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Pfizer announced Monday that its COVID-19 vaccine candidate has been 90% effective.In a press release, the company said that in Phase 3 trials, the vaccine has proven to promote a vaccine efficacy rate above 90% following the two-shot regimen.The Associated Press said that while Pfizer's announcement means the company is on track to file an application for emergency use authorization later this month, it does not mean a vaccine is "imminent" and more studies are needed.Pfizer's vaccine candidate began Phase 3 testing in the summer and is among a handful of vaccine candidates that could be distributed in the coming months pending FDA approval.Phase 3 trials consist of testing about 30,000 voluntary participants in a double-blind study — meaning half of those participating receive the vaccine, and half receive a placebo. Pfizer's vaccine requires two shots, which need to be taken 28 days apart.According to Pfizer, 90% of those who were tested for the vaccine had developed protection against the virus seven days following the second shot.Pfizer is already in the process of producing millions of doses of its vaccine candidate after the U.S. government agreed to pay .95 billion for 100 million doses of the vaccine, should it prove effective. If and when the FDA grants approval for the vaccine, it will be distributed to hospitals around the country by the U.S. military in an effort the Trump administration has dubbed "Operation Warp Speed.Even though hundreds of thousands of doses of the Pfizer vaccine will be ready for shipment if it is approved for emergency use, it will need to be rationed in the first months of its availability. According to a playbook for "Operation Warp Speed," essential health care workers and people in high-risk populations would have the first opportunity to get a COVID-19 vaccine. The rest of the general public will be able to get the vaccine as more doses become available later in 2021.Pfizer was one of a handful of companies that pledged in September not to distribute their vaccine under political pressure, and would only do so if it proved to be effective in large scale trials.Monday's announcement sent stock market futures through the roof, as investors eyed a return to economic normalcy should Pfizer's vaccine be given emergency approval in the coming days or weeks.President Donald Trump also celebrated the announcement in a tweet on Monday morning."STOCK MARKET UP BIG, VACCINE COMING SOON. REPORT 90% EFFECTIVE. SUCH GREAT NEWS!" Trump tweeted. 2524

OWEGO, N.Y. — A New York police officer is being hailed a hero after he saved the life of a man trapped for 10 hours in a car with no heat that was buried in snow.According to New York State Police, 58-year-old Kevin Kresen was driving during Wednesday's snowstorm when he ran his car off the road. A short time later, Kresen became trapped when a snowplow covered his car with four feet of snow. 404

PAHOA, Hawaii (AP) — Lava creeping across roadways destroyed four homes and left dozens of others in the shadow of Hawaii's Kilauea volcano isolated Saturday, forcing more residents to plan for a possible evacuation.Hawaii County Civil Defense said a fissure near the neighborhood of Lanipuna Gardens has been continuously erupting, releasing a slow-moving lava flow. If that lava threatens a nearby highway, more people will be told to prepare for voluntary evacuation.On Friday, fast-moving lava crossed a road and isolated about 40 homes in a rural subdivision, forcing at least four people to be evacuated by county and National Guard helicopters.RELATED: San Diegans working with Red Cross in HawaiiPolice, firefighters and National Guard troops were securing the area of the Big Island and stopping people from entering, Hawaii County Civil Defense reported. The homes were isolated in the area east of Lanipuna Gardens and Leilani Estates. Both neighborhoods had 40 structures, including 26 homes, decimated by lava over the past two weeks.Officials said three people were still in that area but not in imminent danger. They were advised to shelter in place and await rescue by helicopter first thing Saturday.County officials have been encouraging residents in the district to prepare for potential evacuations.RELATED: Golfers continue playing as ash cloud grows in HawaiiEdwin Montoya, who lives with his daughter on her farm near the site where lava crossed the road and cut off access, said he was at the property earlier in the day to get valuables."I think I'm lucky because we went there this morning and we got all the batteries out, and all the solar panels out, about ,000 worth of equipment," he said. "They have to evacuate the people that are trapped up there right now in the same place that we were taking pictures this morning."He said no one was on his property, but his neighbor had someone on his land."I know that the farm right next to my farm . he's got somebody there taking care of the premises, I know he's trapped," Montoya said.Montoya said the fissure that poured lava across the road opened and grew quickly."It was just a little crack in the ground, with a little lava coming out," he said. "Now it's a big crater that opened up where the small little crack in the ground was."Experts are uncertain about when the volcano will calm down.The Big Island volcano released a small explosion at its summit just before midnight Saturday, sending an ash cloud 10,000 feet (3,048 meters) into the sky. The U.S. Geological Survey's Hawaiian Volcano Observatory said eruptions that create even minor amounts of ashfall could occur at any time.This follows the more explosive eruption Thursday, which emitted ash and rocks thousands of feet into the sky. No one was injured and there were no reports of damaged property.Scientists said the eruption was the most powerful in recent days, though it probably lasted only a few minutes.It came two weeks after the volcano began sending lava flows into neighborhoods 25 miles (40 kilometers) to the east of the summit.A new lava vent — the 22nd such fissure — was reported Friday by county civil defense officials.Several open fissure vents are still producing lava splatter and flow in evacuated areas. Gas is also pouring from the vents, cloaking homes and trees in smoke.The fresher, hotter magma will allow faster lava flows that can potentially cover more area, said Janet Babb, a geologist with the Hawaiian Volcano Observatory.Much of the lava that has emerged so far may have been underground for decades, perhaps since a 1955 eruption.Meanwhile, more explosive eruptions from the summit are possible."We have no way of knowing whether this is really the beginning or toward the end of this eruption," said Tom Shea, a volcanologist at the University of Hawaii. "We're kind of all right now in this world of uncertainty."It's nearly impossible to determine when a volcano will stop erupting, "because the processes driving that fall below the surface and we can't see them." said volcanologist Janine Krippner of Concord University in West Virginia.U.S. government scientists, however, are trying to pin down those signals "so we have a little better warning," said Wendy Stovall, a volcanologist with the observatory.Thus far, Krippner noted, authorities have been able to forecast volcanic activity early enough to usher people to safety.The greatest ongoing hazard stems from the lava flows and the hot, toxic gases spewing from open fissure vents close to homes and critical infrastructure, said Charles Mandeville of the U.S. Geological Survey's volcano hazards program.Authorities have been measuring gases, including sulfur dioxide, rising in little puffs from open vents.The area affected by lava and ash is small compared to the Big Island, which is about 4,000 square miles. Most of the island and the rest of the Hawaiian chain is unaffected by the volcanic activity on Kilauea.State and local officials have been reminding tourists that flights in and out of the entire state, including the Big Island, have not been impacted. Even on the Big Island, most tourist activities are still available and businesses are open.___Associated Press journalists Jae Hong and Marco Garcia in Pahoa, Sophia Yan, Jennifer Kelleher and Audrey McAvoy in Honolulu, Becky Bohrer in Juneau, Alaska, Seth Borenstein in Washington, D.C., and Alina Hartounian in Phoenix contributed to this report. 5478

