Laboratories, said. "We're proud of the speed with which we have been able to bring patients this therapy specifically designed to treat COVID-19. We thank those who have contributed to this medical advancement, particularly the clinical trial investigators and participants around the country." This article was written by Bob Blake for WRTV. 2906
On his urban farm, Sean Conway is doing more than cultivating his next crop. He's helping grow the next generation of farmers. Conway is a mentor at the GoFarm incubator program, which pairs young farmers with established ones. “I wish that there was like an incubator program available to me in the Denver area at the time, because it would have helped me out a lot,” Conway says. After seven years of farming, Conway says he struggled at first. “I didn't really have enough experience to start farming on my own, so I made a lot of mistakes,” he admits. Now, the GoFarm incubator program is making sure these apprentices don't make the same mistakes Conway did. The program is a mix of hands-on training and classroom work, creating a path to farm ownership. “Two percent of the U.S. population is actually in an agricultural career, which is pretty crazy, so trying to increase the amount of farmers we have will affect the entire community,” says Natalie Fioretti with GoFarm. Apprentice Shelby Johnson knew she wanted to be a farmer, but had no idea where to begin.“The odds are really, really stacked against young farmers in a lot of ways, and especially as a young, queer woman of color from the south, it's like quadra stacked against me,” Johnson says. Johnson says thanks to GoFarm, she has resources and opportunities to network, while learning from older farmers.There are farming training programs like GoFarm across the country. GoFarm’s program lasts two years, with the hope of its benefits lasting much longer. For more information on the GoFarm program and its mission, 1602
Despite being the most watched sport in the country, fewer young people are playing tackle football. And while 7th grader Andrew Ek dreams of playing in the NFL, Brigid Ling worries about what the sport can do to Andrew’s and her own son’s brains. “When our oldest son was 8 he was begging us to move on from flag football to play tackle,” Ling said. “And we just weren’t ready for him to play tackle football at that age.” A new survey found participation in tackle football for kids 6 to 12 years old, dropped more than 17 percent over the past five years. A big reason for the shift: brain injuries. After more than a decade of research, there’s hard evidence of a direct link between football and CTE - a brain disease caused by repeated hits to the head. “We just felt there had to be a good interim step for kids to play,” Ling said. So rather than find a new sport for their son to play, Ling and her husband created one. “We created TackleBar as a way to allow kids to make a transition step from flag football to tackle football,” she said. In TackleBar, players hit but they don’t tackle each other to the ground. The goal is to wrap up and rip off foam bars harnessed on other player’s lower backs. Tacklebar coach Logan U’u grew up in a city that embraced hardnose football. “Playing football in Oakland, man, you got guys like Marshawn Lynch out there in your league,” U’u said. “We’re just little kids just cracking heads every single play.” Earning a football scholarship to the University of Minnesota, U’u knows about the sport’s rewards. He also knows about the risks like concussions. “You become nauseated to the point where you feel like you’re going to throw up and maybe you do throw up,” he said. “And then you feel like you want to cry but you can’t because you’re so confused. It’s a very bizarre feeling.” U’u says TackleBar teaches players proper tackling techniques and ultimately better prepares kids to transition to real take downs. Neurosurgeon and University of Minnesota researcher Uzma Samadani says TackleBar is much safer than both tackle and even flag football, and she has the research to prove it. “We published this paper in the Orthopedic Journal of Sports Medicine,” she said. “Basically, what we found was that the injury rate was seven-fold lower in the TackleBar kids versus the other kids” For two seasons, Samadani tracked 1,000 football players ages 9 to 15, and her findings showed a big spike in safety. “I think TackleBar makes athletes safer for two mechanisms,” she said. “One is reducing head-to-head contact and other is reducing head-to-ground contact.” Despite the study, Samadani says banning contact sports isn’t the ultimate answer – safer options are. “Now that we understand that the chronic effects of neurotrauma exist and they’re very serious we have to prevent it from happening in the next generation,” she said. Now entering its fifth season, TackleBar is attracting a new generation of young football players. “Last year we were over 8,000 kids in over 200 communities,” said TackleBar CEO Tim Healy. Healey says they plan on continuing to expand to teams across the country with the hope that TackleBar can reverse the trend and ultimately bring kids back to old-school football – when they’re ready. “It pains me when I see these schools where the numbers are down so much,” he said. “This is a way we can save the game.” 3447
Martha Firestone Ford is stepping down as the owner of the Detroit Lions, the team announced on Tuesday. Her daughter, Sheila Ford Hamp, will succeed her mother as the team's principal owner and chair.Martha, who is 94, has owned the team for six years."It has been a great honor for our family to be association with the Lions and with the National Football League. I am gratified that this family tradition, which my husband and I began almost six decades ago, will continue under Sheila's guiding hand. It is clear to me that Sheila will provide superb leadership and is fully committed to competitive excellence and community involvement," Martha said in a statement."My mother has inspired all of us since taking on the leadership of the Lions over six years ago. She has been a tireless leader to our family, our team, and our community. Her smart decisions have given me a solid foundation to take the team forward. On behalf of the family and the team, I want to thank her for her countless contributions. I look forward to leading the Lions to excellence on and off the field," Sheila said in a statement.When she took over for the team after her husband, William Clay Ford died, she became a fixture at practices and at games.“I’m so impressed by the way that she handles things, runs the team, is involved. She was out at practice last week, it was 90-some degrees, stood out there the whole practice. I mean, she might be in better shape than some of the players,” New England Patriots Head Coach Bill Belichick said during the NFL Films interview. He was speaking of a joint practice between the Patriots and Lions in the summer of 2019.“We have meetings, two or three times a week during the season. We’re at training camp together so we can talk about players that we see. It’s just such a big part of my life, I don’t know where it begins or ends,” she said in an NFL Films clip. “I don’t pretend to be an expert on coaching, but I know enough to be on top of what’s going on.”Ford was one of ten female owners in the NFL. WXYZ was first to report this story. 2098
President Donald Trump has arrived in Phoenix for a "Latinos for Trump" roundtable.The roundtable will take place at The Arizona Grand Resort Monday at around 3 p.m. The event page originally stated it was supposed to begin at 11 a.m., but the event was rescheduled Saturday afternoon. Watch live coverage of President Trump's visit in the player below. RELATED: ABC15's exclusive interview with President Donald TrumpTrump last visited Phoenix in June, where spoke at a "Students for Trump" event in north Phoenix. Vice President Mike Pence will be participating in multiple events in Phoenix Friday as well, according to White House officials.Both the Trump and Biden campaigns are increasing their outreach to Latino voters, who now make up the largest minority group in the U.S. and represent 24% of all eligible Arizona voters, according to the Pew Research Center.The Arizona Republican Party said Sunday, thanks to three community centers in Phoenix, Tucson and Yuma in Latino neighborhoods, the GOP has been able to connect with countless voters through a volunteer team of more than 1,100 people.Pam Kirby, who serves on the Latinos for Trump advisory board, told ABC15 their message is getting through to voters who have historically voted for Democrats. She believes Trump's platform aligns with those voters' values of faith, family and freedom along with job and economic security."Latinos are getting back to work and they felt money in their back pockets pre-coronavirus, and post-coronavirus we're already starting to see the 'great American comeback,'" she told ABC15 on Sunday.Still, Congressman Ruben Gallego (D-AZ) sees a different result, calling Trump "the worst President when it comes to Latinos in the history of Arizona.""We have been disproportionately impacted by COVID-19 due to this President's handling," he said. "Small businesses, small Latino businesses, have been shuttered because the President did not handle the coronavirus correctly." This story was first reported by KNXV in Phoenix, Arizona. 2058