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Johnson & Johnson announced it has paused its coronavirus vaccine trials on Monday following an “unexplained illness” among one of its participants.Johnson & Johnson stressed that adverse events during trials are expected, and a pause gives researchers an opportunity to review all of the medical information before moving forward with the trial. Johnson & Johnson added that it’s not always immediately known if the affected person received a placebo or a study treatment.Among the trials paused was Johnson & Johnson’s multi-country “ENSEMBLE” vaccine, which entered Phase 3 testing in September. Johnson & Johnson said last month that its goal was to seek an emergency use authorization approval in early 2021.The FDA noted that a vaccine candidate must be at least 50% effective to receive emergency use authorization. Vaccine candidates should include a median follow-up duration of at least two months after completion of the full vaccination regimen to help provide adequate information to assess a vaccine’s risk-benefit.According to the FDA, a typical Phase 3 trial would take one to three years.“NIH is committed to supporting several Phase 3 vaccine trials to increase the odds that one or more will be effective in preventing COVID-19 and put us on the road to recovery from this devastating pandemic,” said NIH Director Francis S. Collins, M.D., Ph.D. “We also know that preventing this disease could require multiple vaccines and we’re investing in those that we believe have the greatest potential for success.” 1554

Jack Hanna, a local legend who brought his passion for wildlife and people in front of televisions across the world, has announced his retirement after 42 years, the Columbus Zoo said Thursday.Jungle Jack Hanna, as he is affectionately called by his fans, will retire as the director on Dec. 31, 2020.“Out of respect for the many people whose lives the Hannas have touched, this news is being shared now to give the community ample time throughout the rest of the year to celebrate and thank Jack and Suzi,” the zoo said in a statement.Since the beginning of his career, he has transformed the role zoos play in their communities and globally. Hanna first arrived in Ohio in 1965 to attend Muskingum University. Always the animal lover, he even brought his pet donkey with him to live in the fraternity house. While at Muskingum, Jack met his wife, Suzi, and they married in 1968. 888

Judge ruled she will stay in detention where she is getting therapy ... next court date is September. Mother and daughter both visibly upset https://t.co/4VK0biBtWE— Jennifer Ann Wilson WXYZ (@JennaWils) July 20, 2020 225

Kingsley, Iowa is home to 1,400 people. “Everybody knows everybody,” said resident Chet Davis.Davis owns the town’s single grocery store: Chet’s Foods. The store has been operating for decades, and Davis’ family has owned it for more than 40 years.Generations of the community have come through these doors, but now, Davis is worried this neighborhood staple may have an expiration date.“Whether we can make it the rest of the year, I don’t know,” said the father of four and grandfather of eight.Davis said his store’s sales took a big hit when a new neighbor moved in just a few blocks away. “This year, we had a Dollar General open up in Kingsley,” he said. After the discount store opened, Davis said his profits dropped by about 20-percent.“It’s disheartening,” said Davis. “You just do what you can, and that’s all you can do, so you just gotta kind of accept it. But you don’t want to; you want to fight it.”The loss in income is something he can’t afford for long. “It costs us ,000 a month just in electricity,” said Davis, as he pointed at the cold storage inside his store that’s necessary to keep frozen products, meats and produce fresh.But Davis has a bigger worry: the loss his entire town is about to see.“If we lose our store here in town, if you want a head of lettuce, you’ll have to drive 25, 30 miles. They always talk about a food desert, and that’s what we’ll have here if we end up having to close the store like we did the other one,” said Davis, referring to his second grocery store just a few miles away.What used to be a space packed with fresh produce is now empty, collecting dust. Davis and his family were forced to close just over one year after Dollar General opened right next door.“They came in and took about 30 percent of our business right off the top. A little bit of it came back, but not enough to pay the basic bills,” said Davis.Davis’ story is a snapshot of the incredible growth of dollar stores across the United States over the last decade.There are more than 33,185 stores across the country. That’s more than all the Starbucks and McDonald’s in the U.S. combined. 2124

KANSAS CITY, Mo. — The NFL has decided to move the upcoming Kansas City Chiefs and Los Angeles Rams game from Mexico City to Los Angeles due to poor field conditions.The NFL tweeted a statement Tuesday saying that the field didn't meet standards for "playability and consistency."  304