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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

BEIJING, June 27 (Xinhuanet) -- A "lean gene" that helps people keep slim was found closely related to diabetes and heart disease, according to a study pulished in Nature Genetics journal on Sunday.The scientists from Britain’s Medical Research Council Epidemiology Unit conducted the study.After comparing the genetic codes of more than 75,000 people, a gene called IRS1 was spotted as the decisive factor to lower the fat level in human body.But in further study, IRS1 was found putting people to a 20 percent higher risk of developing heart disease and type-2 diabetes.The study warned that people who appear slim and fit might be also at risk.But scientists suggest that the study results did not change the general message for most people."While this study pointed to genes as one factor in determining the risk of developing these conditions, it was important to remember that lifestyle factors like diet, exercise, cutting out smoking and maintaining a healthy weight also play a vital role in reducing the risk," said Ruth Loos, who led the study.

BEIJING, Sept. 14 (Xinhuanet) -- Facebook unveiled a new feature called "smart lists" on Tuesday, giving its users an easier way to share photos, posts and updates with smaller groups of friends.The new function, which commences on Wednesday, borrows from the success of the Circles feature of Google+, which allows users to categorize friends into groups.With the new feature, Facebook can automatically put your friends into groups, with the first four being work, school, family and city, based on the information of colleges, workplaces and geographic locations in users' profiles.The feature is optional to use, and the lists are customizable."This is really something we have been working on for four years," Facebook director of product management Blake Ross told AFP, adding "We think this is the way people will make lists going forward."In the meantime, the social networking site has also come up with "close friends" and "acquaintances" options.People can read the updates of their "close friends" more prominently in their news feed and just big news of their "acquaintances", according to Naomi Gleit, the director of product at Facebook who worked on the new feature.

COPENHAGEN, May 30 (Xinhua) -- The number of confirmed E. coli cases has risen to 14 in Denmark, with at least 26 others suspected of having the intestinal infection, the National Serum Institute said Monday.Seven of the confirmed cases show symptoms of kidney failure which marks an advanced stage of the sickness, the institute said."Almost all of the 14 infected people have been in northern Germany recently except just one. There is a 24-year-old man from Jutland. He has not even been to Germany, so he does not quite fit with the rest of the pattern," said Kaare Moelbak, chief physician at the institute. "We do not know yet how he has been so unlucky to get this infection but we assume that it has been a person-to-person transmission, or that he has eaten infected vegetables," he added.Denmark's Veterinary and Food Administration (DVFA) had advised Danish consumers not to eat raw tomato, lettuce and cucumber from Germany, and cucumber from Spain.It is now checking Danish cucumbers for traces of E. coli, with results expected on Tuesday.