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SAN FRANCISCO, July 15 (Xinhua) -- U.S. microblogging platform Twitter on Friday marked its fifth anniversary since public debut."Twitter, then called Twttr, opened to the public five years ago today," the company said in a Tweet, a short message within 140 characters users are allowed to communicate on the website."Twttr is a new mobile service that helps groups of friends bounce random thoughts around with SMS," co-founder Biz Stone described the service in a blog post on July 13, 2006, two days before its public debut."There were 224 Tweets sent on July 15, 2006. Today, users send that many Tweets in less than a tenth of a second," said the San Francisco-based company.Twitter said more than 600,000 new users signed up on Thursday while it took it more than 16 months to reach the first 600,000 Twitter accounts.The tipping point for the service's popularity was the 2007 South by Southwest festival, a set of film, interactive and music festivals and conferences that take place every March in Austin, Texas. During the event, the Tweets sent per day grew from 20,000 to 60,000.With an estimated user base of 200 million worldwide, some 200 million Tweets are generated and 1.6 billion search queries are handled every day, the company said.According to research firm EMarketer, advertising sales on Twitter is expected to reach 150 million U.S. dollars this year. SharesPost, a secondary market for privately held companies, has assessed Twitter's current worth at 6.8 billion dollars.

WASHINGTON, June 16 (Xinhua) -- Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage. New research by a team of scientists at the University of Rochester has unveiled an important new mechanism that allows cells to recognize when they are under stress and prime the DNA repair machinery to respond to the threat of damage.Their findings will be published Friday in journal Science. Cells in the human body are constantly being exposed to stress from environmental chemicals or errors in routine cellular processes. While stress can cause damage, it can also provide the stimulus for undoing the damage.The scientists, led by biologists Vera Gorbunova and Andrei Seluanov, focused on the most dangerous type of DNA damage -- double strand breaks. Unrepaired, this type of damage can lead to premature aging and cancer. They studied how oxidative stress affects efficiency of DNA repair. Oxidative stress occurs when the body is unable to neutralize the highly-reactive molecules, which are typically produced during routine cellular activities.The research team found that human cells undergoing oxidative stress synthesized more of a protein called SIRT6. By increasing SIRT6 levels, cells were able to stimulate their ability to repair double strand breaks. When the cells were treated with a drug that inactivated SIRT6, DNA repair came to a halt, thus confirming the role of SIRT6 in DNA repair. Gorbunova notes that the SIRT6 protein is structurally related to another protein, SIR2, which has been shown to extend lifespan in multiple model organisms."SIRT6 also affects DNA repair when there is no oxidative stress," explains Gorbunova. "It's just that the effect is magnified when the cells are challenged with even small amounts of oxidative stress."SIRT6 allows the cells to be economical with their resources, priming the repair enzymes only when there is damage that needs to be repaired. Thus SIRT6 may be a master regulator that coordinates stress and DNA repair activities, according to Gorbunova.

SAN FRANCISCO, Aug. 17 (Xinhua) -- Microsoft's cloud-based software Microsoft Office 365 on Wednesday experienced its first major outage since its introduction in late June."At approximately 11:30 a.m. PDT, Microsoft became aware of a networking issue affecting customers of some Microsoft services hosted out of one of our North American data centers," said Steven Gerri, general manager for Microsoft Global Foundation Services, in a statement"We apologize for the inconvenience that Office 365 outage has caused today. We are working on resolving the issue," the software giant said via Twitter.Outages were reported in Chicago, Denver and New York City among other locations. According to tweets from affected users, they were unable to access their email and managers were unable to manage accounts.The outage lasted approximately five hours and services have been restored for the moment.According to Microsoft service-level agreement, Microsoft guarantees a 99.9 percent level of uptime. If it fails to reach 99.9 percent uptime, users are eligible for 25 percent service credit.As more industry giants try to entice users to move to the "cloud," a term refers to the management and provision of applications and data over the Internet, the downtime again reminds cloud computing users that they must prepare to deal with outages and rethink their dependency on the service, analysts said.Amazon has suffered two major cloud outages earlier this month and back in April, impacting some of its high-profile users like movie streaming service Netflix and location-based social networking Foursquare.Analysts recommend cloud users to store data with multiple service providers to minimize the risk and limit their dependency on cloud services for business-critical processes.Available in 40 countries and regions since June 28, Office 365, which Microsoft CEO Steve Ballmer said is "where Microsoft office meets the cloud," combines Microsoft Office, SharePoint Online, Exchange Online and Lync Online into a single cloud-based package for business users.

