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SAN DIEGO (CNS) - The Collaborative Clinical Trials Unit at UC San Diego has been selected to lead and administer an international seven-year, million grant for HIV/AIDS clinical trials.The National Institutes of Health selected UCSD, along with other American, South African and Indian research hospitals, as part of its seven-year HIV/AIDS funding renewal. Every seven years, NIH competitively renews its funding of the HIV clinical trials networks operating in the United States and internationally.During the current application process, the UC San Diego AntiViral Research Center, University of Colorado Hospital, Houston AIDS Research Team and Durban International clinical research sites were chosen to work collaboratively on research priorities for the NIH/National Institute of Allergy and Infectious Diseases HIV/AIDS Adult Therapeutics Clinical Trials Network.The Chennai Antiviral Research and Treatment Center, University of Southern California and University of Miami clinical research sites were also chosen to join UCSD to serve as qualified reserve or protocol-specific sites as needed for future clinical trials."UC San Diego has helped shape HIV/AIDS research and treatment through innovative research since the inception of the adult and pediatric therapeutic clinical trials networks in 1986," said principal investigator Dr. Constance A. Benson, director of UCSD's Antiviral Research Center."Together, the seven clinical research sites selected by the NIH for the HIV therapeutic clinical trials network bring together a wealth of scientific expertise, experience and the high quality performance required to conduct complex clinical trials," she said.Abouty 38 million people are living with HIV/AIDS globally, with 1.7 million acquiring HIV in 2019 alone. In the United States, 1.2 million people are living with the virus.The UCSD-led clinical trials unit serves several regions in the United States burdened by chronic and new HIV infections as well as global regions impacted by both HIV and tuberculosis.The unit will investigate therapeutic strategies aimed at a cure for HIV, including evaluating viral persistence, researching antibody approaches to treatment and prevention and investigating treatment of inflammation and its impact on HIV comorbidities.In addition, investigators will study new drugs including long-acting drug formulations for HIV treatment and prevention, HIV-related coinfections and comorbidities -- including metabolic and end organ complications and a hepatitis B cure, as well as the treatment and prevention of tuberculosis, including TB preventive vaccines, in persons with mono- and HIV-coinfection."We are honored to lead a talented pool of investigators in a common goal of advancing research that clinically benefits people living with HIV," Benson said. 2830

SAN DIEGO (CNS) - San Diego County health officials have reported 2,490 new COVID-19 infections and 14 new deaths, marking 104,958 total cases and 1,151 total deaths.Saturday marked the fourth consecutive day that more than 2,000 new cases were reported, with 2,867 cases -- a record -- reported Friday, 2,050 reported Thursday and 2,104 Wednesday. It is also the 12th day with more than 1,000 new cases. It is just the sixth time the daily cases have crossed 2,000 -- all of which have come in the past week.Of 27,599 tests reported Saturday, 9% returned positive.The number of hospitalizations continued to rise, with 38 people hospitalized and four patients put in intensive care units. The COVID-19- related hospitalizations increased to 965 -- 249 in ICUs. Since the pandemic began, 5,064 or 4.9% of cases have been hospitalized due to coronavirus, 1,098, or 1.1% have been sent to the ICU.The county's hospitals have 16% of their ICU beds available, down from 21% Thursday. The state now estimates the ICU bed availability in the 11- county Southern California region at 6.2%, down from 7.7% on Thursday.Of the 4,627 people hospitalized in the county, 20% are due to COVID- 19, and 44% of ICU patients. This compares to 7.7% and 20%, respectively, one month ago.The county has seen a 199% increase in COVID-19 related hospitalizations in the past 30 days and a 148% increase in ICU patients in the same time frame. The previous peak in hospitalizations, in mid-July, topped out around 400 patients.Seven new community outbreaks were reported Saturday. A community setting outbreak is defined as three or more COVID-19 cases in a setting and in people of different households over the past 14 days. 1711

SAN DIEGO (CNS) - The California State University Board of Trustees announced the appointment Wednesday of Ellen Neufeldt as president of the San Marcos campus.Neufeldt will become the university's fourth president when she takes over in July. She is currently the vice president of student engagement and enrollment services at Old Dominion University in Virginia.CSU officials had searched for and interviewed candidates for the Cal State San Marcos presidency since November."Dr. Neufeldt has been a visionary leader who has demonstrated a commitment to student success throughout her career," said CSU Trustee and search committee chair Jean Picker Firstenberg. "She brings a wealth of experience, and will serve as an inspirational leader on the campus and in the community."Current CSUSM President Karen Haynes announced last September that she plans to retire in June. Haynes, will leave office as the longest-tenured president in the university's history, helped increase the school's population from 7,000 in 2004 to the current 17,000 and added 15 new buildings and more than 100 academic programs.Neufeldt has held her current role at Old Dominion since 2011, overseeing government relations and marketing and public relations in addition to student engagement and enrollment services. Prior to joining Old Dominion, she also served as the vice president of student affairs at Salisbury University and assistant vice chancellor for student development at the University of Tennessee at Chattanooga.Neufeldt said she was looking forward to her new post."There has been remarkable growth both on the campus and in the local community and the opportunity for additional growth still remains," Neufeldt said. "This is an exciting time for the campus and the prospects are limitless." 1798

