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CAMBRIDGE, Mass. – The U.S. government will pay Moderna Inc. up to .525 billion to secure 100 million doses of the company’s COVID-19 vaccine candidate.The U.S. Department of Health and Human Services (HHS) and Department of Defense (DoD) made the announcement Tuesday.HHS says Moderna will manufacture the vaccine doses while clinical trials are still underway to expedite the traditional development timeline and get vaccines to the public as soon as possible.The Trump administration hopes to deliver the vaccines by the end of the year, so long as the U.S. Food and Drug Administration (FDA) authorizes their use.“In creating a vaccine portfolio for Operation Warp Speed, the Trump Administration is increasing the likelihood that the United States will have at least one safe, effective vaccine by 2021,” said HHS Secretary Alex Azar. “Today’s investment represents the next step in supporting this vaccine candidate all the way from early development by Moderna and the National Institutes of Health, through clinical trials, and now large-scale manufacturing, with the potential to bring hundreds of millions of safe and effective doses to the American people.”HHS says the vaccine doses will be delivered to government-designated locations across the country and the U.S. could acquire up to an additional 400 million doses of the vaccine.If viable, the vaccines would be available to the American people at no cost, according to HHS. Healthcare professionals could charge for the cost of administering the vaccine, though.The vaccine, called mRNA-1273, has been co-developed by Moderna and scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The third phase of the vaccine trial, which began July 27, is the first government-funded Phase 3 clinical trial for a COVID-19 vaccine in the nation, according to HHS.“We appreciate the confidence of the U.S. government in our mRNA vaccine platform and the continued support,” said Stéphane Bancel, Moderna’s Chief Executive Officer. “We are advancing the clinical development of mRNA-1273 with the ongoing Phase 3 study being conducted in collaboration with NIAID and BARDA. In parallel, we are scaling up our manufacturing capability with our strategic partners, Lonza, Catalent and Rovi, to address this global health emergency with a safe and effective vaccine.” 2402

CHICAGO, Ill. – A study published this month suggests that by lessening the amount of virus you take in by putting on a mask, you may also lessen the likelihood of getting severely sick if you contract COVID-19.As the race to a safe and effective coronavirus vaccine heats up, new research about masks is changing the narrative on their importance.Last week, CDC Director Dr. Robert Redfield called face masks the most “powerful public health tool we have.”“I might even go so far as to say that this face mask is more guaranteed to protect me against COVID than when I take a COVID vaccine,” said Dr. Redfield.It was a stark change from CDC messaging early on in the pandemic that face coverings would most likely only protect those around you.“That was because there was a lot of data at that time that you can shed the virus at high rates from your nose and mouth even when you feel well,” said Dr. Monica Gandhi, an infectious disease doctor and professor of medicine at the University of California – San Francisco.She co-authored newly published research in the New England Journal of Medicine that theorizes that not only do masks protect the wearer but they may even reduce the severity of the coronavirus when someone gets infected.“We realized that we should be messaging more strongly masks protect you as the wearer and protects others,” said Dr. Gandhi.It theoretically works much like the early days of vaccines that used small amounts of viruses to illicit an immune response in the body. So, by wearing a mask, you are only exposed to lesser amounts of the virus, if any, potentially building up a sort of immunity.“The more virus you get inside, the sicker you are, the less virus you have, the less sick you are. This is called a dose response and it's true of many infections,” said Dr. Emily Landon, an epidemiologist and infectious disease specialist at University of Chicago Medicine.Gandhi says the theory has already been studied and proven in animals.“There was a hamster study that looked at the COVID-19 virus and the more that the hamsters were given, the more sick they got,” she said.Dr. Gandhi says it could also explain the why according to the CDC, 40% of coronavirus patients are asymptomatic.“Countries that mask well have lower rates of severe illness than countries that don't mask well. So, putting it all together, this is our hypothesis.”And while the research is still theoretical, if it bears out, experts say universal mask-wearing could drive up the proportion of people who get less sick from the virus if they do contract it. 2579

