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SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053

SAN DIEGO (KGTV) -- It used to be a landline was the source of unwanted phone calls, but now it's our cell phones.Glynnis Hubbard, like countless other Americans, is frustrated and fed up with the constant ringing, "Between 5 and 10 I'd say a day sometimes.""I had one today about an expired warranty. It didn't say about what, but somebody who's a little less savvy will call that number back and give them who knows what information," Hubbard said. And that's where it becomes more than just annoying, robocalls and scammers can be costly and even dangerous. RELATED: Americans received 4.1 billion robocalls in JuneJonathan Sasse and his team at First Orion specialize in call management. According to their data, nearly half of all the calls to our cell phones will be scammers as of 2019.But there are things you can do. First, check with your carrier about the services they offer.  The next option is an app for your phone. Depending on your device there are several out there. "They aren't foolproof but its better than nothing and it's a good opportunity to give you a window into who's calling you and why they might be calling you, " said Sasse.RELATED: 'Spoofing' scams steal your phone number; How to protect yourself from robocallsAnd if you're wondering about that "Do Not Call List", Sasse has an explanation,   1380

SAN DIEGO (KGTV) - Monday activist groups rallied at events throughout the day with the same message, more needs to be done to stop police brutality."My son was not killed he was murdered," Richard Abuka's son, Alfred Olango, was shot and killed by police in El Cajon back in 2016.Monday morning he stood on the steps of the Hall of Justice with other activists dredging up tragedy, compelling people to hear their message that new policies to hold police accountable need to be put in place. They held a banner with the names of those lost at the hands of law enforcement throughout the county."I've been pulled over numerous times, ripped out of my car, my car searched just because I'm driving with tattoos," a former convict by the nickname "Flaco" said at the Teach-In event held at San Diego City College.The events all supporting the National Day of Actions to Stop Police Brutality."We don't need cops," panelists spoke on ways to find a solution."I do work with the police and the DAs department in training their officers, and I help run a restorative justice program that's city wide and I'm expanding it to county wide," Aeiramique Blake said. Blake

SAN DIEGO (KGTV) - Loved ones are mourning the loss of a City Heights man and longtime professional wrestler to COVID-19.In the wrestling ring, Martin Rodriguez was known as "Espantito," or "The Terror." He donned a mask and black-and-white tights and had a knack for performing seamless moves.In early September, the man known for his strength felt tired and then developed a cough and fever. A few weeks later, he was having trouble breathing and was taken to the ER."He went in with pneumonia and was then diagnosed with COVID-19," said his daughter Barbara Rodriguez.Barbara says a few days later, he was placed on a ventilator. About three weeks later, Martin, a husband and father of two, died at the age of 53."He gave me strength, gave me guidance, and helped me become the person I am today. Knowing I won't have him for the future is painful," said Barbara.The man she knew as her loving, caring father stood in contrast to the character inside the ring. After several years in Mexico's famed AAA Lucha Libre in the early 90s, Rodriguez moved to San Diego and became a freelancer, wrestling in leagues in Southern California, Canada, and Mexico. He was always the bad guy and he loved it."Hyped him up even more. He loved entertaining people, making them laugh and feeling emotion," said Barbara.Since the pandemic began, his matches had been canceled. He owns a landscaping business and was taking all the COVID-19 precautions. Barbara doesn't know how he contracted the virus."I just want people to be safe. Wear a mask. I don't want this to happen to any other families," said Barbara.A GoFundMe campaign has been set up to help the family with expenses. 1675

SAN DIEGO (KGTV) - Loved ones are speaking out more than a week after a bloody melee that injured eight guards at Donovan state prison in Otay Mesa.The violence erupted two Sundays ago, around 4 p.m., inside the recreation yard. Corrections officials say there were about 20 inmates in the yard when one of them attacked a guard. His fellow guards rushed to help. In the mayhem that followed, four inmates allegedly assaulted guards. Six of the guards suffered stab wounds.Christina Armstrong's longtime boyfriend, correctional officer Malcolm Billingsley, was in the middle of it."The best way I hear him describe it is a 'melee, just chaos' ... There was so much going on, it was hard for him to pinpoint each action that was taken," said Armstrong.Corrections officials say a warning shot by one of the guards ended the altercation. As the guards were rushed to hospitals, news filtered out to loved ones."It was frightening not knowing for several hours what was going on. It was terrifying," said Armstrong.Billingsley was not stabbed, but suffered a back injury and possible nerve damage to his hand."It's hard for him to everyday things. He can't take care of our son, let alone play with him. He's in a lot of pain," said Armstrong.His fellow guard Roland Milan was stabbed in the face and suffered a brain bleed. His wife Marcy says he's had four plates inserted into his face."A stab wound to the face, to the mouth area. All his upper teeth were knocked out," she said.Sources say in all, eight guards were injured, including one with a fractured bone in his back.Armstrong says because of an ongoing investigation, she can't reveal details of the melee, but says the guards fought hard for their lives and the lives of their fellow guards."They are all heroes. Malcolm went to work that day to carry out his duty as a correctional officer an he became a victim but his strength and courage allowed him to come home a hero," said Armstrong, choking back tears.Corrections officials say the four inmates could face attempted murder charges.Gofundme campaigns have been set up for both Milan and Billingsley to help with expenses. 2147