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Lindsey Vonn had barely finished her first race at PyeongChang 2018 when the online abuse resumed.One of the most successful female ski racers of all time, Vonn had received comments in December from some people saying they hoped she'd break her neck after she told CNN in an interview she wouldn't visit the White House should she win a medal at the Winter Olympics."Well I hope to represent the people of the United States, not the president," the 33-year-old American had told CNN's Alpine Edge late last year. 521
LAKESIDE, Calif. (KGTV) — A family is grief stricken after their elderly mother's wedding ring vanished last weekend.Daughter Leanne Farrell said she took her dad to urgent care Friday and then went to work. A nurse who cares for her parents noticed Saturday the ring was missing."There were about 4 people in and out [when] the ring disappeared and it wasn't easy to get off," she said.She doesn't believe her mother lost her ring. She said it's been on her hand for 61 years, only removed from her finger for a repair or the rare cleaning.She said they tore the house apart searching for the ring and found nothing."I can't be here 24/7 for them you know? Because I have to work and you hope the people that come in to care for them, care for them like you would," she said wiping away tears.The ring went missing just a day after her parent's 61st wedding anniversary. Her father, Ken Clody's, leg was amputated after a fall two years ago and recently had to change the hours caregivers come and go to ensure he and his wife are taken care of. He also suffers Primary Lateral Sclerosis, making it hard to communicate.Farrell explained her mother has dementia and sleeps most of the day, "she can't explain anything, she can't explain who took it, when they took it, because you can see she's not with us really much anymore."Her father said he bought the ring for 0, in 1957.Farrell described the ring as two white gold bands soldered together with three diamonds, the center just larger than the others. Farrell said it's not the price they're upset by, but the sentimental value."Oh I just hope they put it in an envelope and mail it back, the money doesn't matter just the ring," she said crying.The San Diego County Sheriff's Department is investigating the loss. They have a detective on the case interviewing the caregivers who were in the home at the time the ring went missing. 10News spoke with the care-giving company who said they interviewed their employees and said those employees hadn't seen the ring.10News did not name the company as law enforcement said they are not suspected of any wrongdoing. Clody said via email several other items went missing during the same time period, but that they were easily replaceable. The health care company called 10News late Thursday saying a couple of their employees said Mrs. Clody would take the ring off and play with it and leave it places. 2414
Last year's seasonal flu vaccine effectiveness was just 42%, the US Centers for Disease Control and Prevention estimated. Even if vaccinated, then, people had inadequate protection against the flu.This limited effectiveness was due to a mutation that occurred in the influenza A (H3N2) vaccine strain, according to a new study published Monday in the journal Proceedings of the National Academy of Sciences. This vaccine mutation resulted from an egg-based manufacturing process commonly used today.This year's flu vaccine may also be imperfect, said Scott Hensley, author of the new study and an associate professor at the University of Pennsylvania. Add to that, he said, "this could end up being a pretty bad flu season."Still, he said, "our best protection" against severe illness is getting vaccinated with the flu shot we have today.Finding answersEach year before flu season begins, a vaccine is made based on whichever virus strains are expected to circulate. The selected seed strains are distributed to vaccine manufacturers which then produce their formulations and make them available to health care professionals before the season begins.During the 2015-16 season, vaccine effectiveness was 47%, while for the previous 2014-15 season, effectiveness was just 19%, according to the CDC. While the overall effectiveness of last season's vaccine was 42%, it was only 34% effective against the H3N2 viruses that dominated the season.Vaccine effectiveness varies based on how well it matches the circulating virus strains. Sometimes, a vaccine corresponds to the predominant virus yet its effectiveness is still not what scientists would expect. Trying to understand which element of the vaccine failed is difficult.Hensley and his team began their investigation of last year's vaccine by looking at the seed strains that had been distributed to vaccine manufacturers. These seed strains had been propagated in chicken eggs, the common method used today."The sequences of these viruses are available and when we did an alignment to see what the sequence of these vaccines were compared to the viruses that were circulating, it became very obvious that there was this mutation," said Hensley.To see the effects of the mutation, the team next looked at how the immune systems of both animals and humans who'd been inoculated with an egg-based flu vaccine responded to the actual circulating viruses.The antibodies -- immune system proteins that fight invading pathogens -- elicited in both animals and humans failed to bind to and neutralize the flu viruses, Hensley and his colleagues found.While most vaccines in the United States are made in chicken eggs, a small fraction are produced in insects or mammalian cells, Hensley explained. (These are given to people with egg allergies.) He and his team compared immune responses in animals and humans who had received a cell-based vaccine -- in this case, Flublok made by Protein Sciences Corporation."And we found both animals and humans receiving that (cell-based) vaccine had superior antibody responses that could bind and neutralize these