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SAN DIEGO (KGTV) - Life is changing on Marine Corps Air Station Miramar, as dozens go into precautionary quarantine after exposure to COVID-19.The protocols you see around San Diego County are in effect on base, bringing the Health Protection Condition on base up to Level Bravo, according to Public Information Officer Capt. Matthew Gregory.The spectrum ranges from Alpha to Delta.RELATED: Third MCAS Miramar Marine tests positive for coronavirusThat means changes to daily life, starting at the gate."Our gate guards are now under a no touch ID policy, so the driver will keep hold of their ID. They'll get looked at by the MPs [Military Police] and wave them through," Capt. Gregory said.Restaurants on base are carry-out only. The chapel, tax center and gym are closed. Anyone on base who can work from home is mandated to.RELATED: Kearny Mesa hotel to be used as coronavirus quarantine site"The events around the coronavirus are unprecedented. I cannot remember in my lifetime anything that has happened on this scale," Capt. Gregory said.No tight formations, like you would see at Color Guard practice, or group meetings are allowed to comply with social distancing protocol.The base learned key practices from the CDC and Health and Human Services during the waves of Americans quarantined on base after returning from China, or a cruise. That helped them prepare for the cases they're now seeing on base.RELATED: San Diego-based Navy hospital ship to assist hospitals amid COVID-19 outbreak"We proactively set aside another barracks, cleaned it up, and that way we have a place for people who may be sick, who live on base, or require quarantine can go," Capt. Gregory said.As of Wednesday they have about 45 Marines in the building. Three tested positive for COVID-19. The others are there out of precaution after being exposed."Along with that comes plans for... having meals brought to them, laundry services, all those things, so units here on base are going to be responsible for their Marines who may be in quarantine or may be sick," he said.RELATED: San Diego and national closures, cancellations, postponements due to COVID-19Capt. Gregory said it's better to over prepare and look back thinking it was easy, than to under prepare and make things harder.He said the base is ready to take on any mission that comes their way as they continue to balance the community's needs, their Marine's needs, as well as their ability to protect. 2458

SAN DIEGO (KGTV) – Just days into California's new stay-at-home order, many businesses say this time around they won’t comply with restrictions.Some restaurant owners tell ABC 10News they’re not doing it out of defiance, but as a way to survive.“We have to stand up for ourselves. We have to open or else we lose the risk of losing our business entirely,” said Annie Rammel, the owner of Oak + Elixir restaurant in Carlsbad.Rammel said she spent ,000 to have a deck built outside of Oak + Elixir on State Street to provide a safe dining option for patrons.It was going well until she had to shut things down once again this week as COVID-19 cases surged and the state put restrictions on in-person dining were put back in place.“Closed, open, closed, open,” she said. “A lot of us are not doing well; we’re not doing well, the take out and to-go we’re losing money on that.”Rammel and a group of small business owners in Carlsbad and Oceanside decided to reopen for in-person dining Friday and take their chances, including several restaurants in the Carlsbad Village.She said if she stayed closed, her 15 employees would be laid off during an already rough year.“It’s for our employees to put food on their tables; some of them have children that they have to provide for, the holidays are coming, and I’m just not going to do that,” she said.Her patio and additional outdoor sidewalk tables were ready for customers on Friday at 4 p.m. Rammel said she expected to seat approximately 100 customers.Just next door at Caldo Pomodoro, customers were seated outside for lunch Friday.“We’re basically fighting for our lives, and we’ve been here for 29 years, it’s a family-owned and operated restaurant, it’s not that we’re doing anything wrong, we just want to survive,” said Justin Davis, who works as a server at the restaurant. “If we shut down, we’re pretty much not going to open again. We did the plexiglass, redid our tables, and invested so much money into it, and we don’t see any reason why we should shut down again.”A Carlsbad Police spokesperson said officers respond to reports of businesses operating outside of the health orders, but the goal is to gain compliance through education.However, they said willful violations witnessed by officers will be reported to the county for documentation.“We’re scared to lose our ABC license, which is our liquor license,” said Rammel. “If that happens, the group of us is saying we’re going to push through, we have some attorneys on our side, and they say we have a really good fight because there is no evidence that these spikes are coming from us.” 2614

