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Drugmaker Bristol-Myers Squibb announced Thursday a billion deal to buy Celgene, in one of the biggest mergers in pharmaceutical industry history.The deal, which still needs the approval of shareholders and regulators, will be paid with a combination of stock and cash. Bristol-Myers is the result of a 1989 merger of two companies that traced their roots back to the 19th century, and is the eighth largest US drugmaker, with annual revenue of .8 billion in 2017. Celgene is the ninth largest with revenue of billion.The combined company could become the fourth largest pharmaceutical company in the United States.Shares of Bristol-Myers ( 663

Detroit police are investigating the shooting death of a University of Michigan – Dearborn student athlete.Kabria Arnold, 20, who played softball for the university, was killed Sunday. Her body was found lying in the street. According to the UM – Dearborn website, Arnold entered her first season with the softball team as a junior. It also states that she's a Southfield resident. 394

Coca-Cola wants Americans to give Coke Energy a shot.The beverage company will start selling four varieties of its energy drink — Coca-Cola Energy, Coca-Cola Energy Zero Sugar, Coca-Cola Energy Cherry and Coca-Cola Energy Cherry Zero Sugar — in the United States in mid-January. Coke Energy and Coke Energy Zero Sugar are already available internationally, but the cherry flavor is new.The new product is designed to help Coke to introduce Coca-Cola drinkers, who may not consume energy drinks, to a growing category. It's also a way for the company to make sure that its core Coca-Cola brand remains fresh.But first, Coca-Cola has to make sure drinkers understand just what Coke Energy is.A boost of energyCoca-Cola Energy has 114 mg of caffeine in each 12-ounce serving.That's nearly four times the caffeine in a can of regular Coca-Cola (34 mg), and three times the caffeine in a can of Diet Coke (46 mg).It will be more expensive, too: Coca-Cola Energy will have a recommended price of .49 per 12-ounce container. Similarly-sized regular Cokes are generally sold in packs of 12, and cost about per package (about 33 cents each).In the United States, total energy drink and energy shot sales reached about .5 billion in 2018, up 30% from 2013, according to a report from research group Mintel. The sector could have sales of about billion in 2023, Mintel projects.Coke drinkers aren't really in on the trend, according to Coca-Cola Brand Director Janki Gambhir."Many consumers that drink Coke don't engage in the energy category today," she told CNN Business, noting that they still may be interested. "A lot of the work that we will do will be focused around educating consumers," she said.To figure out how to make Coke Energy work in the United States, the company spoke with more than 1,100 people — including energy drink consumers and those that don't regularly drink the beverage — to make sure that it delivers what people want. The company plans to introduce the product by advertising it through television commercials and billboards, as well as handing out samples.With Coca-Cola Energy, the company hopes to boost sales within the Coke brand rather than steal share from other energy drinks or Coke flavors. Coca-Cola owns about 18% of Monster Energy, and has a strategic partnership with the company.In addition to giving Coca-Cola another way into the energy sector, Coke Energy can help make sure people don't stop drinking Coke.Keeping Coke currentCoca-Cola has ambitions of being a "global beverage company." It sells iced tea, juice, water, coffee and smoothies. But Coke is its core business, and only a few years ago the Coke brand was stagnating.To boost the brand, Coca-Cola has given Diet Coke a millennial-friendly makeover, launched a new flavor and, for a limited time, brought back New Coke in partnership with Netflix's "Stranger Things." Coca-Cola Energy and Coca-Cola Plus Coffee, which is for now only available internationally, are more ways to keep people excited about cola.So far, Coca-Cola's efforts to revitalize its core brand seem to be working. Second quarter sales were driven in part by 4% global growth in trademark Coca-Cola, the company said. And international sales of Coke Energy are "encouraging," said CEO James Quincey in a July call discussing the quarter's financial results .Coca-Cola hopes that Coke Energy will be a continued source of long term growth, said Gambhir, adding that there is a "pipeline full of new flavors" and other innovations for the platform. 3543