CANBERRA, Sept. 24 (Xinhua) -- Australian scientists on Saturday said a satellite due to re-enter Earth poses a negligible threat to life and property on Earth.U.S. National Aeronautics and Space Administration's Upper Atmosphere Research Satellite (UARS), which weighs more than five tons, is expected to re-enter the Earth's atmosphere at 1058 (AEST) on Saturday. The U.S.-based Center for Orbital and Re-entry Debris Studies estimates that re-entry could occur up to seven hours before or after this time.According to Nonathan Nally, a former editor of two space magazines and currently editor of the Australian Space News website, the satellite poses a negligible threat to life and property on Earth."Most of the satellite will burn up on re-entry, with perhaps as many as 26 stronger or harder small pieces surviving to reach the surface," Nally said in a statement."But with the majority of the Earth comprising oceans or uninhabited (or very sparsely populated) remote regions, the chances are overwhelming that any pieces of UARS that survive re- entry will fall harmlessly and never be seen again."Since the spacecraft is no longer powered, U.S. National Aeronautics and Space Administration has no control over where it comes down, but Nally said there is a small chance that debris from the satellite could land in Australia.Debris from SkyLab, another satellite which plunged to Earth, was scattered over parts of Western Australia in 1979. Skylab weighed about 77 tonnes, many times more than the UARS.?Dr Alice Gorman, a lecturer in the Department of Archaeology, specializing in space archaeology, at Flinders University in South Australia, said the UARS satellite re-entry is very reminiscent of Skylab in 1979."There is the same exaggeration of the hazard through the media, public anxiety as the advance warning allows for speculation, and a lack of understanding of what the risks actually are," he said in a statement."Should it land in Australia, we might expect the same rush for souvenirs as we saw with Skylab, as anything that has been in space has a special meaning on Earth."?UARS was launched on 12 September 1991 and decommissioned on 15 December 2005. Its total dry mass is about 5.5 tonnes. UARS is one of the largest NASA satellites to plunge back to Earth uncontrolled in the last 30 years.Since the beginning of the Space Age in the late-1950s, there have been no confirmed reports of an injury resulting from re- entering space objects.? Nor is there a record of significant property damage resulting from a satellite re-entry.

BEIJING, Aug. 25 (Xinhua) -- China pledged on Thursday to make more efforts to aid people living in the drought-stricken Horn of Africa in collaboration with the International Committee for the Red Cross (ICRC)."We noticed that the ICRC launched an appeal regarding the situation in the Horn of Africa. The Red Cross Society of China (RCSC) has decided to donate 4 million yuan (about 623,000 U.S. dollars) to the ICRC for its humanitarian aid in the region," said Hua Jianmin, president of the RCSC, while meeting with visiting ICRC President Jakob Kellenberger in Beijing on Thursday.Earlier this month, the RCSC donated 8 million yuan (1.25 million dollars) to famine-plagued countries in the Horn of Africa to be used for emergency humanitarian aid.A donation of 2 million yuan was sent to Kenya through the country's Red Cross organization, while another 2 million went to Ethiopia. The other 4 million yuan was donated to other countries in the region.The Chinese government has decided to provide a total of 90 million yuan (14 million dollars) in emergency food assistance to countries in the Horn of Africa."The Red Cross Society of China is willing to work together with the International Committee for the Red Cross to meet the needs of those who have been affected (by the droughts)," Hua said.Some 12.4 million people in Kenya, Ethiopia, Somalia and other countries in the region are in dire need of food due to a serious drought, the worst to hit the region since the 1980s.