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WASHINGTON, Sept. 14 (Xinhua) -- Controlling diabetes may someday involve mining stem cells from the lining of the uterus, Yale School of Medicine researchers report in a new study published Wednesday in the journal Molecular Therapy. The team treated diabetes in mice by converting cells from the uterine lining into insulin-producing cells.The endometrium or uterine lining, is a source of adult stem cells. These cells generate uterine tissue each month as part of the menstrual cycle. Like other stem cells, however, they can divide to form other kinds of cells.Led by Yale Professor Hugh Taylor, the researchers bathed endometrial stem cells in cultures containing special nutrients and growth factors. Responding to these substances, the endometrial stem cells adopted the characteristics of beta cells in the pancreas that produce insulin. Over the course of a three- week incubation process, the endometrial stem cells took on the shape of beta cells and began to make proteins typically made by beta cells. Some of these cells also produced insulin.After a meal, the body breaks food down into components like the sugar glucose, which then circulates in the blood. In response, beta cells release insulin, which allows the body's cells to take in the circulating glucose. In this study, Taylor and his team exposed the mature stem cells to glucose and found that, like typical beta cells, the cultured cells responded by producing insulin. The team then injected diabetic mice with the mature, insulin-making stem cells. The mice had few working beta cells and very high levels of blood glucose.Mice that did not receive the stem cell therapy continued having high blood sugar levels, developed cataracts and were lethargic. In contrast, mice that received the cell therapy were active and did not develop cataracts, but the animals' blood sugar levels remained higher than normal.The Yale team's findings suggest that endometrial stem cells could be used to develop insulin-producing islet cells, which are found in the pancreas. These islet cells could then be used to advance the study of islet cell transplantation to treat people with diabetes.Taylor said in a statement that the next step in the research will be to verify how long this treatment remains effective.

SAN FRANCISCO, June 9 (Xinhua) -- Hewlett-Packard Co. (HP) on Thursday announced that its tablet computer, HP TouchPad, will go on sale in the United States on July 1.Two versions of HP TouchPad, with the option of either 16 gigabytes or 32 gigabytes of internal storage, and both only with Wi-Fi connection, will be available in the United States for 499. 99 U.S. dollars and 599.99 dollars respectively, the company said in a statement.The product will hit stores in Britain, Ireland, France and Germany a few days later and in Canada in mid-July, with availability scheduled to follow later this year in Italy, Spain, Australia, China's Hong Kong, New Zealand and Singapore.Preorders in North America and Europe will begin on June 19, HP said.HP did not release the price details when it introduced TouchPad on Feb. 9. The black device, with a 9.7-inch touch screen, runs webOS operating system, a mobile platform developed by Palm, a smartphone maker acquired by HP last April for 1.8 billion dollars.

STOCKHOLM, July 7 (Xinhua) -- A patient has been given a new trachea made from a synthetic scaffold seeded with his own stem cells in a Stockholm's hospital, the Swedish medical university Karolinska Institutet said on Thursday.The operation was performed on June 9th at Karolinska University Hospital in Huddinge and the patient, a 36-year old man, has been well on the way to recovery and would be discharged from the hospital on Friday, the university said in a statement.The patient had been suffering from late stage tracheal cancer with the tumor had reached approximately 6cm in length and was extending to the main bronchus.Since no suitable donor windpipe was available, the transplantation of the synthetic tissue engineered trachea was performed as the last possible option for the patient.The successful transplantation of tissue engineered synthetic organs, referred to as regenerative medicine, could open promising therapeutic possibilities for the thousands of patients who suffer from similar conditions.Transplantations of tissue engineered windpipes with synthetic scaffolds in combination with the patient's own stem cells as a standard procedure means that patients would not have to wait for a suitable donor organ.This would be a substantial benefit for patients since they could benefit from earlier surgery and have a greater chance of cure, according to the statement.

BEIJING, August 3 (Xinhuanet) -- Women who experience any form of gender-based violence are at greater risk of mental health disorders and related dysfunction and disability, according to Australian researchers Wednesday.Those who'd been through at least one form of this abuse -- which includes intimate partner violence, rape, sexual assault, or stalking -- were almost three times more likely to experience a mental health condition than those who were never victimized, according to Susan Rees, PhD of the University of New South Wales in Sydney, Australia, and her colleagues.Those who'd experienced three or four forms had an 11-fold greater risk, reported in the Aug. 3 issue of the Journal of the American Medical Association.The study "reveals a pattern of social disadvantage, disability, and impaired quality of life among women who have experienced gender-based violence," the researchers wrote.

LOS ANGELES, June 17 (Xinhua) -- The size of low-oxygen zones created by respiring bacteria is extremely sensitive to changes in depth caused by oscillations in climate, thus posing a distant threat to marine life, a new study suggests."The growth of low-oxygen regions is cause for concern because of the detrimental effects on marine populations -- entire ecosystems can die off when marine life cannot escape the low- oxygen water," said lead researcher Curtis Deutsch, assistant professor of atmospheric and oceanic sciences at University of California, Los Angeles."There are widespread areas of the ocean where marine life has had to flee or develop very peculiar adaptations to survive in low- oxygen conditions," Deutsch said in the study to be published in an upcoming print edition of the journal Science.A team led byDeutsch used a specialized computer simulation to demonstrate for the first time that fluctuations in climate can drastically affect the habitability of marine ecosystems.The study also showed that in addition to consuming oxygen, marine bacteria are causing the depletion of nitrogen, an essential nutrient necessary for the survival of most types of algae."We found there is a mechanism that connects climate and its effect on oxygen to the removal of nitrogen from the ocean," Deutsch said. "Our climate acts to change the total amount of nutrients in the ocean over the timescale of decades."Low-oxygen zones are created by bacteria living in the deeper layers of the ocean that consume oxygen by feeding on dead algae that settle from the surface. Just as mountain climbers might feel adverse effects at high altitudes from a lack of air, marine animals that require oxygen to breathe find it difficult or impossible to live in these oxygen-depleted environments, Deutsch said.Sea surface temperatures vary over the course of decades through a climate pattern called the Pacific Decadal Oscillation, during which small changes in depth occur for existing low-oxygen regions, Deutsch said. Low-oxygen regions that rise to warmer, shallower waters expand as bacteria become more active; regions that sink to colder, deeper waters shrink as the bacteria become more sluggish, as if placed in a refrigerator."We have shown for the first time that these low-oxygen regions are intrinsically very sensitive to small changes in climate," Deutsch said in remarks published Friday by the American Association for the Advancement of Science on its website. "That is what makes the growth and shrinkage of these low-oxygen regions so dramatic."Molecular oxygen from the atmosphere dissolves in sea water at the surface and is transported to deeper levels by ocean circulation currents, where it is consumed by bacteria, Deutsch said."The oxygen consumed by bacteria within the deeper layers of the ocean is replaced by water circulating through the ocean," he said. "The water is constantly stirring itself up, allowing the deeper parts to occasionally take a breath from the atmosphere."A lack of oxygen is not the only thing fish and other marine life must contend with, according to Deutsch. When oxygen is very low, the bacteria will begin to consume nitrogen, one of the most important nutrients that sustain marine life."Almost all algae, the very base of the food chain, use nitrogen to stay alive," Deutsch said. "As these low-oxygen regions expand and contract, the amount of nutrients available to keep the algae alive at the surface of the ocean goes up and down. "Understanding the causes of oxygen and nitrogen depletion in the ocean is important for determining the effect on fisheries and fish populations, he said.

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