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Researchers published what they say is the first case of a living person diagnosed with the degenerative brain disease chronic traumatic encephalopathy or CTE.While unnamed in the study, lead author Dr. Bennet Omalu confirmed to CNN that the subject of the case was former NFL player Fred McNeill -- who died in 2015.Omalu is credited with first discovering CTE in professional football players. Until now, the only way to diagnose the disease is with a brain exam after death.The diagnosis was first made using an experimental brain scan that can trace a signature protein of CTE called tau. The authors then confirmed the diagnosis with an autopsy. The case study was published in the journal Neurosurgery this week.'It looked like just depression'Omalu first presented these findings exclusively to CNN's chief medical correspondent, Dr. Sanjay Gupta, in 2016. McNeill's wife, Tia, and his two sons, Gavin and Fred Jr., told Gupta then that they saw Fred transform from a fun loving family man at the center of their lives into a man who was dealing with symptoms of memory loss, anger and depression that tore their family apart."There are some times where the father is the stronghold in the family, or the anchor. If you lose that, everything kind of falls apart. That's kind of what happened for us. It looked like financial issues at first; it looked like marital issues, and they separated; then it looked like just depression," Gavin told Gupta.CTE is known for plaguing people with Alzheimer's like symptoms such as memory loss, rage, mood swings, and in some cases, suicidal ideation.Severity of the disease is categorized into four stages, with stage 4 being the most severe. While researchers don't know exactly why certain people develop the disease and others don't, they believe that it results from repeated blows to the head that trigger a build up of tau proteins in the brain.CTE has been called football's "concussion crisis," however experts point out that CTE can develop from any repeated head injury. According to the Boston University CTE Center, "this trauma includes both concussions that cause symptoms and subconcussive hits to the head that cause no symptoms." These subconcussive hits can include the repeated trauma the brain experiences from constant plays, hitting the turf, and tackling. Wrestlers, boxers, and military troops have also been diagnosed with the disease.Seeing CTEWhile McNeill is the first case to be confirmed with an autopsy, the experimental technology has been used on at least a dozen other former NFL players, including Pro Football Hall of Famer, Dallas Cowboy Tony Dorsett. Omalu helped develop and is invested in the diagnostic exam, which uses a radioactive "tracer" called FDDNP to bind to tau proteins in the brain. The tau proteins can then be seen on a PET scan of the brain.Critics have said the protein also can highlight another protein called amyloid, which may be indicative of Alzheimer's or other forms of dementia. But Omalu noted that in CTE, tau makes distinctive patterns in the brain. It has a "specific topographic signature," he said, and that pattern can be detected in imaging.Omalu said he and his team are currently raising money to start a phase 3 clinical trial to further test the technology and replicate what they have seen in McNeill. He anticipates that once funds are raised, it will take another two to three years for the trial and then another year, at least, for approval from the US Food and Drug Administration. When asked, how soon a commercial test could be available, Omalu predicted it could be as soon as a few years. "We are looking at less than five years," he said.  3711

Protests, elections, COVID-19--these are some of the factors experts say are leading to the rise of gun sales this year.“There’s just so much happening right now to make people feel uncertain, and I think that’s the one thing that might explain gun sales,” said Trent Steidley, a sociologist and Assistant Professor at the University of Denver.Steidley focuses on topics like firearms and society.“First, it was COVID to think about. OK, people are probably feeling unsure about a lot of things, and we know uncertainty kind of correlates with gun sales. It can go with things like a recession, it can go with things like unemployment,” he explained. “What we've seen now is about four months of pretty heavy gun sales.”A firearm industry survey conducted by the NSSF showed handguns outpaced shotguns 2 to 1 in sales among first-time gun buyers, following a larger, rising trend Steidley has been watching.“Before 2012, 2013, long guns, shotguns, rifles, consistently outpaced handguns. Slowly over time, that ratio changed though,” he said.FBI firearm background check data appears to coincide with two major events. The top two highest weeks for checks since 1998 were March 16 through March 22 of this year with 1,197,788 checks, and June 1 through June 7 with 1,004,798 checks. For reference, March 13 was the day President Donald Trump announced the national emergency for coronavirus and May 25 was the day of George Floyd’s death in Minneapolis.“It’s human nature. People feel threatened in some way, either they feel their rights might be threatened,” Sheriff Justin Smith in Larimer County, Colorado said. “You can’t go on the internet or watch TV and pick up the news and not see some very concerning stories on spikes in violence around the country.”Smith said his department has seen an increase in those applying for concealed handgun permits.“The numbers are certainly on the increase. We just can’t say because a lot of folks are stuck waiting. We’re clear into September on appointments right now, but I definitely get that sense those numbers are up,” he said.The response from Steven Reams, Weld County Sheriff, echoed the same:“I’ve definitely seen a marked increase in concealed weapon permit applications. It started to increase in mid-March and then there was a dramatic increase in June, and then another in July. It seems that most applicants are not necessarily all new gun owners, more than half are people who just decided it was a good time to start carrying. The balance of the applicants are largely first time gun buyers.”Surveys from the NSSF show firearm retailers believe 40 percent of all guns purchased this year have been by first-time buyers, which has brought training and safety to the forefront.“Representatives of the industry and trainers are all aware there's a need to get these people trained up on how to use a gun safely, how to store a gun, proper safety protocols,” Steidley said.“Training is a must,” Steve Allred said. “I would say probably 50 percent of my students never even held a gun.” Allred leads gun safety and self-defense courses in Wyoming. COVID-19 impacted what he’s able to do, but thanks to technology, he’s figured out a solution.“We ran five, six, seven classes every year in the summer mainly,” he said. “April is usually when we start classes. We just decided everyone's kind of going to the Zoom thing. Anyways, we can provide the class live.”There are limitations of what Allred can teach virtually, but he offers anyone who takes the class to join him on the range, as well.“What it’s allowed us to do is it's allowed us to instead of concentrate locally, we’re having students all over the country,” he said.While feelings of uncertainty fuel firearm sales, Allred said no matter someone’s reason for buying a gun, it’s important they know how to use it.“Why do I want a gun? Why do I push my wife to train with her weapon? And it boils down to just the ability to protect when you least expect it,” he said. 3992

