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SAN DIEGO (KGTV) -- Dr. Scott Overcash and the staff at La Mesa-based laboratory eStudySite are preparing for what could be a history-making clinical study."I'm personally really excited about being in the effort to try to prevent people from getting the disease," said Overcash.In just days, Overcash will soon be overseeing a first-of-its-kind trial of a coronavirus vaccine created by the American biotech company Moderna.Starting as early as next week, the first of 350-500 local patients will begin receiving the vaccine.The same one has already been given to patients in phases one and two of the trial. This is the next and possibly final step before FDA approval."What's a little bit different about this particular situation is that the different phases have all been sort of compressed and are all ongoing at the same time," Overcash explained.Overall, 30,000 people around the country are expected to take part in this larger study.Unlike earlier phases, this round is targeting a more vulnerable part of the population.The patients taking part will belong to one of three groups: older than 65, younger but with underlying conditions or those at high risk of catching the virus because of their job.Moderna's vaccine uses what's called messenger RNA to trick the body's cells into producing the antibodies necessary to fight the virus.So far, this particular vaccine has shown promise, but only time will tell"There are multiple candidate vaccines that are going to be rolling out and we're just so hopeful that at least one will be effective enough to be rolled out for use," said Overcash.To learn how to participate in a clinical trial, visit https://coronaviruspreventionnetwork.org/. 1708

SAN DIEGO (KGTV) — Friday marks National Margarita Day across the country and where better to celebrate than in San Diego.San Diego is already known for its excellent Mexican cuisine, so why not couple your dish with a delicious margarita? A number of spots around town can serve as the perfect stop for a margarita to celebrate.Here's where to raise a glass in San Diego:Casa Guadalajara - 4105 Taylor St, San DiegoIf you're looking for the whole experience, dive into Casa Guadalajara. This restaurant boasts a colorfully decorated patio coupled with mariachi music, food and, of course, margaritas. El Agave Tequileria - 2304 San Diego Ave B, San DiegoBottles line the wall of this Tequileria that boasts an extensive tequila collection. Barrio Star - 2706 5th Ave., San DiegoWhy enjoy one margarita when you can get a taste of several? Barrio Star offers margarita flights in addition to a delicious roasted jalapeno blackberry version and weekly special marg.El Prez - 4190 Mission Blvd, San DiegoIf you're looking for something a little more exciting, El Prez is located in Pacific Beach and offers lots of food as well as a nice view from the rooftop patio. Old Town Tequila Factory - 2467 Juan St, San DiegoThe Tequila Factory offers an eatery with rooftop views along with, you guessed it, tequila. The restaurant even has some special edition tequila. Casa De Bandini - 1901 Calle Barcelona, CarlsbadHead to the Carlsbad/Encinitas area for some of Casa de Bandini's fruity "famous" margaritas, featuring flavors like peach, banana, cincorita, midori, and more paired with a variety of tequilas. Baja Betty's - 1421 University Ave., San DiegoHillcrest's Baja Betty's offers several different takes on the margarita, including an "iced latte," Red Bull, and ones with a collectible rubber duck included.Cantina Mayahuel - 2934 Adams Ave, San DiegoIf you're looking for more than just a great margarita, Cantina Mayaheul also has some great fish tacos in a low-key environment with a wood bar backdrop. The Blind Burro - 639 J St, San DiegoThis stylish Mexican eatery and bar is decorated in wood and serves Baja-style cuisine and has lots of cocktails to choose from.La Puerta - 560 Fourth Ave, San DiegoLa Puerta offers signature tequila alongside family recipes. If you're looking for some excitement, La Puerta also hosts DJs after dark.Puesto - 789 West Harbor Dr., San Diego; 1026 Wall St., La JollaLa Jolla and San Diego's Puesto takes fruity and spicy twists on the margarita, churning out and avocado marg, spicy variation with jalapeno, and pineapple/watermelon creations.Ponce's Mexican Restaurant - 4050 Adams Ave., San DiegoA dozen varieties of margaritas await at Ponce's, including blending together spices, sweet and sour flavors, and tequila or mezcal in delicious ways. 2802