circulating H3N2 strains," said Hensley.Making a better vaccine"Most of the infrastructure to produce vaccines in the US is based on chicken eggs," said Hensley. There are good reasons for this, including the fact that egg-based propagation allows manufacturers to quickly produce large quantities of vaccine.While egg adaptations have always been a problem, beginning last year it had become a "huge problem," said Hensley. "As soon as you try to grow this virus in eggs, within a few hours, the virus will acquire this kind of mutation."This is not an easy problem to fix, he said. To produce vaccines in cells means "a very expensive process for companies to just change their overall manufacturing process," Hensley explained. "You can't really do that on the drop of a dime."Meanwhile, the same seed strains used last year are being used this year to make the current vaccine, said Hensley."This year may be especially difficult because, in addition to this egg adaptive mutation which was present last year, there's indication that the H3N2 viruses are actually evolving," said Hensley.Not only will the vaccine be a mismatch with the actual circulating viruses due to egg adaptation but the vaccine could also be a mismatch due to unexpected viral evolution.What kind of flu season is ahead?It's too early to speculate which viruses will become dominant in the United States over the course of the coming flu season, said Hensley, "but it's starting to look like it will be H3 viruses." H3 viruses are influenza A viruses."There are the A group of viruses and the B groups," said Dr. William Schaffner, an infectious disease specialist at Vanderbilt University. "The A groups are the ones that usually are responsible for large epidemics ... whereas the B flu strains usually smolder along. They always cause illness -- it can be just as severe as the A strains -- but they don't produce large outbreaks."Though last year's vaccine was mostly ineffective in thwarting the flu, it still prevented nearly 30% of hospitalizations that might have resulted, according to CDC calculations. For older adults, that rate was even higher, at 37%. Plus, the vaccine reduced outpatient visits by 42% last season.The CDC advises everyone 6 months and older to get a flu shot, as only injectable flu vaccines are recommended. More than 130 million doses of flu vaccine have been distributed so far this year and flu activity is still low across the nation.It's still early days, but experts believe we may be facing a tough season, and not only because of vaccine concerns.The reason?Australia had a tough flu season this year, with a total of 215,280 laboratory-confirmed cases and 504 flu-associated deaths reported to its National Notifiable Diseases Surveillance System as of October 13, government data show. According to a surveillance system report, adults over the age of 80 and children between 5 and 9 years old have been most affected."In general, we get in our season what the Southern Hemisphere got in the season immediately preceding us," Dr. Anthony Fauci, director of the United States' National Institute of Allergy and Infectious Diseases, said in an interview last month.An "intelligent guess," therefore, is that the Northern Hemisphere, like the Southern Hemisphere, will likely battle more cases of the viral infection, he said, though "with influenza, it is never 100%.""If H3N2 viruses dominate the US flu season again this year, vaccine effectiveness will likely be moderate to low again," said Hensley.Still, he said, everyone should get their annual flu shot."The other components of the vaccine, like H1N1 and influenza B, will likely provide excellent protection," said Hensley. "The vaccine will also likely prevent severe disease and death caused by H3N2 viruses, even though this component of the vaccine is mismatched." 6969
LANCASTER, Calif. – A man has been arrested for the murders of his 12-year-old son and 13-year-old daughter in Lancaster, California, which is north of Los Angeles.The L.A. County Sheriff’s Department said in a statement that fire personnel located the victims when they were called to the family's home to investigate a possible gas leak Friday morning.Detectives say the children both appeared to have suffered from lacerations and stab wounds.The mayor of Lancaster, Rex Parris, confirmed to KABC and the L.A. Times that the children were both found decapitated. He told the newspaper that “it was pretty brutal.”Officials tell the L.A. Times that the victims were found in separate bedrooms in the home and it’s unclear how long they had been dead.At the home, the sheriff’s department says there were also two adults and two other children who were questioned by homicide investigators. The L.A. Times identified the two adults as the victims’ parents.The children's father, Maurice Taylor Sr., was later arrested on murder charges and booked into jail, where he’s being held with a million bail.The L.A. Times reports the suspect is a personal trainer who acquaintances described as being “mellow” and “reliable.”Detectives say they’re continuing to investigate the murders. Anyone with information about incident is asked to contact the sheriff’s department’s homicide bureau at (323) 890-5500. If you prefer to provide information anonymously, you may call Crime Stoppers by dialing (800) 222-TIPS (8477). 1524
Las Vegas mass shooter Stephen C. Paddock, a high-stakes gambler who once boasted of wagering as much as million in a single night, had "lost a significant amount of wealth" in the two years prior to last month's massacre, the city's sheriff said in a recent interview.Sheriff Joseph Lombardo described Paddock as a narcissist and "status-driven" and said his financial decline "may have a determining effect on why he decided to do what he did."Lombardo's statements, made during a wide-ranging interview with CNN affiliate KLAS, are the closest a law enforcement official has come to articulating a possible motive in the October 1 attack in which at least 58 people were killed and more than 500 were wounded. 723