Dick Pound, the longest-serving member of the IOC, estimates there’s a three-month window to decide the fate of the Tokyo Olympics, which are being threatened by the fast-spreading virus from China.Pound, in an exclusive interview with The Associated Press, did not sound alarmist. But he did speak frankly about the risks facing the Olympics, which open July 24. Pound has been an International Olympic Committee member since 1978, 13 years longer than current President Thomas Bach.“You could certainly go to two months out if you had to,” Pound said, which would mean putting off a decision until late May and hoping the virus is under control. “A lot of things have to start happening. You’ve got to start ramping up your security, your food, the Olympic Village, the hotels, The media folks will be in there building their studios.”And if it got to the point of not going ahead, Pound speculated “you’re probably looking at a cancellation.”“This is the new war and you have to face it. In and around that time, I’d say folks are going to have to ask: ‘Is this under sufficient control that we can be confident about going to Tokyo, or not?’”China on Tuesday reported 508 new cases and another 71 deaths, 68 of them in the central city of Wuhan, where the epidemic was first detected in December. The updates bring mainland China’s totals to 77,658 cases and 2,663 deaths. South Korea now has the second-most cases in the world with 977, including 10 deaths. Clusters of the illness are now appearing in the Middle East and Europe. This could signal a new stage in the spread of the virus with four deaths reported in Japan.Pound encouraged athletes to keep training. About 11,000 are expected for the Olympics, and another 4,400 for the Paralympics, which open on Aug. 25.“As far as we all know you’re going to be in Tokyo,” Pound said. “All indications are at this stage that it will be business as usual. So keep focused on your sport and be sure that the IOC is not going to send you into a pandemic situation.”The modern Olympics dating from 1896 have only been cancelled during wartime, and faced boycotts in 1976 in Montreal, in 1980 in Moscow and 1984 in Los Angeles — all in Pound’s memory. The Olympics in 1940 were to be in Tokyo, but were called off because of Japan’s war with China and World War II.Pound called uncertainty a major problem and repeated the IOC’s stance — that it’s depending on consultations with the World Health Organization, a United Nations body, to make any move. So far, the games are on.“It’s a big, big, big decision and you just can’t take it until you have reliable facts on which to base it,” Pound said. He said whatever advice the IOC is now getting, “it doesn’t call for cancellation or postponement of the Olympics. You just don’t postpone something on the size and scale of the Olympics. There’s so many moving parts, so many countries and different seasons, and competitive seasons, and television seasons. You can’t just say, we’ll do it in October.”If changes have to be made, Pound said every option faced obstacles.Pound said moving to another city seemed unlikely. “To move the place is difficult because there are few places in the world that could think of gearing up facilities in that short time to put something on,” Pound said.London mayoral candidate Shaun Bailey has suggested the British capital as an alternative. Tokyo Gov. Yuriko Koike suggested that was an inappropriate offer, using the virus as political campaign fodder.Pound said he would not favor a dispersal of events over various venues because that wouldn’t “constitute an Olympic Games. You’d end up with a series of world championships.” He said it would be very difficult to spread around all these sports in a 17-day period with only a few month’s notice.Staying in Tokyo but moving it back a few months would be unlikely to satisfy North American broadcasters, whose schedules are full in the fall with American football, college football, European soccer, basketball, baseball, and ice hockey. Of course, other world broadcasters also have jammed schedules.“It would be tough to get the kind of blanket coverage that people expect around the Olympic Games,” Pound said. “It’s certainly tougher than it would have been in 1964 in Tokyo when you didn’t have the saturation sports schedule on television.”How about delaying for a year, but staying in Tokyo? Japan is officially spending .6 billion to organize the Olympics, although a national audit board says the country is spending twice that much.“Then you have to ask if you can hold the bubble together for an extra year,” Pound said. “Then of course you have to fit all of this into the entire international sports schedule.”Pound said the IOC has been building up an “emergency fund” for such circumstances, reported to be about billion. That could fund international sports federations who depend on income from the IOC to operate — and the IOC itself.“This would be what you normally call a force majeure,” said Pound, a Canadian lawyer by training, using the legal phrase for “unforeseeable circumstances.”“It’s not an insurable risk and it’s not one that can be attributed to one or the other of the parties. So everybody takes their lumps. There would be a lack of revenue on the Olympic Movement side.”He said broadcasters may have their own insurance that would “mitigate some of the losses.”About 73% of the IOC’s .7 billion income in a four-year Olympic cycle is from broadcast rights.Pound said the future of the Tokyo Games was largely out of the IOC’s hands, depending on the virus and if it abets.“If it gets to be something like the Spanish Flu,” Pound said, referring to a deadly pandemic early in the 20th century that killed millions. “At that level of lethality, then everybody’s got to take their medicine.”___More AP sports: 5855

DENVER, Colo. — On a clear October day in 1970, travelers were making their way along Loveland Pass. At about 11,900-foot elevation, most wouldn't expect to see an airliner flying in the valley below. But eyewitnesses at that elevated location 256

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