Outdoor equipment retailer REI announced they are looking to sell their brand new corporate headquarters in Washington, as they embrace working from home and remote work options.“The dramatic events of 2020 have challenged us to reexamine and rethink every aspect of our business and many of the assumptions of the past. That includes where and how we work,” said REI President and CEO Eric Artz, in a video call with employees Wednesday. “As a result, our new experience of 'headquarters' will be very different than the one we imagined more than four years ago.”The company’s headquarters is being built in the Seattle area, in Bellevue, and is roughly 400,000 square feet and sits on eight acres of land. Corporate staff was planning on moving in to the newly-completed building this summer, according to the Seattle Times. REI transitioned to nearly 100 percent remote work in early March for corporate staff. Washington reported some of the earliest cases of coronavirus in the country.Retail stores closed in March across the country and recently reopened.The company admits the sale will also benefit them financially. They cite safety and preventative measures retail stores and the company have taken during the pandemic, in addition to slower sales with the temporary closure of stores.Artz and the board of directors have taken paycuts and in July, REI announced a 5 percent reduction in staff.REI says they will embrace remote work as an “engrained, supported, and normalized model for headquarters employees, offering flexibility for more employees to live and work outside of the Puget Sound region and shrinking the co-op’s carbon footprint.” 1665

PARKER, Colo. — When 22-year-old Hannah McNeill went to sleep one night in August earlier this year, she had no idea her life was going to be dramatically altered. She woke up, couldn't move her legs and eventually was diagnosed with a rare polio-like disease that is now on the rise in Colorado."You never think it would happen to you so you don't prepare for it," she told KMGH. Acute flaccid myelitis is a spinal disease caused by a form of enterovirus. It's extremely rare and usually impacts children, causing loss of feeling and use of the arms or legs. It can leave children with permanent paralysis. "I was trying to move my toes and my feet and nothing would happen," she explained. "I knew what I wanted to do but I couldn’t pull my leg up, couldn’t take a step."Health officials report 14 cases in Colorado so far in 2018. The Colorado Department of Public Health and Environment said of those cases 11 people tested positive for enterovirus A71, one tested positive for enterovirus D68 and two people tested negative for any type of enterovirus."While all the patients were hospitalized, nearly all have fully recovered. There have been no deaths," CDPHE's Shannon Barbare said in a statement. But McNeill still hasn't fully recovered. "I still don't have all my leg strength which is why I'm in a wheelchair," she said."There is no vaccination or specific treatment for enteroviruses. People with mild illness typically need treatment only for symptoms," Barbare said in a statement. "However, some illnesses caused by EV-A71 and EV-D68 can be severe enough to require hospitalization."Colorado has previously had outbreaks of the less-common enterovirus types. Enterovirus D68 sickened 11 people with AFM. Enterovirus A71 caused similar epidemics to this year's in 2003 and 2005, the CDPHE said.The CDC has a web page devoted to AFM. It says that most patients afflicted by the disease are children and that scientists have not yet determined a single pathogen detected in patients’ spinal fluid that causes AFM.But in McNeill's case, she said she's not done getting back to her normal life. She goes to physical therapy three times a week and has been making progress in the weeks since she was released from the hospital. "Two months ago I couldn’t walk, now I can in my walker," she said. "I have to get on my feet. I have a horse to ride. I have hair to do. I have so much life to live so this isn't gonna stop me now." 2545