President Donald Trump signed a 0 billion stimulus bill on Sunday, with some of those funds going toward direct payments for millions of Americans. While the bill has been signed into law, there are still a number of unknowns about the bill.Here is what is known:- Congress has authorized that most Americans making less than ,000 a year will get a direct payment of 0 (couples making less than 0,000 a year will get ,200). Heads of households making 4,500 annually also will receive the full 0.- Those making ,000 to ,000 (0,000 to 4,000 for couples) will get a prorated check. Those making over ,000 (4,000 for couples) will not receive a check.- Once again, young adults considered dependents of their parents are not eligible for the payments.- The amount given per child under the age of 17 will increase from 0 to 0.- Americans will receive the second round of stimulus checks the same way they received the first one.- While most Americans who received a stimulus check in the spring will receive one, changes to income between 2018 and 2019 could alter payments.What is unknown:- Will Congress authorize an increase of the direct payments from 0 to ,000. Trump called on an increase to direct payments, which got support from the House on Monday, mostly due to strong Democratic support. Now the bill goes to the Senate, but it is unknown if the bill will even get a vote there.- When a check will be distributed. Treasury Secretary Steven Mnuchin says that checks could be distributed within a week, but with Congress considering an increase to the amount per check, that could delay things.Why would I qualify for a check in the spring, but not now?This would mostly be due to a change in income. The IRS went by income from the most recent tax return that had been submitted by the spring. The filing deadline for 2019 taxes was July 15. For many Americans, the IRS used 2018 return information. If someone saw their income increase from 2018 to 2019, that information would now be in the IRS’ hands.Conversely, if your income dropped in 2019 compared to 2018, that might make you eligible for a check this time around.Undocumented immigrants still will not receive a check, but their spouses mayDuring the last round of stimulus checks, many families did not receive a check if an undocumented immigrant is in the family. Now, the spouses and children of undocumented immigrants can now receive a check (assuming they meet qualifications), and also retroactively earn a check from the last round of stimulus.When will we know if I will get 0 or ,000That will be decided in the coming days. The Senate is scheduled to meet on Tuesday. Theoretically, the Senate could approve the House’s bill on Tuesday, and Trump could sign later in the day.Regardless, a new Congress is sworn in on Sunday, and the Senate has until then to consider the legislation passed by the House on Monday. 2953

RANCHO BERNARDO (KGTV) - A 54-year-old man was pinned between two cars when he was rear-ended by a teen later arrested on suspicion of driving under the influence. The victim was towing his Nissan Sentra in a BMW when he stopped check the tow straps in the 14900 block of Camino Del Norte in Rancho Bernardo around 9 p.m. Saturday. Related: Valley Center wrong-way head-on crash As he stood between the two vehicles a 16-year-old boy in a 2000 Nissan Xterra rear-ended the vehicles and pinned him between both the BMW and Nissan Sentra.According to Officer Robert Heims, the force of the collision broke both of the man's legs. The injuries were deemed non-life threatening and the victim was taken to a hospital.Related: Suspected 16-year-old drunk driver arrested after crash A 54-year-old woman was also riding in the Sentra when the accident occurred. She complained of pain but was not hospitalized.The teen was arrested under suspicion of drunk driving charges.   1002

President Donald Trump was infuriated after it quickly leaked that he had been directly instructed by his national security advisers in briefing materials not to congratulate Russian President Vladimir Putin on his recent election victory during their call Tuesday morning, a source familiar with the President's thinking said.Trump was fuming Tuesday night, asking his allies and outside advisers who they thought had leaked the information, noting that only a small group of staffers have access to those materials and would have known what guidance was included for the Putin call, the source said.According to the source, the incident resurfaces his long-held belief there are individuals inside his administration -- especially in the national security realm -- who are actively working to undermine him. 817