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LOS ANGELES, July 18 (Xinhua) -- At least 70 genetic mutations may be involved in the formation of colon cancer, far more than scientists previously thought, a new study suggests.The study by researchers at University of Texas (UT) Southwestern Medical Center contradicts previous thinking that only a few mutated genes may play a role in the development of colon cancer."The ways we've been treating patients up to now is to just go after one target when we should be going after three to four different pathways simultaneously," said Dr. Jerry W. Shay, vice chairman and professor of cell biology at UT Southwestern.The new study identified 65 candidate genes and at least five passenger genes whose mutations play significant roles in cancer development. Inactivating the function of any of these tumor- suppressing genes led to a key step in cancer development called anchorage-independent growth, meaning cells piled up on top of each other rather than aligning neatly.According to previous studies, there were 151 candidate genes and that mutations in just eight to 15 of them would lead to cancer. There were 700 other genes classified as passenger genes whose mutations were incidental to cancer growth.Current cancer treatments target just one or two known cancer- driver genes. While patients may get transient tumor burden reduction, almost universally tumor growth returns."Those numbers are dead wrong," Dr. Shay said, suggesting a new approach to colon cancer treatments targeting multiple genes and pathways simultaneously.The next step is further research to classify more accurately which genes drive cancer and which are merely passengers, the researchers said.Study findings were published in the July 2011 Cancer Research (Priority Reports).

LOS ANGELES, June 10 (Xinhua) -- The Aquarius/SAC-D observatory, NASA's first ever satellite to study the saltiness of Earth's oceans, is in excellent health after its launch early Friday, initial telemetry reports showed.The observatory rocketed into space from Vandenberg Air Force Base in California atop a United Launch Alliance Delta II rocket at 7:20:13 a.m. PDT (10:20:13 a.m. EDT).Less than 57 minutes later, the observatory separated from the rocket's second stage and began activation procedures, establishing communications with ground controllers and unfurling its solar arrays, NASA's Jet Propulsion Laboratory (JPL) said.During the next 25 days, the Aquarius/SAC-D service platform will be tested and maneuvered into its final operational, near-polar orbit 408 miles (657 kilometers) above Earth. Science operations will begin after the observatory's instruments are checked out. This commissioning phase may last up to 65 days, JPL said.Aquarius will map the global open ocean once every seven days for at least three years with a resolution of 93 miles (150 kilometers). The maps will show how ocean surface salinity changes each month, season and year. Scientists expect to release preliminary salinity maps later this year."Aquarius is a critical component of our Earth sciences work, and part of the next generation of space-based instruments that will take our knowledge of our home planet to new heights," said NASA Deputy Administrator Lori Garver. "The innovative scientists and engineers who contributed to this mission are part of the talented team that will help America win the future and make a positive impact across the globe."Aquarius will measure salinity by sensing thermal microwave emissions from the water's surface with three microwave instruments called radiometers. When other environmental factors are equal, these emissions indicate the saltiness of surface water. A microwave radar scatterometer instrument will measure ocean waves that affect the precision of the salinity measurement.Because salinity levels in the open ocean vary by only about five parts per thousand, Aquarius will be able to detect changes as small as approximately two parts per 10,000, equivalent to about one-eighth of a teaspoon of salt in a gallon of water."Data from this mission will advance our understanding of the ocean and prediction of the global water cycle," said Michael Freilich, director of NASA's Earth Science Division in the Science Mission Directorate at agency headquarters in Washington. "This mission demonstrates the power of international collaboration and accurate spaceborne measurements for science and societal benefit. This would not be possible without the sustained cooperation of NASA, CONAE and our other partners."The Aquarius/SAC-D (Satellite de Aplicaciones Cientificas) observatory is a collaboration between NASA and Argentina's space agency, Comision Nacional de Actividades Espaciales (CONAE).Aquarius was built by NASA's JPL and the Goddard Space Flight Center in Greenbelt, Maryland. NASA's Launch Services Program at the Kennedy Space Center in Florida manages the launch.JPL will manage Aquarius through its commissioning phase and archive mission data. Goddard will manage Aquarius mission operations and process science data. CONAE is providing the SAC-D spacecraft, optical camera, thermal camera with Canada, microwave radiometer, sensors from various Argentine institutions and the mission operations center. France and Italy also are contributing instruments.