SAN DIEGO (KGTV) — Four San Diego businesses, including two restaurants and two gyms, have filed a lawsuit seeking an emergency injunction to stop the latest shutdown orders.Under the red tier, both sectors were open for indoor operations as limited capacities. Restaurants were allowed to serve people inside at 25 percent of the normal capacity, and gyms at only 10%.On Saturday, purple tier restrictions will go into effect, meaning businesses like restaurants and gyms must shutdown indoor services completely and move outside.Cowboy Star Restaurant & Butcher Shop, Home & Away Encinitas, Fit Athletic Club, and Bear Republic filed the lawsuit against California Gov. Gavin Newson and the County of San Diego, as well as other state and county officials arguing that the closures go against their rights.The lawsuit states that Newsom and the California Department of Public Health (CDPH) lack the authority to impose the continuing restrictions on California businesses.All four businesses detail the numerous health and safety measures they’ve added to provide a safe environment for staff and customers during this pandemic.“I think it’s pretty clear that the law is on the side of governmental authority to try to get this under control,” said Jan Ronis, an attorney with the Law Offices of Ronis & Ronis. “Why they continue to file lawsuits… it’s beyond me.”Ronis is not involved in this case, but said when the pandemic began, he reviewed emergency legislation available to the government at both state and federal levels.“These laws have been in the book for decades, and governments have used them sparingly, and quite frankly think they’re valid as surprised as I was by the breadth and scope of government authority once these emergency declarations are declared,” said Ronis.He said he had seen similar lawsuits filed across the state during the last several months, and most don’t hold up in court.“I really feel sorry for the businesses, but the fact is this is a monumental health crisis,” said Ronis.Dr. Wilma Wooten, San Diego County’s public health officer, recently asked for the CDPH to allow the county to stay in the red tier. She explained that businesses that would be impacted the most by purple tier restrictions, like restaurants and gyms, are not the cause for the local increase in COVID-19 cases.The lawsuit said despite the data provided by Dr. Wooten, the CDPH still denied the request without any justification based on science or data.Both the law firm that filed the lawsuit and the County of San Diego refused to comment on this matter, stating they do not comment on pending litigation. 2646

SAN DIEGO (KGTV) -- Despite the still-high cost of living, San Diego’s housing market is beginning to cool down, according to a new report by Zillow. San Diego ranked third on the list of housing markets seeing the biggest slowdown. San Jose and San Francisco, two markets also known for their high costs of living, places first and second on the list The report shows that conditions in San Diego’s market are favoring buyers more than they did a year ago. RELATED: Home prices rise, sales plungeMore than 20 percent of homes for sale in America’s Finest City had a price cut in January of 2019, compared with only 12.4 percent of homes that saw a cut in January of 2018. Of the homes that have sold, 95.7 percent sell for their listing price. At this time last year, 97.7 percent of homes sold for their list price. The amount of time it takes to sell homes is also on the rise. In 2018, homes sold in 60 days, including time to close, Zillow reports. So far this year, homes are selling in 75 days. RELATED: Realtors expect busy spring for buyers and sellersEven though the market is starting to cool, San Diego’s median home value is 1,400. In comparison, the national median is just 5,300. “It is no surprise that the markets which pushed the bounds of affordability over the housing recovery are now experiencing significant cooling,” said Skylar Olsen, Zillow Director of Economic Research. “As down payments and mortgage payments far outpaced incomes, buyer demand eventually exhausted itself. Those buyers looking in cooling markets will likely welcome the relief, although the entry price is still high. Inventory is returning and spending more time on market, meaning their decision making can be made with a cooler head.”RELATED: How housing got so expensive 1785

SAN DIEGO (KGTV) - Doctors across San Diego shared mixed emotions of despair and hope this week, as San Diego's COVID-19 cases surge while front line workers get the first doses of a vaccine."This is actually a really difficult time right now," says Dr. Holly Yang, the President of the San Diego County Medical Society. "Our hospitals are getting quite full and staff is getting really stretched.""It's tiring," says Dr. William Tseng, an Internist at Kaiser Permanente Hospitals. "But, as health professionals, we're here to take care of patients."They say this week has been particularly hard, as an influx of people who contracted the virus during the Thanksgiving holiday threatens to overwhelm the system."It gets tough," says Dr. Karrar Ali, an Emergency Room Physician at Sharp Chula Vista. "Now we're starting to make decisions based upon capacity... That's tough, when your resources start dwindling to the point where it's not just beds, but we're having staffing issues as well."Dr. Yang says, even as bad as things look right now, with the Southern California all but out of ICU beds, doctors in the SDCMS take hope from the vaccine."There's a light at the end of the tunnel," she says. "But that tunnel is long and dark. We're going to get there, but the challenge of getting us to there through this very difficult time is going to be a hard one." 1370