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CLEVELAND — Scientists at the Cleveland Clinic Lerner Research Institute have successfully reversed Alzheimer's disease in mice.According to a news release, the researchers reversed the formation of harmful plaque in the mice's brains by gradually reducing an enzyme called BACE1, improving their mental function.“To our knowledge, this is the first observation of such a dramatic reversal of amyloid deposition in any study of Alzheimer’s disease mouse models,” says Riqiang Yan, one of the scientists on the team. The study raises hopes that drugs aimed at this same enzyme will soon be able to treat Alzheimer's disease in humans. You can read the full study in the Journal of Experimental Medicine here. 735
COSTA MESA, Calif. (AP) — The Los Angeles Chargers could explore bringing in Colin Kaepernick for a workout depending on what happens during the preseason, but right now, nothing is scheduled. Coach Anthony Lynn says Kaepernick is on the team's workout list because he fits the style the Chargers are looking for. "I'm very confident and happy with the three quarterbacks that I have, but you can never have too many people waiting on the runway," Lynn said, per ESPN's Lindsey Thiry.Per NFL Network's Omar Ruiz, Lynn thinks that Kaepernick “fits the style of quarterback for the system we’ll be running.” 613

Crazy Horse III strip club is preparing for the arrival of their new neighbors, the Las Vegas Raiders, by introducing a daily "Hard Hat Happy Hour" from 4 p.m. to 7 p.m. starting Wednesday, Nov. 8.The promotion will help the Raiders stadium’s construction crew unwind from long days of work by offering a complimentary drink each hour of the daily special. All it will take is for workers to present their work card or pay stub upon arrival.Oh, did we forget to mention that they will be granted free entry to the club as well?Crazy Horse III is just minutes away from the future site of Raiders stadium, which means workers, fans and players should expect a lot more of these specials to be announced as 2020 draws near. 735
CORONADO, Calif. (KGTV) — You may not find a cowardly lion, brainless scarecrow, or heartless Tin Man on Coronado, but the city's connection to one of history's most famed stories runs deep."Wizard of Oz" author L. Frank Baum has several connections to the scenic beach city. Between 1904 to 1910, Baum and his family vacationed in the city often, according to San Diego's tourism website.Baum was reportedly such a fan of Coronado's beauty, he wrote a portion of the "Oz" series there. SD FAIR 2019: What to know | Admission discounts | Parking and transportation | Rides and games | Concert headlinersAnd his links can still be found around town:Baum's Coronado homeThe Coronado home L. Frank Baum rented on Star Park Circle still stands today. While it's not open to the public (it's a private residence, so view from the sidewalk), the property is the sight where Baum wrote "Dorothy and the Wizard of Oz," "The Emerald City of Oz," "The Road to Oz," and portions of "The Marvelous Land of Oz."The home's owners haven't shied away from the notoriety either. A small "wicked witch" can be seen from the side of the house and a "ding dong" witch doormat.The Hotel Del CoronadoBaum and his family were known to visit the Hotel Del often in the early 1900s. Hotel officials say the author would reside at the Del for months at a time.The Crown RoomThe hotel's links run even deeper with Baum. The regal chandeliers in the hotel's "Crown Room" were designed by Baum.Rare "Wizard of Oz" first editionsCoronado's Museum of History and Art have three rare first editions of Baum's "Oz" series on display. Admission to the museum is free, making it even easier to take in literary history."Oz" art exhibitInside the Coronado Public Library, an elaborate work of "Wizard of Oz" characters and scenes on nine glass panels are on display. The artwork shows Dorothy, the cowardly lion, scarecrow, and Tin Man as an ode to Baum's stories.Baum-inspired "Author's Study"Another nod to Baum can be found at the 1906 Lodge at Coronado Beach. The bed and breakfast's "Author's Study" is decorated with art prints of the "ruby slippers," characters from the "Oz" series, a writing desk, and autobiaography on Baum. "The Queen of Fairyland"A poem by Baum submitted to the San Diego Union in 1905 speaks of the author's love and inspiration for Coronado. The poem, titled "Coronado: The Queen of Fairyland," speaks of "enjoyment stranger and grand" and "dreams are sweet and moments fleet."This year, the San Diego County Fair celebrates Baum and his stories under the exciting theme of "Oz-some," putting foods, exhibits, and experiences themed after the author's works on full display. 2678
CORSICANA, TX — Three juveniles in Texas have been arrested on felony charges after allegedly drinking from two juice bottles inside a Walmart store then putting them back on the shelves.The Corsicana Police Department says around 10 p.m. on August 23, officers were made aware of a Facebook post that showed a video of a suspect taking a drink from two separate juice bottles then putting them back on the shelves at Walmart.Walmart's management removed the products from the shelves as soon as they were made aware of the incident.All three suspects were identified and taken into custody. They have been charged with tampering with consumer product, a second degree felony.Since all suspects are age 16 or younger, they are considered juveniles, which prohibits law enforcement from publicly identifying them.This article was written by Sydney Isenberg for KXXV. 873
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