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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

WASHINGTON, July 26 (Xinhua) -- The District of Columbia Department of Health (DOH) in the U.S. announced Tuesday that it has positively identified the West Nile Virus in mosquito samples in the District.This is the first time this summer the West Nile Virus has been identified in the U.S. capital."Residents should take caution as mosquitoes have the potential to transmit West Nile Virus to humans, and it is important for residents to take the necessary steps to avoid contracting the virus," DOH said in a statement.West Nile Virus is mainly an infection of birds, but on occasions an infected mosquito may spread it to humans. The virus is not transmitted directly from birds to humans and the risk of infection is low. In human infections, the virus generally causes no symptoms, or may cause mild flu-like symptoms.Senior citizens and people with weak immune systems are considered high risk for suffering the worst from the disease, officials said."People with a higher risk of infection should wear long- sleeved shirts, long pants, and apply insect repellent with DEET or other mosquito repellents to exposed skin according to manufacturer's directions. For children, they should use a product with DEET concentration of less than 30 percent," DOH said.

SAN FRANCISCO, July 12 (Xinhua) -- U.S. videogame giant Electronic Arts Inc. (EA) on Tuesday said it has agreed to buy PopCap Games, a leading provider of casual games for digital platforms, in a deal to accelerate its digital transformation.EA said it will pay about 650 million U.S. dollars in cash and 100 million dollars in shares of EA common stock to acquire privately-held PopCap, the maker of blockbuster games including " Plants vs. Zombies," "Bejeweled" and "Zuma".In addition, PopCap's owners are entitled to receive as much as 550 million dollars in earn-outs if certain earnings targets are met through December 2013, according to EA, which is headquartered in Redwood City in the U.S. state of California.Logos of PopCap Games and Electronic Arts Inc."EA and PopCap are a compelling combination," John Riccitiello, EA's chief executive officer, said in a statement."PopCap's great studio talent and powerful IP add to EA's momentum and accelerate our drive towards a 1-billion-dollar digital business," he noted.PopCap is one of the largest providers of casual videogames for mobile phones, tablets, PCs and social network sites, with more than 150 million games installed and played worldwide on platforms such as Facebook, RenRen, Google, iPhone, iPad and Android.EA said the purchase of PopCap is expected to close in August this year, subject to customary closing conditions including regulatory approvals.

BEIJING, Sept. 8 (Xinhuanet) -- Middle-aged white women drinking alcohol moderately are more likely to stay healthy than nondrinkers, according to a new study from Harvard.The study has followed about 14,000 mostly white women since 1976.As a result, compared with teetotalers, those who had 3 to 15 alcoholic drinks weekly in their late 50s were 28 percent higher of being free from physical disability, chronic illness, mental health problems, and cognitive decline at the age of 70.Even having just one or two drinks per week increased a woman's odds of good health by 11 percent.However, women should be aware that even moderate drinking has been linked to an increased risk of breast cancer, said Qi Sun, M.D., a lead author of the study and a nutrition researcher at the Harvard School of Public Health.These findings don't necessarily apply to men or to nonwhite women. But they reinforced the evidence for the health benefits of moderate drinking.

HOUSTON, July 25 (Xinhua) -- A shelter-in-place was ordered after a battery caught fire during a testing at NASA's Johnson Space Center Monday morning.A battery was being tested inside a containment system when it got overheated and caught fire at about 9 a.m. local time, ABC quoted the Houston Fire Department (HFD) sources as reporting.A shelter-in-place was issued for a few buildings because it's believed that one of the bi-products of the combustion could be dangerous, HFD said.The fire was put out before 11:30 a.m.A firefighter was injured when a hydrant cap blew off and struck him, according to ABC.

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