SAN DIEGO (KGTV) — In some of the most severe cases of COVID-19, doctors are finding it’s not the coronavirus making people critically ill.It’s their own immune system, and a San Diego-based biotech company thinks it has an answer.La Jolla-based INmune Bio announced Tuesday it has FDA approval to begin a Phase 2 clinical trial on its inflammation fighting drug, Quellor.In many of the sickest COVID patients, doctors have noticed their blood is filled with high levels of immune proteins called cytokines. Cytokines act as messengers between cells and the virus can cause them to go haywire, setting off what’s known as a cytokine storm.In a cytokine storm, the body’s immune system starts to attack its own cells and tissues rather than the virus. During the Spanish Flu of 1918, many of the deaths were caused by cytokine storms.“You need to control the cytokine storm to keep patients from getting sick,” said INmune Bio’s CEO Dr. R.J. Tesi.There are several different types of cytokines. A drug undergoing testing in a federal trial with remdesivir targets a cytokine called beta interferon.The San Diego biotech’s drug Quellor suppresses a very specific cytokine called soluble tumor necrosis factor, which Dr. Tesi calls “the master cytokine” because of its role in triggering other immune proteins.Dr. Tesi said this particular cytokine may contribute to another troubling issue with COVID-19: blood clotting.“When they write the history of COVID-19, the clots are going to be the bad guy,” Dr. Tesi said. “These blood clots go off everywhere and they gum up the works. They make it so the lungs can't work. They make it so the kidneys can't work. They make it so the heart is screwed up. Make it so you have strokes.”INmune Bio, which is publicly traded but has just six full-time employees, is hoping its drug can address both the blood clots and the inflammation.The company plans to enroll 366 hospitalized COVID-19 patients for a Phase 2 trial to see if intervention with Quellor can keep people off ventilators and out of the ICU. 2053

SAN DIEGO (KGTV) - Infrastructure improvements will halt Coaster and Amtrak rail service this weekend in San Diego County.During the March 3 - 4 closures, neither Amtrak or Metrolink will be available to commuters in Oceanside, according to North County Transit District (NCTD). Connecting bus service will require an Amtrak reservation, however.There will be no connecting bus service for Coaster commuters, though passengers can use Breeze Route 101 or MTS connecting service, NCTD says.10NEWS TRAFFIC CONDITIONSCoaster and Amtrak service will be canceled on March 10 - 11 as well due to an emergency exercise. The exercise will be held at the Carlsbad Poinsettia Coaster Station from 10 a.m. to 3 p.m. Those in the immediate area should expect to see emergency vehicles.On the Friday following each closure, southbound Amtrak Rail 2 Rail trains A792 and A796, scheduled to depart Oceanside at 10:05 p.m. and 12:01 a.m., will complete their trips to Santa Fe Depot, but Amtrak train A590 will be canceled.The Monday following each closure, rail service will re-open, though trains may be delayed up to fifteen minutes.For future closure information, visit NCTD's website. 1196

SAN DIEGO (KGTV) — Mardi Gras is right around the corner, which means San Diegans are getting ready to "laissez les bons temps rouler" (let the good times roll.)Several events this weekend will kick off the local festivities in San Diego. All of it culminating on March 5, known as "Fat Tuesday,"traditionally the last day of the Carnival season.Looking for Kings Cake as well? Try out this delicious recipe from San Diego Family Magazine!Here are some great events you won't want to miss out on:San Diego Mardi Gras Fat Tuesday Celebration When: March 1 - 2, March 5 Where: Gaslamp District Cost: Starts at Mardi Gras gets started early in San Diego's Gaslamp District with 20 parties over the weekend and then for one more night on Fat Tuesday. Tickets get guests access to more than 20 nightclubs, bars, and restaurants, an opening night and finale party, and food and drink specials around downtown.Gaslamp District Mardi Gras Big Easy Bites & Booze TourWhen: March 2Where: Gaslamp DistrictCost: Starting at Enjoy a taste of San Diego and Mardi Gras with 20 Mardi-Gras inspired plates, Carnival cocktails, an exclusive after party at a secret location, and more during the Gaslamp Mardi Grass Big Easy Bites and Booze Tour through downtown.2nd annual Blvd. Mardi Gras CrawlWhen: March 3Where: El Cajon Boulevard, North ParkCost: Tickets are free for - specialsA traveling party will take over North Park's El Cajon Boulevard, bringing guests across local breweries, bars, and restaurants for drink and food specials, led by the Euphoria Brass Band along the way! The final stop will be a party at the Lafayette Hotel for music, dancing, and the best-decorated “Mardi-Bra” contest.Mardi Gras 10K & 5KWhen: March 3Where: Rancho Bernardo Community ParkCost: - Celebrate Mardi Gras and enjoy a Carnival in the park in Rancho Bernardo at the inaugural Mardi Gras 10K & 5K. Hit the scenic trails around RB in colorful Mardi Gras gear and enjoy a finish line festival!Mardi Gras Party at House of BluesWhen: March 5Where: House of Blues San DiegoCost: No cover, open to publicHouse of Blues celebrate Mardi Gras with a party at its restaurant and Voodoo Room, featuring a special food and drink menu, circus and interactie entertainment, and live music by Madame Leroux & Krewe. 17th Annual Hillcrest Mardi GrasWhen: March 5Where: Hillcrest Pride FlagCost: - Hillcrest will host a neighborhood-wide party crawl through the area's best bars, clubs, and music venues. Themed party stops will greet guests with drink deals, collectible beads, giveaways, and live entertainment! 2613