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SANTO DOMINGO, Sept. 30 (Xinhua) -- Haitian health authorities on Friday said the number of deaths caused by cholera increased to 6,435 in the Caribbean country since October 2010.The Haitian Health Ministry said the number of people infected with cholera almost reached half a million, although the ministry repeated the epidemic was decreasing.The report said 455,727 people had been treated due to cholera, and 242,205 had to be hospitalized.The western province of Artibonite suffered the plague most with 1,196 deaths. The southwest province of Nippes registered the smallest death toll of 181.Meanwhile, in the Haitian capital Port-au-Prince, 221 people have been killed since October 2010 when the epidemic first broke out in central Haiti.The epidemic is supposedly due to the spill of dregs from a Nepalese camp, which is part of the UN Stabilization Mission in Haiti (MINUSTAH).The Dominican Republic, a country neighboring the island country Haiti to the east, has also been suffering the disease since November 2010, which has killed at least 135 people there.

BEIJING, Sept. 30 (Xinhuanet) -- The number of children being prescribed stimulants to treat attention deficit hyperactivity disorder (ADHD) has been steadily rising in the U.S. since 1996, researchers found.The finding was contained in a report released Wednesday in the U.S. medical journal Psychiatry.About 7.8 percent of children aged 4 to 17 in 2003 were diagnosed with ADHD, compared to 9.5 percent in 2007, according to the data gathered from the Health Resources and Services Administration's National Survey of Children's Health.And compared to 0.6 percent in 1987, 2.9 percent of children under 19 in 2002 have been prescribed stimulants, the report said.The finding raises the researchers' concern as stimulants have side effects such as decreased appetite, leeplessness and even heart-related damage, the report warned."Stimulant medications work well to control ADHD symptoms, but they are only one method of treatment for the condition. Experts estimate that about 60 percent of children with ADHD are treated with medication." says researcher Benedetto Vitiello, MD, of the U.S. National Institute of Mental Health."There is ongoing concern that these drugs may not be used properly, especially when they are prescribed to college students or children in their late adolescence who are more in charge of their care and may not be using the medications as prescribed." he added.

SAN FRANCISCO, Oct. 10 (Xinhua) -- Apple announced on Monday that pre-orders of its iPhone 4S have topped 1 million in a single day, surpassing the previous single-day pre-order record of the company's smartphone.The iPhone 4S pre-orders surpassed 1 million in the first 24 hours and the previous single day pre-order record held by iPhone 4 is 600,000, according to Apple."We are blown away with the incredible customer response to iPhone 4S," Philip Schiller, Apple's senior vice president of worldwide product marketing, said in a statement."The first day pre-orders for iPhone 4S have been the most for any new product that Apple has ever launched and we are thrilled that customers love iPhone 4S as much as we do," he added.U.S., newly installed Chief Executive Officer Tim Cook takes stage to give a general introduction of Apple's products, Oct. 4, 2011. Apple Inc. last Tuesday unveils iPhone 4S, the much-anticipated latest generation of iPhone.The iPhone 4S, which looks the same as the iPhone 4 but has major hardware upgrade inside, is available for pre-order last Friday and set to first arrive in stores in the United States this Friday.So far, iPhone 4, which, according to Apple, has been sold more than the first three generations of iPhones combined, is Apple's best selling iPhone.The pre-order numbers are good news for Apple as the initial introduction of iPhone 4S last Tuesday has not lived up to the anticipation of some investors and analysts, and spurred a new wave of concerns about whether the company could keep its innovation momentum in the wake of the passing of its co-founder Steve Jobs last Wednesday.

WASHINGTON, Oct. 9 (Xinhua) -- U.S. researchers have found a way to block, in an animal model, the damaging inflammation that contributes to many disease conditions. In their report receiving early online publication Sunday in Nature Biotechnology, researchers describe using small interfering RNA technology to silence the biochemical signals that attract a particular group of inflammatory cells to areas of tissue damage."The white blood cells known as monocytes play a critical role in the early stages of the immune response," says Matthias Nahrendorf, of the Massachusetts General Hospital (MGH) Center for Systems Biology, the paper's senior author. "We now know there are two subsets of monocytes -- an inflammatory subset that defends against pathogens and a reparative subset that supports healing. But if the inflammatory response is excessive, it can block the healing process and exacerbate conditions such as heart disease and cancer."Cells damaged by injury or disease release a cocktail of chemicals called cytokines that attract immune cells to the site of the damage. Inflammatory monocytes are guided to sites of tissue injury by a receptor protein called CCR2, and the MGH-led team devised a strategy targeting that molecule to block the inflammatory process but not the action of the reparative monocytes.Small interfering RNA (siRNA) technology prevents production of specific proteins by binding to associated messenger RNA molecules and preventing their translation. However, the technique requires extreme precision in developing the right siRNA molecule and delivering it to the correct cellular location.To make sure that their siRNA preparation targeted the right monocytes, researchers first confirmed that its use reduced levels of CCR2 in monocytes and increased levels of the fragments produced when siRNA binds to its target. They then showed that monocytes from mice treated with the siRNA preparation were unable to migrate towards CCR2's usual molecular target. Experiments in animal models of several important diseases showed that the siRNA preparation reduced the amount of cardiac muscle damaged by a heart attack, reduced the size and the number of inflammatory cells in atherosclerotic plaques and in lymphomas, and improved the survival of transplanted pancreatic islets."These inflammatory monocytes are involved in almost every major disease," Nahrendorf explains. "Anti-inflammatory drugs currently on the market hit every inflammatory cell in the body, which can produce unwanted side effects. This new siRNA treatment doesn't affect inflammatory cells that don't rely on the CCR2 receptor. That makes a big difference."

BEIJING, Nov. 22 (Xinhuanet) -- Global AIDS deaths and new HIV infections have each dropped 21 percent since the peak of the AIDS pandemic in 1997, according to a UN report released Monday.One major factor responsible for the result is that life-saving HIV treatments have become more popular and got to 1.35 million more people in 2010 than in 2009.In middle-income and underdeveloped nations, these treatments have saved 2.5 million lives since 1995."We have seen a massive scale-up in access to HIV treatment, which has had a dramatic effect on the lives of people everywhere," said Michel Sidibe, executive director of the U.N. AIDS program.However, 53 percent of people who need HIV/AIDS treatments -- about 7.6 million people -- cannot get them, which accounted for 1.8 million AIDS deaths in 2010.There are now 34 million people living with HIV. And just in last year there were 2.7 million new infections.The decline in deaths and new infections means the AIDS pandemic is at a turning point, the UNAIDS report argues, adding smart investment can save millions of future deaths.