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SAN FRANCISCO, July 7 (Xinhua) -- Apple announced Thursday that over 15 billion applications have been downloaded from its App Store by more than 200 million Apple mobile devices users worldwide."Thank you to all of our amazing developers who have filled it with over 425,000 of the coolest apps and to our over 200 million iOS users for surpassing 15 billion downloads," said Phillip Schiller, Apple's senior vice president of worldwide product marketing, in a statement.Launched on July 10, 2008, Apple's digital application distribution platform has been growing at a fast speed. It took nine months to hit one billion downloads and five billion in June 2010. In January, Apple gave a 10,000-U.S. dollar App Store gift card to a user who downloaded the 10 billionth application.In Thursday's statement, the Cupertino, California-based company said it had paid developers 2.5 billion dollars to date.Apple's mobile market place is far ahead of Google's Android Market. At its annual I/O conference in May, Google said there had been 4.5 billion app installs so far. But Google said the growth of its mobile operating system and applications is accelerating with its store hitting another billion downloads every 60 days.Currently, Apple is in a legal battle against Amazon over the use of "Appstore," which the online retailer launched in March to sell mobile applications to Google's Android platform users.On Wednesday, a federal judge denied Apple's request to immediately stop Amazon from using the term "Appstore."Meanwhile, Amazon, Microsoft, HTC, Nokia and Sony Ericsson have filed complaints against Apple in Europe, seeking to get Apple's trademarks for "App Store" and "Appstore" invalidated.

WASHINGTON, June 14 (Xinhua) -- Eating a low-carbohydrate, high- protein diet may reduce the risk of cancer and slow the growth of tumors already present, according to a study published Tuesday in Cancer Research, a journal of the American Association for Cancer Research.The study was conducted in mice, but the scientists involved agree that the strong biological findings are definitive enough that an effect in humans can be considered."This shows that something as simple as a change in diet can have an impact on cancer risk," said lead researcher Gerald Krystal, a scientist at the British Columbia Cancer Research Center.Krystal and his colleagues implanted various strains of mice with human tumor cells or with mouse tumor cells and assigned them to one of two diets. The first diet, a typical Western diet, contained about 55 percent carbohydrate, 23 percent protein and 22 percent fat. The second, which is somewhat like a South Beach diet but higher in protein, contained 15 percent carbohydrate, 58 percent protein and 26 percent fat. They found that the tumor cells grew consistently slower on the second diet.As well, mice genetically predisposed to breast cancer were put on these two diets and almost half of them on the Western diet developed breast cancer within their first year of life while none on the low-carbohydrate, high-protein diet did. Interestingly, only one on the Western diet reached a normal life span ( approximately 2 years), with 70 percent of them dying from cancer while only 30 percent of those on the low-carbohydrate diet developed cancer and more than half these mice reached or exceeded their normal life span.Krystal and colleagues also tested the effect of an mTOR inhibitor, which inhibits cell growth, and a COX-2 inhibitor, which reduces inflammation, on tumor development, and found these agents had an additive effect in the mice fed the low-carbohydrate, high-protein diet.When asked to speculate on the biological mechanism, Krystal said that tumor cells, unlike normal cells, need significantly more glucose to grow and thrive. Restricting carbohydrate intake can significantly limit blood glucose and insulin, a hormone that has been shown in many independent studies to promote tumor growth in both humans and mice.Furthermore, a low-carbohydrate, high-protein diet has the potential to both boost the ability of the immune system to kill cancer cells and prevent obesity, which leads to chronic inflammation and cancer.