JIUQUAN, Gansu, Sept. 26 (Xinhua) -- Engineers are conducting the final preparations before launching China's first space laboratory module at the end of this week at a launch center in northwest China.The unmanned Tiangong-1 module was originally scheduled to be launched into low Earth orbit between Sept. 27 and 30. However, a weather forecast showing the arrival of a cold air mass at the Jiuquan Satellite Launch Center forced the launch to be rescheduled for Sept. 29 or 30, depending on weather and other factors."This is a significant test. We've never done such a thing before," said Lu Jinrong, the launch center's chief engineer.A full ground simulation was conducted on Sunday afternoon to ensure that the module and its Long March 2F carrier rocket are prepared for the actual launch.Cui Jijun, commander-in-chief of the launch site system and director of Jiuquan Satellite Launch Center, told Xinhua that they developed a new target spacecraft for the mission and made more than 170 technical improvements to the Long March 2F, China's manned orbital carrier rocket.Engineers have also made more than 100 updates at the launch site in order to make it compatible with the Tiangong-1, Cui added.The module will conduct docking experiments after entering orbit, which is the first step in China's space station program.Cui said the launch site has an updated computer center and command monitoring system and increased ability to adapt to changes in mission conditions, as well as the resources to handle both the launch and command duties. An integrated simulation training system for space launching has also been developed for the docking mission.The mission comes just one month after the Long March 2C rocket malfunctioned and failed to send an experimental satellite into orbit. The Tiangong-1 mission was subsequently rescheduled in order to allow engineers to sort out any problems that might occur during the launch.Cui said that engineers conducted a two-month comprehensive technical check on equipment at the launch site from March to May. The safety and reliability of all the instruments have been significantly improved."[The launch site] has the full conditions to conduct the Tiangong-1 mission," said Cui.The Tiangong-1 will remain in orbit for two years. During its mission, it will dock with China's Shenzhou-8, -9 and -10 spacecrafts.Unmanned docking procedures will be an essential step toward China achieving its goal of establishing a manned space station around 2020.

SAN FRANCISCO, June 13 (Xinhua) -- Google on Monday confirmed that it had signed an agreement to buy Admeld, an on-line advertising optimization firm, in a deal seen as the Internet search giant's latest move to bolster its on-line display ad business.Admeld, launched in 2007 and headquartered in New York City, has developed a service that can help on-line publishers manage their ad space more efficiently and profitably.Admeld now has more than 500 customers worldwide, among them are FOX News, IDG TechNetwork, Discovery and The Weather Channel, according to information posted on its website."By combining Admeld's services, expertise and technology with Google's offerings, we're investing in what we hope will be an improved era of flexible ad management tools for major publishers, " Neal Mohan, Google's vice president of display advertising, said in a blog post announcing the deal."We believe that this investment will be an important step to help on-line publishers, and will further improve and grow the display advertising industry as a whole," Mohan noted.On-line display ads usually appear in forms that consist of images and may be interactive. According to the Interactive Advertising Bureau, a U.S. trade association, display-related on- line ad revenue in the United States totaled nearly 10 billion U.S. dollars in 2010.Financial terms of the deal were not disclosed by the two companies. TechCrunch, a technology blog site, has reported that Google paid around 400 million dollars.

SYDNEY, July 15 (Xinhua) -- The world's first drug to increase life expectancy of people with advanced melanoma has been approved for use in Australia, local media reported on Friday.The breakthrough drug Yervoy got approval from the Therapeutics Good Association (TGA) on Friday amid hopes it could add two years to the life of people with the most lethal form of skin cancer but for whom other treatments have failed, the Australian Associated Press (AAP) said.Clearance for the drug's use in Australia follows similar approvals by the U.S. health regulator in March.Yervoy works by attacking and destroying cancer cells.Patients are hooked up to an intravenous drip once every three weeks for a total of four doses.Professor Peter Hersey, consultant immunologist to the Melanoma Institute Australia, said no other drug had improved survival rates like Yervoy."Not all patients respond to it but those who do have a good chance of living longer than they would have otherwise," Hersey told AAP.While it may improve survival rates, Yervoy can produce side effects from diarrhea and vomiting to serious blood infections and kidney failure.The average survival time for people with advanced melanoma is just six months.A global study of 676 people with melanoma found that 45 percent of patients given Yervoy were still alive after one year, according to AAP.More than 20 percent lived at least two years, with a small number managing to survive for six years.A separate study, published in June, which showed similarly improved survival rates for patients with newly diagnosed advanced melanoma, has raised hopes that Yervoy could be made more widely available.Melanoma is the fourth most common cancer in Australia, with 10, 300 people diagnosed each year.