CARLSBAD, Calif. (KGTV) — North County's new foodie destination is finally opening its doors for business.Carlsbad's Windmill Food Hall began taking orders during its soft opening this month, after its opening was pushed back from an expected summer debut.Diners will have their choice of several cuisines at the North County stop, from waffles to gourmet sliders to New England-style lobster rolls to Korean fried chicken.RELATED: Hot chicken to bao: Six new flavors move into Liberty Public MarketRestaurants include:Bing Haus - Asian-inspired dessert spot serving cult followed rolled ice cream such as Green Tea, Banana, and Black Sesame;Bread and Cheese Eatery - Gourmet made-from-scratch grilled cheese sandwiches stuffed with gourmet cheeses, meats, and specialty ingredients; will also be serving pineapple smoothies served inside fresh pineapples;Cross Street Chicken & Beer - Korean-style fried chicken with a popular brick & mortar on Convoy Street;(Not open yet) District 1 Pho - Vietnamese cuisine like Bánh mì sandwiches, Shaking Beef - Bò lúc l?c, and a variety of spring rolls;(Not open yet) Dough Balls - Wood-fired pizzas ranging from basic cheese or tomato basil to the meat-packed "porky" or "stinky" brussel sprouts and prosciutto — made in about 90 seconds;El Puerto Street Tacos - Burritos and tacos for breakfast or dinner and a variety of quesadilla, nacho, and seafood eats;Friend's House - Dumplings spot with hot or cold Bi Bim Bap, kim chi, Korean BBQ beef, and fish cakes; The Fry Fix - French fires in several variations like truffle, bacon, or house aioli, or loaded with steak, pesto, or poutine;Mesteeso Coffee - Variety of signature drinks like Cha Mate or Latte Mossa, and espressos, with an assortment of daily pastries and Brazilian eats;Notorious Sliders and Salads - Handcrafted burgers like the "Capone" with a fried egg and avocado mash or the "Notorious" with bacon and grilled onions;The Poke Stand - Poke rolls (burrito-style) from vegetarian to "Kalifornia" (with crab) to surf and turf with Korean short ribs;Lobster West - New England style staple foods such as Main lobster rolls made with sustainable ingredients;(Not open yet) RG's Sizzling Steer - BBQ concept from Murrieta known for delicious pulled pork, country fried steak, and tri-tip sandwiches and burgers;Thai Style Kitchen - Traditional Thai cuisine served from a traveling pop-up food stand.While plans for a speakeasy on the second floor have been scrapped, 2,000-square-feet of outdoor seating with games and picnic tables and a concept dubbed "The Library" are still planned.Carlsbad's food hall is North County San Diego's first food hall, joining other local stops like Little Italy Food Hall, Liberty Public Market, and soon, Park Commons in Sorrento Valley. Poway also has plans for its own food hall called Outpost.The 12,000-square-foot hall transforms the iconic windmill building, which was formerly a T.G.I.Fridays and prior to that, a Pea Soup Andersen’s location. 3001

CAMPO, Calif. (KGTV) - A border watch group says there are glaring holes along the border that can be plugged with the help of troops.The Department of Defense sent thousands of troops across the border to areas like the San Ysidro Port of Entry. “I don’t know all the intelligence, but it seems like (the troops) are all in the areas where the fence is pretty secure,” said Dan Russell with the Minutemen. The Minutemen is a citizen’s group dedicated to watching the border for illegal crossings. If they see any, they report them to border patrol. “Maybe they’re expecting thousands to show up in Tijuana or Tecate, but if they’re there in large numbers all they have to do is get on a bus, take the highway, drive an hour, and come over a wide open border,” Russell said.Russell says his group volunteers to watch the mile of the border just southwest of Campo. In that mile stretch, there are about five gaps along the border wall.“About every quarter mile, you’d want some eyes on the border,” he said. 1045

CALEXICO, Calif. (KGTV) -- U.S. Border Patrol agents arrested an El Salvadoran citizen Wednesday they say is a previously deported sex trafficker.Agents say Gloria Reyes-Lopez, 62, (pictured below) was arrested after Border Patrol agents noticed her illegally enter the United States at the El Centro sector around 7:30 Wednesday night.After her arrest, Reyes-Lopez was taken to the Calexico station for processing.“This individual is a convicted felon who preyed on young, innocent children,” said Assistant Chief Patrol Agent David S. Kim. “The men and women of the U.S. Border Patrol are this country’s first line of defense against threats like this.”Reyes-Lopez will be prosecuted for re-entry after removal, according to authorities. 752