SAN DIEGO (CNS) - San Diego County public health officials reported 308 new COVID-19 cases and three additional deaths Sunday, raising the county's cumulative totals to 40,650 cases and 707 fatalities.Two women and one man died between July 29 and Aug. 31. Their ages ranged from the mid-50s to mid-90s. Two of the three had underlying medical conditions.San Diego County's state-calculated case rate is 5.8 and the testing positivity percentage is 3.8%.Of 4,271 tests reported as of Saturday, 7% returned positive, raising the county's 14-day rolling positive testing rate to 4.3%, well below the state's 8% guideline. The seven-day average number of tests performed in the county is 6,946.Of the total positive cases in the county, 3,214 -- or 7.9% -- have required hospitalization since the pandemic began, and 772 -- or 1.9% -- were admitted to an intensive care unit.County health officials reported two new community outbreaks as of Saturday, bringing the number of outbreaks in the past week to 20. One of the outbreaks was at a residence and one at a business.The number of community outbreaks remains well above the county's goal of fewer than seven in a seven-day span. A community setting outbreak is defined as three or more COVID-19 cases in a setting and in people of different households in the past 14 days.Under the new state monitoring metrics, San Diego County is in Tier 2, also referred to as the red tier.The county's next scheduled media briefing is Wednesday. Because of the Labor Day holiday, there will not be an update to the county's COVID-19 website on Monday.San Diego State University issued a stay-at-home order for students living in on-campus residence halls on Saturday, asking them to stay in their current residences except for essential needs throughout the weekend as the school battles an outbreak of the coronavirus.The order remains in effect through 6 a.m. Tuesday.The school reported another 120 confirmed or probable COVID-19 cases among its student population Friday, raising the university's total caseload to 184 since fall semester began Aug. 24."Students should stay in their current residences, except to take care of essential needs, including medical care, accessing meals, shopping for necessities such as food/meals and medical supplies, exercising outdoors (with facial coverings), and traveling for the purposes of work," a statement from SDSU read.Violations of the order may result in disciplinary consequences, the college said.Additionally, San Diego County public health officials confirmed multiple clusters of COVID-19 cases within the university community among students. This includes the previously announced off-campus outbreak on Wednesday. SDSU officials say none of the cases under investigation are related to on-campus educational activities, including classes or labs.Luke Wood, SDSU's vice president for student affairs and campus diversity, said the university was working with a security company to enforce public health code violations and had issued a total of 457 student violations through Friday afternoon. Wood said the most serious of these violations could result in suspension or expulsion from the university. Some organizations have been cited as well. Wood said the majority of these were fraternities or sororities, but followed up that not all were, and outbreaks impact the community at large regardless of the type of group they occurred in.All of the university's in-person classes -- which SDSU President Adela de la Torre said comprised just 7% of all courses -- were moved online Wednesday. SDSU also paused all on-campus athletics training and workouts for two weeks starting Thursday due to COVID-19."Only a small fraction of students have met in person," de la Torre said. SDSU has a student body of more than 35,000. Nearly 8,000 students live on campus.She cautioned that "testing alone and testing once" would not be enough, and a robust system to enforce health orders would continue to be needed to avoid the "plague of parties" already present near campus.SDSU has more than 130 spaces for students to safely quarantine, according to the university, and all students who have moved into campus housing would be able to move out if they so choose.County health officials warned that Labor Day weekend could be a spreading event for COVID-19."Most people won't be working over the long holiday period, but COVID- 19 will not be taking the day off," said Dr. Wilma Wooten, county public health officer. "The more people go out and the more they interact with people outside their household, the more likely they are to contract the virus." 4650

SAN DIEGO (CNS) - The San Diego Humane Society has changed its adoption process to a socially-distant experience, allowing prospective pet owners adhering to California's stay-at-home order to adopt a new furry friend from afar.An adoption counselor will call the prospective adopter to conduct a consultation over the phone to discuss available animals and help the adopter choose the pet which best fits their lifestyle. Once the pet is adopted, the adopter can drive up to the campus and staff will help safely load the animal into the adopter's car.RELATED:Amid COVID-19 closures, some San Diegans turn to pet adoptionSan Diego area puppy stores accused of selling dogs from puppy millsHelen Woodward launches 'critter cam' amid social distancingHumane Society campuses in Escondido, Oceanside and San Diego are open by appointment only each day from 10 a.m. to 4 p.m. Interested adopters should call the society at 619-299-7012 to make an appointment."The COVID-19 pandemic is presenting significant challenges for San Diego Humane Society's lifesaving work, but it is imperative that we continue to find homes for the animals in our care," said SDHS President and CEO Dr. Gary Weitzman. "The flow of animals into shelters will not cease due to this virus, so we are pleased to be able to continue providing adoption services in this way."San Diego Humane Society is encouraging any community member who is able to open their home and heart to a shelter pet in need. The organization currently has more than 100 pets available for adoption. 1553

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