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WASHINGTON, Aug. 4 (Xinhua) -- U.S. scientists have found two gene mutations occurring in oligodendrogliomas, the second-most common form of brain cancer, according to a study to be published Friday in journal Science.For years scientists have been looking for the primary cancer genes involved in oligodendrogliomas evolvement. Scientists know the two chromosomes held the probable mutations, but the particular gene information remains unclear.Now scientists at Duke University Medical Center and Johns Hopkins University have discovered the most likely genetic mutations that researchers have been hunting for on chromosomes 1 and 19.The genes they identified, CIC or FUBP1, are tumor suppressor genes. The cancer-related pathways that involve these genes could become targets for future treatments, said Hai Yan, a Duke associate professor of pathology and co-corresponding author of the study.The researchers found CIC on chromosome 19 and FUBP1 on chromosome 1 based on an initial study of seven oligodendrogliomas. They found six mutations and two mutations, respectively, in the seven tumors. Further study of 27 more of these tumors showed that there were 12 and three mutations of CIC and FUBP1, respectively. The two genes were rarely mutated in other types of cancers, indicating that they are oligodendroglioma-specific genes.These genes were difficult to find until the technology improved, said Yan."The team used whole genome sequencing technology so that no genes would be excluded, and we found to our surprise that one gene, on chromosome 19, was mutated in six out of the seven initial tumor specimens we sequenced," Yan said. "A mutation frequency of 85 percent is very high."The finding of two additional new genes involved in oligodendrogliomas increases the chances for an effective combination drug therapy for the tumor, Yan said. He envisions a combination cocktail of drugs similar to the combination-drug treatments taken by HIV patients that would target different pathways involved in cancer, and assist both in reducing the chance of relapsing and increasing odds of success.

WASHINGTON, Aug. 18 (Xinhua) -- Using integrated radar observations from a consortium of international satellites, NASA-funded researchers have created the first complete map of the speed and direction of ice flow in Antarctica, the U.S. National Aeronautics and Space Administration (NASA) announced Thursday.The map, which shows glaciers flowing thousands of miles from the continent's deep interior to its coast, will be critical for tracking future sea-level increases from climate change."This is like seeing a map of all the oceans' currents for the first time. It's a game changer for glaciology," said Eric Rignot of NASA's Jet Propulsion Laboratory and the University of California (UC), Irvine. Rignot is lead author of a paper about the ice flow published online Thursday in Science Express. "We are seeing amazing flows from the heart of the continent that had never been described before."Rignot and UC Irvine scientists used billions of data points captured by European, Japanese and Canadian satellites to weed out cloud cover, solar glare and land features masking the glaciers. With the aid of NASA technology, the team painstakingly pieced together the shape and velocity of glacial formations, including the previously uncharted East Antarctica, which comprises 77 percent of the continent.Like viewing a completed jigsaw puzzle, the scientists were surprised when they stood back and took in the full picture. They discovered a new ridge splitting the 5.4-million-square-mile landmass from east to west.The team also found unnamed formations moving up to 800 feet annually across immense plains sloping toward the Antarctic Ocean and in a different manner than past models of ice migration."The map points out something fundamentally new: that ice moves by slipping along the ground it rests on," said Thomas Wagner, NASA's cryospheric program scientist in Washington. "That's critical knowledge for predicting future sea level rise. It means that if we lose ice at the coasts from the warming ocean, we open the tap to massive amounts of ice in the interior."

SAN FRANCISCO, July 12 (Xinhua) -- U.S. videogame giant Electronic Arts Inc. (EA) on Tuesday said it has agreed to buy PopCap Games, a leading provider of casual games for digital platforms, in a deal to accelerate its digital transformation.EA said it will pay about 650 million U.S. dollars in cash and 100 million dollars in shares of EA common stock to acquire privately-held PopCap, the maker of blockbuster games including " Plants vs. Zombies," "Bejeweled" and "Zuma".In addition, PopCap's owners are entitled to receive as much as 550 million dollars in earn-outs if certain earnings targets are met through December 2013, according to EA, which is headquartered in Redwood City in the U.S. state of California.Logos of PopCap Games and Electronic Arts Inc."EA and PopCap are a compelling combination," John Riccitiello, EA's chief executive officer, said in a statement."PopCap's great studio talent and powerful IP add to EA's momentum and accelerate our drive towards a 1-billion-dollar digital business," he noted.PopCap is one of the largest providers of casual videogames for mobile phones, tablets, PCs and social network sites, with more than 150 million games installed and played worldwide on platforms such as Facebook, RenRen, Google, iPhone, iPad and Android.EA said the purchase of PopCap is expected to close in August this year, subject to customary closing conditions including regulatory approvals.

BEIJING, Sept. 26 (Xinhuanet) -- One of the world's brightest minds aims to bring to the world a new, advanced three-dimensional image technology that will leave other such technology in the shadows."Our new technology will be better than that used in Avatar," says Professor Yau Shing-tung of Harvard University."The image will be more vivid than with technologies used in previous movies. The new technology is not only quicker but cheaper."Yau is one of the world's greatest mathematicians, having won the prestigious Fields Medal. He was once the dean of the department of mathematics at Harvard, and is now a professor there. He is also a visiting professor at Tsinghua University.Professor Yau and his team met professionals from Tsinghua University and Renmin University of China last week, and they discussed possible cooperation to apply the technology in making a demonstration movie using the new technology.Yau and a team started working on the new 3D technology, founded on geometrical principles, at Harvard 10 years ago.What marks it out is the extremely vivid pictures it produces.3D technology is used not only in making movies and in Internet games but in other areas , such as medicine. Movie audiences the world over were awestruck by the technology used in the movie Avatar."After I watched the movie, all I could say was 'Wow'," said Shen Yiren, an IT staff worker in Zhongguancun Science and Technology Park Zone. "3D technology has extended the boundaries of the human imagination."Yau says that six years ago the makers of Avatar had wanted him to cooperate with them but he turned them down."I was not sure that (Avatar) would be such a big success."Avatar's facial caption technology puts points on models' faces while the new technology uses geometric methods, saving time and money, Yau says.