LOS ANGELES, June 17 (Xinhua) -- The size of low-oxygen zones created by respiring bacteria is extremely sensitive to changes in depth caused by oscillations in climate, thus posing a distant threat to marine life, a new study suggests."The growth of low-oxygen regions is cause for concern because of the detrimental effects on marine populations -- entire ecosystems can die off when marine life cannot escape the low- oxygen water," said lead researcher Curtis Deutsch, assistant professor of atmospheric and oceanic sciences at University of California, Los Angeles."There are widespread areas of the ocean where marine life has had to flee or develop very peculiar adaptations to survive in low- oxygen conditions," Deutsch said in the study to be published in an upcoming print edition of the journal Science.A team led byDeutsch used a specialized computer simulation to demonstrate for the first time that fluctuations in climate can drastically affect the habitability of marine ecosystems.The study also showed that in addition to consuming oxygen, marine bacteria are causing the depletion of nitrogen, an essential nutrient necessary for the survival of most types of algae."We found there is a mechanism that connects climate and its effect on oxygen to the removal of nitrogen from the ocean," Deutsch said. "Our climate acts to change the total amount of nutrients in the ocean over the timescale of decades."Low-oxygen zones are created by bacteria living in the deeper layers of the ocean that consume oxygen by feeding on dead algae that settle from the surface. Just as mountain climbers might feel adverse effects at high altitudes from a lack of air, marine animals that require oxygen to breathe find it difficult or impossible to live in these oxygen-depleted environments, Deutsch said.Sea surface temperatures vary over the course of decades through a climate pattern called the Pacific Decadal Oscillation, during which small changes in depth occur for existing low-oxygen regions, Deutsch said. Low-oxygen regions that rise to warmer, shallower waters expand as bacteria become more active; regions that sink to colder, deeper waters shrink as the bacteria become more sluggish, as if placed in a refrigerator."We have shown for the first time that these low-oxygen regions are intrinsically very sensitive to small changes in climate," Deutsch said in remarks published Friday by the American Association for the Advancement of Science on its website. "That is what makes the growth and shrinkage of these low-oxygen regions so dramatic."Molecular oxygen from the atmosphere dissolves in sea water at the surface and is transported to deeper levels by ocean circulation currents, where it is consumed by bacteria, Deutsch said."The oxygen consumed by bacteria within the deeper layers of the ocean is replaced by water circulating through the ocean," he said. "The water is constantly stirring itself up, allowing the deeper parts to occasionally take a breath from the atmosphere."A lack of oxygen is not the only thing fish and other marine life must contend with, according to Deutsch. When oxygen is very low, the bacteria will begin to consume nitrogen, one of the most important nutrients that sustain marine life."Almost all algae, the very base of the food chain, use nitrogen to stay alive," Deutsch said. "As these low-oxygen regions expand and contract, the amount of nutrients available to keep the algae alive at the surface of the ocean goes up and down. "Understanding the causes of oxygen and nitrogen depletion in the ocean is important for determining the effect on fisheries and fish populations, he said.

CANBERRA, Aug. 29 (Xinhua) -- Alzheimer Australia on Monday released a GPS device for people with dementia, in a move to give them greater independence, while reducing the burden of missing person searches for police.The technology has been using in New South Wales of Australia, and is now available for people in state Victoria.The Safe2Walk locater can be worn by people with dementia on a lanyard around the neck or clipped onto a belt. Families can log- on to the connected website and see where the person is.The device updates the person's location every 60 seconds, reducing stress for carers so they know when a person with dementia might be wandering.It also works as a mobile phone, letting the person wearing the device to make instant calls to family.According to Alzheimer's Australia's research manager Jason Burton, the device aimed to stop vulnerable people getting lost, with research showing about 40 percent of people with dementia went missing at least once."In 99 percent of cases the carer has gone to pick them up, but there was one case where they couldn't and the police were able to contact us to get the exact GPS location of this person to rescue them," Burton told Herald Sun.A Victoria Police spokeswoman said while it could not endorse a specific product, if the device could alert carers when a person with dementia first became disorientated, the response could help avoid a large-scale police search.Mina Sapounakis, who's father has worn the Safe2Walk device, said it has given her family a sense of calm."We could go grocery shopping without stressing and rushing back home quickly to check on Dad," she said."There were a few times he had gone wandering and we were able to easily find him without having to call the police."The Safe2Walk GPS costs under 15 U.S. dollars a week for rent.

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